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R

Roberto Zoncu

university of california berkeley
H指数:49
被引数:2.7万
浏览量:0

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A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation

TBK1/ULK1信号轴将溶酶体应激与TFEB激活相偶联

Nature
IF48.5
2026-09-300
PRE
Alessandra Esposito; Ibrahim Bayramoglu; Chiara Varriale; Maria Pia Cavaliere; Maria Elsa Brunetti; Rossella Agostinis; Rachel M. Jansen; Dan A. Tudorica; Yongjia Duan; Martina Spacci; Alessia Calcagnì; Carolin D. Strobl; Verena Passerini; Fabrizio Andreone; Jlenia Monfregola; Julia Richter; Francesca Sacco; Wolfram Klapper; Oliver Weigert; Andrea Ballabio; Roberto Zoncu; James H. Hurley; Joern Dengjel; Gennaro Napolitano
LASER couples damage sensing to ESCRT assembly for lysosome repair

激光将损伤感知与ESCRT组装耦合以用于溶酶体修复

Nature
IF48.5
2026-06-030
OAAI
Claire S. Goul; Aakriti Jain; Samira Yitiz; Zahra E. Soltani; Serim Yang; Simon Rapp; Martina Spacci; Scot Federman; James Sacco; Huinan Li; Lauren D. Enriquez; Nalan Liv; Laralynne Przybyla; Roberto Zoncu
Molecular and structural mechanisms of nutrient sensing in the mTORC1 pathway

mTORC1通路中营养素感知的分子与结构机制

Trends in Biochemical Sciences
IF11
2026-03-300
PRE
Serim Yang; Tong Bian; Roberto Zoncu
Lysosomes as hubs of metabolic sensing and cellular homeostasis

溶酶体是代谢感知和细胞稳态的枢纽

Molecular Cell
IF16.6
2026-01-280
PRE
Aakriti Jain; Roberto Zoncu
Reprogramming of cholesterol sensing in epithelial cells supports pancreatic inflammation

上皮细胞中胆固醇传感的重编程支持胰腺炎症

Molecular Metabolism
IF6.6
2025-12-020
OAAI
Giulia Milan; Olga A. Mareninova; Marco Fantuz; Martina Spacci; Carlotta Paoli; Jerik A. Pineda; Roberta Noè; Beatrice Calciolari; Roberto Zoncu; Anna S. Gukovskaya; Alessandro Carrer
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis
SCIENCE ADVANCES
IF12.5
2024-05-311
OAAI
Samson, Nolwenn; Bosoi, Cristina R.; Roy, Christian; Turcotte, Laurie; Tribouillard, Laura; Mouchiroud, Mathilde; Berthiaume, Line; Trottier, Jocelyn; Silva, Heitor C. G.; Guerbette, Thomas; Plata-Gomez, Ana Belen; Besse-Patin, Aurele; Montoni, Alicia; Ilacqua, Nicolo; Lamothe, Jennifer; Citron, Yemima R.; Gelinas, Yves; Gobeil, Stephane; Zoncu, Roberto; Caron, Alexandre; Morissette, Mathieu; Pellegrini, Luca; Rochette, Patrick J.; Estall, Jennifer L.; Efeyan, Alejo; Shum, Michael; Audet-Walsh, Etienne; Barbier, Olivier; Marette, Andre; Laplante, Mathieu
Differential acquisition of extracellular lipid correlates with pancreatic cancer subtype and metastatic tropism
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Rademaker, Gilles; Hernandez, Grace A.; Qiu, Longhui; Wen, Kwun W.; Jain, Aakriti; Kim, Grace A.; Zoncu, Roberto; Perera, Rushik M.
Emerging roles of the MiT/TFE factors in cancer
TRENDS IN CANCER
IF17.5
2023-10-017
PRE
Zoncu, Roberto; Perera, Rushika M.
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease (vol 24, pg 857, 2023)

mTORC1在代谢调节和疾病中营养感知和信号传导的分子基础 (第24卷，857页，2023)

NATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
2023-09-263
OA
Goul, Claire; Peruzzo, Roberta; Zoncu, Roberto
The molecular basis of nutrient sensing and signalling by mTORC1 in metabolism regulation and disease

mTORC1在代谢调节和疾病中营养感知和信号传导的分子基础

NATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
2023-08-2332
PRE
Goul, Claire; Peruzzo, Roberta; Zoncu, Roberto
PITTching in for lysosome repair
DEVELOPMENTAL CELL
IF8.7
2022-10-012
OA
Goul, Claire S.; Zoncu, Roberto
Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation

