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H

Hiroyoshi Nishikawa

national cancer centre japan
H指数:65
被引数:2.5万

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On-demand GLUT3 expression augments CAR T cell metabolic fitness and antitumor efficacy in preclinical models of glioblastoma

按需GLUT3表达增强CAR T细胞在胶质母细胞瘤临床前模型中的代谢适应性和抗肿瘤效果

Science Translational Medicine
IF14.6
2026-04-010
PRE
Yamaguchi, Junya; Watanabe, Keisuke; Nakamura, Akihiro; Lin, Nina Yi-Tzu; Maeda, Sachi; Sugiyama, Daisuke; Kato, Shinichiro; Nagata, Akihito; Nishinakamura, Hitomi; Itahashi, Kota; Koyama, Shohei; Mizoguchi, Hiroyuki; Shiraki, Yukihiro; Enomoto, Atsushi; Ohka, Fumiharu; Motomura, Kazuya; Tsukada, Yuichiro; Ito, Masaaki; Maeda, Yuka; Ueda, Ryuzo; Natsume, Atsushi; Saito, Ryuta; Nishikawa, Hiroyoshi
Percentage of CD56+ monocytes at neutrophil engraftment is associated with the incidence of acute graft-versus-host disease

中性粒细胞植入时CD56+单核细胞的百分比与急性移植物抗宿主病的发生率相关

Annals of Hematology
IF2.4
2026-03-020
OAAI
Ken Hashimoto; Takahiko Sato; Yuichi Ishikawa; Yuki Okuhiro; Daisuke Sugiyama; He Zhang; Sachiko Ito; Yuichiro Inagaki; Kotaro Miyao; Masashi Sawa; Takanobu Morishita; Tatsunori Goto; Tetsuya Nishida; Nobuaki Fukushima; Kazutaka Ozeki; Ryo Hanajiri; Seitaro Terakura; Hiroyoshi Nishikawa; Hitoshi Kiyoi
Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade

对肿瘤抗原的体液IgG1反应是免疫检查点阻断的临床结果的基础

Nature Medicine
IF50
2026-01-270
OAAI
Edgar Gonzalez-Kozlova; Robert Sweeney; Igor Figueiredo; Kevin Tuballes; Sinem Ozbey; Pauline Hamon; Matthew D. Park; Giorgio Ioannou; Yohei Nose; Ruiwei Guo; Paula Restrepo; Mark Buckup; Vladimir Roudko; Clotilde Hennequin; Jessica Le Berichel; Nicholas Venturini; Laszlo Halasz; Leanna Troncoso; Alexandra Tabachnikova; Christie Chang; Amanda Reid; Haley Brown; Theodore Chin; Rafael Cabal; Raphaël Mattiuz; Shingo Eikawa; Diane Marie Del Valle; Tina Ruth Gonsalves; Nelson M. LaMarche; Hajra Jamal; Alona Lansky; Nancy Yi; Daniella Nelson; Jarod Morgenroth-Rebin; Raphael Merand; Bryan Villagomez; Darwin D’Souza; Emir Radkevich; Kai Nie; Zhihong Chen; Yasuko Tada; Hiroyoshi Nishikawa; Stephen C. Ward; Maria Isabel Fiel; Rachel Brody; Parissa Tabrizian; Ganesh Gunasekaran; Alice O. Kamphorst; Noah Cohen; Maria Curotto de Lafaille; Olivia Hapanowicz; Natalie Lucas; Kathy Wu; Nicola James; John C. Lin; Gavin Thurston; Myron Schwartz; Nathalie Fiaschi; Seunghee Kim-Schulze; Miriam Merad; Thomas U. Marron; Sacha Gnjatic
Mitochondrial DNA abundance is a determinant of immunogenic cell death in cancer

线粒体DNA丰度是癌症中免疫原性细胞死亡的决定因素

Immunity
IF26.3
2026-01-010
OA
Kosuke Tanaka; Yasuki Adachi; Takuma Irie; Tomoko Yamamori-Morita; Kazuhiro Kumagai; Takuya Owari; Genki Okumura; Yoshihisa Kobayashi; Hideaki Bando; Yuichiro Tsukada; Shogo Kumagai; Kota Itahashi; Eri Sugiyama; Hiroki Izumi; Yuji Shibata; Koichi Goto; Akihiro Ohashi; Susumu S. Kobayashi; Shohei Koyama; Hiroyoshi Nishikawa
Longitudinal remodeling of the tumor-immune microenvironment during regorafenib, nivolumab, and chemotherapy in advanced gastric cancer

在瑞戈菲尼、纳武利尤单抗和化疗过程中，晚期胃癌肿瘤-免疫微环境的纵向重塑

Science Translational Medicine
IF14.6
2026-01-010
PRE
Kota Itahashi; Akihito Kawazoe; Tadayoshi Hashimoto; Yue Yan; Takuma Irie; 小野宏美; Hitomi Tamura; Kyoko Hongo; Takashi Ikeno; Masashi Wakabayashi; Akihiro Sato; Yoshiaki Nakamura; Takao Fujisawa; Tomohiro Iwasawa; Tomoya Suzuki; Izuma Nakayama; Yasuhiro Kojima; Takayuki Yoshino; Hiroyoshi Nishikawa; Shohei Koyama; Kohei Shitara
Mutation of CMTR2 in Lung Adenocarcinoma Alters RNA Alternative Splicing and Reveals Therapeutic Vulnerabilities

CMTR2基因突变在肺腺癌中改变了RNA选择性剪接并揭示了治疗易感性

Nature Communications
IF15.7
2025-11-060
OAAI
Shigenari Nukaga; Kouya Shiraishi; Kenta Hamabe; Akifumi Mochizuki; Yu Hamaguchi; Emi Ogawa; Nguyen Thai Le; Yoko Shimada; Hanako Ono; Hitomi Nishinakamura; Yoshihisa Kobayashi; Junko Hamamoto; Ayako Ui; Mitsugu Araki; Yukari Sagae; Keiko Ohgino; Kai Sugihara; Satoshi Endo; Jun Miyakoshi; Yuichi Shiraishi; Hiroyuki Yasuda; Yasushi Okuno; Tatsuya Yoshida; Yasushi Goto; Yuichiro Ohe; Shun-Ichi Watanabe; Yasushi Yatabe; Hiroyoshi Nishikawa; Ryuji Hamamoto; Takashi Kohno; Takashi Nakaoku
KRAS mutations disrupt interactions between CD8+ T cells and antigen-presenting cells in the tumor microenvironment of biliary tract cancer

KRAS突变破坏胆道肿瘤微环境中CD8+ T细胞与抗原呈递细胞之间的相互作用

International Immunology
IF3.2
2025-11-011
PRE
Terasaki, Fumihiro; Kumagai, Shogo; Fukuda, Akito; Tanaka, Yosuke; Irie, Takuma; Ito, Sachiko; Yamada, Mihoko; Onoe, Shunsuke; Mizuno, Takashi; Kokuryo, Toshio; Koyama, Shohei; Karube, Kennosuke; Nishikawa, Hiroyoshi; Ebata, Tomoki
Microbiota-driven antitumour immunity mediated by dendritic cell migration

树突状细胞迁移介导的微生物驱动的抗肿瘤免疫

Nature
IF48.5
2025-07-140
OA
Nina Yi-Tzu Lin; Shota Fukuoka; Shohei Koyama; Daisuke Motooka; Dieter M. Tourlousse; Yuko Shigeno; Yuki Matsumoto; Hiroyuki Yamano; Kazutoshi Murotomi; Hideyuki Tamaki; Takuma Irie; Eri Sugiyama; Shogo Kumagai; Kota Itahashi; Tokiyoshi Tanegashima; Kaori Fujimaki; Sachiko Ito; Mariko Shindo; Takahiro Tsuji; Hiroaki Wake; Keisuke Watanabe; Yuka Maeda; Tomohiro Enokida; Makoto Tahara; Riu Yamashita; Takao Fujisawa; Motoo Nomura; Akihito Kawazoe; Koichi Goto; Toshihiko Doi; Kohei Shitara; Hiroyuki Mano; Yuji Sekiguchi; Shota Nakamura; Yoshimi Benno; Hiroyoshi Nishikawa
Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1+antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics

通过空间转录组学和血浆蛋白质组学鉴定与胃癌anti-PD-1/PD-L1抗血管生成相关的微环境特征

MOLECULAR CANCER
IF33.9
2024-09-131
OAAI
Cousin, Sophie; Guegan, Jean-Philippe; Shitara, Kohei; Palmieri, Lola Jade; Metges, Jean Philippe; Pernot, Simon; Fukuoka, Shota; Koyama, Shohei; Nishikawa, Hiroyoshi; Bellera, Carine A.; Adenis, Antoine; Gomez-Roca, Carlos A.; Cassier, Philippe Alexandre; Hollebecque, Antoine; Cantarel, Coralie; Kind, Michele; Soubeyran, Isabelle; Vanhersecke, Lucile; Bessede, Alban; Italiano, Antoine
An open label phase II study of lenvatinib with pembrolizumab and FLOT in the neoadjuvant and adjuvant treatment for patients with gastric and gastroesophageal junction adenocarcinoma (EPOC2001)

一项开放标签II期研究，评估lenvatinib联合pembrolizumab和FLOT在胃及胃食管结合部腺癌患者新辅助及辅助治疗中的应用（EPOC2001）。

ANNALS OF ONCOLOGY
IF65.4
2024-09-011
PRE
Kawazoe, A.; Koyama, S.; Nakayama, I.; Wakabayashi, M.; Furuya, H.; Tsukamoto, K.; Tamura, H.; Ikeno, T.; Sato, A.; Kojima, M.; Kuwata, T.; Fujita, T.; Kinoshita, T.; Nishikawa, H.; Shitara, K.
Three-year outcomes of preoperative chemoradiotherapy plus nivolumab in microsatellite stable and microsatellite instability-high locally advanced rectal cancer