Mit-tfe底物选择性mTORC1调控中FLCN RagC间隙激活的结构基础

SCIENCE ADVANCES
IF12.5
2022-09-1612
OAAI
Jansen, Rachel M.; Peruzzo, Roberta; Fromm, Simon A.; Yokom, Adam L.; Zoncu, Roberto; Hurley, James H.
Built to last: lysosome remodeling and repair in health and disease
TRENDS IN CELL BIOLOGY
IF18.1
2022-07-0132
OAAI
Zoncu, Roberto; Perera, Rushika M.
Organelle transporters and inter-organelle communication as drivers of metabolic regulation and cellular homeostasis
MOLECULAR METABOLISM
IF6.6
2022-06-0143
OAAI
Jain, Aakriti; Zoncu, Roberto
Picking the arginine lock on PQLC2 cycling
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-08-270
OA
Jain, Aakriti; Zoncu, Roberto
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
NATURE CELL BIOLOGY
IF19.1
2021-03-0842
OAAI
Gupta, Suprit; Yano, Julian; Mercier, Vincent; Htwe, Htet Htwe; Shin, Hijai R.; Rademaker, Gilles; Cakir, Zeynep; Ituarte, Thomas; Wen, Kwun W.; Kim, Grace E.; Zoncu, Roberto; Roux, Aurelien; Dawson, David W.; Perera, Rushika M.
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

NPC1-mTORC1信号传导将胆固醇感应与细胞器稳态耦合，并且是C型niemann-pick的可靶向途径

DEVELOPMENTAL CELL
IF8.7
2021-02-01115
OAAI
Davis, Oliver B.; Shin, Hijai R.; Lim, Chun-Yan; Wu, Emma Y.; Kukurugya, Matthew; Maher, Claire F.; Perera, Rushika M.; Ordonez, M. Paulina; Zoncu, Roberto
4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor
JOURNAL OF LIPID RESEARCH
IF4.1
2021-01-0116
OAAI
Moldavski, Ofer; Zushin, Peter-James H.; Berdan, Charles A.; Van Eijkeren, Robert J.; Jiang, Xuntian; Qian, Mingxing; Ory, Daniel S.; Covey, Douglas F.; Nomura, Daniel K.; Stahl, Andreas; Weiss, Ethan J.; Zoncu, Roberto
The Lysosome at the Intersection of Cellular Growth and Destruction
DEVELOPMENTAL CELL
IF8.7
2020-07-0179
OAAI
Shin, Hijai R.; Zoncu, Roberto
Lysosomal recycling of amino acids affects ER quality control
SCIENCE ADVANCES
IF12.5
2020-06-2620
OAAI
Higuchi-Sanabria, Ryo; Shen, Koning; Kelet, Naame; Frankino, Phillip A.; Durieux, Jenni; Bar-Ziv, Raz; Sing, Cierra N.; Garcia, Enrique J.; Homentcovschi, Stefan; Sanchez, Melissa; Wu, Rui; Tronnes, Sarah U.; Joe, Larry; Webster, Brant; Ahilon-Jeronimo, Alex; Monshietehadi, Samira; Dallarda, Sofia; Pender, Corinne; Pon, Liza A.; Zoncu, Roberto; Dillin, Andrew

研究方向

暂未获取到该数据
R
Rushika M. Perera
H 指数:38论文数:88被引数:1.1万
D
David M. Sabatini
H 指数:149论文数:533被引数:15.4万
H
Hijai R. Shin
H 指数:15论文数:34被引数:2,008
D
Derek Toomre
H 指数:54论文数:194被引数:1.7万
J
James H. Hurley
H 指数:93论文数:417被引数:3.6万
A
Alejo Efeyan
H 指数:32论文数:91被引数:1.2万
D
Daniel K. Nomura
H 指数:80论文数:293被引数:2.5万
P
Pietro De Camilli
H 指数:146论文数:565被引数:6.9万
J
Julia Richter
H 指数:53论文数:241被引数:3.0万
R
Roberta Peruzzo
H 指数:18论文数:34被引数:1,012