术前放化疗联合nivolumab治疗微卫星稳定和微卫星不稳定高位局部晚期直肠癌的三年预后

BRITISH JOURNAL OF CANCER
IF6.8
2024-06-042
PRE
Tsukada, Yuichiro; Bando, Hideaki; Inamori, Koji; Wakabayashi, Masashi; Togashi, Yosuke; Koyama, Shohei; Kotani, Daisuke; Yuki, Satoshi; Komatsu, Yoshito; Homma, Shigenori; Taketomi, Akinobu; Uemura, Mamoru; Kato, Takeshi; Fukui, Makoto; Nakamura, Naoki; Kojima, Motohiro; Kawachi, Hiroshi; Kirsch, Richard; Yoshida, Tsutomu; Sato, Akihiro; Nishikawa, Hiroyoshi; Ito, Masaaki; Yoshino, Takayuki
Definitive chemoradiotherapy induces T-cell-inflamed tumor microenvironment in unresectable locally advanced esophageal squamous cell carcinoma

根治性放化疗诱导不可切除的局部晚期食管鳞状细胞癌的T细胞炎性肿瘤微环境

JOURNAL OF GASTROENTEROLOGY
IF5.5
2024-05-310
PRE
Habu, Takumi; Kumagai, Shogo; Bando, Hideaki; Fujisawa, Takeshi; Mishima, Saori; Kotani, Daisuke; Nakamura, Masaki; Hojo, Hidehiro; Sakashita, Shingo; Kinoshita, Takahiro; Yano, Tomonori; Mitsunaga, Shuichi; Nishikawa, Hiroyoshi; Koyama, Shohei; Kojima, Takashi
Prospective study on eribulin efficacy in advanced and metastatic breast cancer: changes in TGF-β compared to other standard chemotherapy agents (KBCSG-TR 2018, POTENTIAL)
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Nakayama, Takahiro; Yoshinami, Tersuhiro; Fujisawa, Fumie; Nishio, Minako; Yamanaka, Takashi; Yamashita, Toshinari; Oshiro, Chiya; Izui, Ayaka; Tomioka, Nobumoto; Maeda, Hideki; Shimoda, Masafumi; Shimazu, Kenzo; Tsuneizumi, Michiko; Matsunuma, Ryoichi; Bando, Hiroko; Ueda, Aya; Yasojima, Hiroyuki; Okada, Kumiko; Inoue, Kenichi; Kai, Yuichiro; Yoshidome, Katsuhide; Kawaguchi, Hidetoshi; Nagahashi, Masayuki; Oshima, Kazuteru; Kashiwagi, Shinichiro; Iwasa, Tsutomu; Taruno, Kanae; Tsuyuki, Shigeru; Tsukamoto, Fumine; Morimoto, Takashi; Kittaka, Nobuyoshi; Higuchi, Toru; Naito, Yoichi; Saita, Ryotaro; Nishikawa, Hiroyoshi; Sugiyama, Daisuke; Miyoshi, Yasuo; Uchida, Yohei; Yamada, Tomomi; Masuda, Norikazu
CD106 in Tumor-Specific Exhausted CD8+ T Cells Mediates Immunosuppression by Inhibiting TCR Signaling
CANCER RESEARCH
IF16.6
2024-04-181
PRE
Naoi, Yuto; Morinaga, Takao; Nagasaki, Joji; Ariyasu, Ryo; Ueda, Youki; Yamashita, Kazuo; Zhou, Wenhao; Kawashima, Shusuke; Kawase, Katsushige; Honobe-Tabuchi, Akiko; Ohnuma, Takehiro; Kawamura, Tatsuyoshi; Umeda, Yoshiyasu; Kawahara, Yu; Nakamura, Yasuhiro; Kiniwa, Yukiko; Yamasaki, Osamu; Fukushima, Satoshi; Kawazu, Masahito; Suzuki, Yutaka; Nishikawa, Hiroyoshi; Hanazawa, Toyoyuki; Ando, Mizuo; Inozume, Takashi; Togashi, Yosuke

研究方向

暂未获取到该数据
Y
Yosuke Togashi
H 指数:49论文数:530被引数:1.1万
D
Daisuke Sugiyama
H 指数:22论文数:75被引数:4,265
K
Kohei Shitara
H 指数:79论文数:1,129被引数:3.5万
S
Shohei Koyama
H 指数:48论文数:437被引数:1.4万
H
Hiroshi Shiku
H 指数:74论文数:777被引数:2.1万
L
Lloyd J. Old
H 指数:155论文数:961被引数:11.2万
S
Shogo Kumagai
H 指数:21论文数:84被引数:3,326
E
Eiichi Sato
H 指数:61论文数:479被引数:1.6万
S
Shimon Sakaguchi
H 指数:129论文数:832被引数:9.9万
T
Toshihiko Doi
H 指数:73论文数:830被引数:2.9万