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N

Nader Sanai

St. Joseph's Hospital and Medical Center

61H指数
383论文数
1.8W被引数
收录论文 154
发表时间
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Plasma 4β-Hydroxycholesterol Predicts Ribociclib CYP3A-Mediated Metabolism, but Not Plasma Exposure, in Patients with Primary Brain Cancer血浆4β-羟基胆固醇预测原发性脑癌患者中瑞博西尼经CYP3A介导的代谢，但并非其血浆暴露
errCancers
IF4.4
err2026-08-28
err0
errOAAI
errCharuka Wickramasinghe; Xun Bao; Yuanyuan Jiang; Jun Jiang; Yang Yue; Nader Sanai; Jing Li
err分享
err收藏
Disrupted Transporter Protein Expression and Cell-Specific Localization Reveal Neurovascular Unit Remodeling in Human Glioblastoma破坏的转运蛋白表达和细胞特异性定位揭示了人类胶质母细胞瘤中神经血管单元的重塑
errNeuro-Oncology Advances
IF4.1
err2026-03-11
err0
errOAAI
errXun Bao; Yuanyuan Jiang; Beth Hermes; Nader Sanai; Jing Li; null
err分享
err收藏
An early clinical trial of 5-ALA sonodynamic therapy in recurrent high-grade glioma5-ALA声动力疗法在复发性高级别胶质瘤中的早期临床试验
errScience Translational Medicine
IF14.6
err2025-11-26
err0
PREAI
errNader Sanai; Artak Tovmasyan; An-Chi Tien; Yu-Wei Chang; Tigran Margaryan; William Knight; Kristin Hendrickson; Jennifer Eschbacher; Jocelyn Harmon; Amy Hong; Wonsuk Yoo; Charuta Furey; Stuart L. Marcus; Lea Alhilali; Igor Barani; Zaman Mirzadeh; Shwetal Mehta
err分享
err收藏
Single-nucleus transcriptomics, pharmacokinetics, and pharmacodynamics of CDK4/6 and mTOR inhibition in a Phase 0/1 trial of recurrent high-grade glioma单核转录组学、药代动力学和药效动力学：CDK4/6和mTOR抑制在复发性高级别胶质瘤的0/1期临床试验中
errNeuro-Oncology
IF13.4
err2025-11-08
err0
errOAAI
errKevin C Johnson; An-Chi Tien; Jun Jiang; James McNamara; Yu-Wei Chang; Chelsea Montgomery; Anita DeSantis; Leonel Elena-Sanchez; Yoko Fujita; Seongho Kim; Avishay Spitzer; Paul Gabriel; William F Flynn; Elise T Courtois; Amy Hong; Jocelyn Harmon; Yoshie Umemura; Artak Tovmasyan; Jing Li; Shwetal Mehta; Roel G W Verhaak; Nader Sanai; null
err分享
err收藏
HDAC inhibition-induced neuronal-like state creates cytoskeletal vulnerabilities in glioblastomaHDAC抑制诱导的神经元样状态会引发胶质母细胞瘤的细胞骨架脆弱性
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errYangi, Doga Demir; Orndorff, Keely; Prakash, Nithish; Uzunalli, Gozde; Stavnichuk, Mariya; Patel, Sonam; Sanai, Nader; Mehta, Shwetal
err分享
err收藏
EVALUATION OF TEAD INHIBITOR, VT3989, TREATMENT IN AGGRESSIVE MENINGIOMATEAD抑制剂VT3989在侵袭性脑膜瘤中的治疗效果评估
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errDesai, Siddhi; McNamara, James; Salisbury, Nicole; Stavnichuk, Mariya; Hayes, Elizabeth; Shivanna, Anilkumar Thaghalli; Patel, Sonam; Fakhoury, Jordan; Sanai, Nader; Tien, An-Chi; Mehta, Shwetal
err分享
err收藏
Diverse redox states underpin glioblastoma heterogeneity in preclinical models and patient samples不同的氧化还原状态是前临床模型和患者样本中胶质母细胞瘤异质性的基础
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errPatel, Sonam; Margaryan, Tigran; Zhang, Hualin; Shaik, Kamal; Knight, William; Pham, Brian; Stavnichuk, Mariya; Hayes, Elizabeth; Kelley-Wolfe, Kyria; Brownell, Zackariah; Hon, Ruiheng; He, Xu; Chung, Kaitlyn; Sanai, Nader; Mehta, Shwetal; Tien, An-Chi; Tovmasyan, Artak
err分享
err收藏
INTEGRATED PHARMACOKINETICS, PHARMACODYNAMICS, AND CLINICAL DATA UPDATE FROM PHASE 0/1 TRIAL FOR BDTX-1535 IN NEWLY-DIAGNOSED AND RECURRENT GLIOBLASTOMA PATIENTS WITH EGFR ALTERATIONSBDTX-1535在EGFR突变的新诊断和复发胶质母细胞瘤患者中，来自第0/1期试验的整合药代动力学、药效学和临床数据更新
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errSanai, Nader; Umemura, Yoshie; Karapetyan, Vahuni; Margaryan, Tigran; Huttenlocher, Dylan; Pham, Brian; Harmon, Jocelyn; Hong, Amy; Tien, An-Chi; Tovmasyan, Artak; Mehta, Shwetal
err分享
err收藏
A comprehensive framework for intraoperative mapping and monitoring, and perioperative neurological, linguistic, and outcome assessment in glioma resection: Consensus recommendations from the PIONEER Consortium and RANO resect group胶质瘤切除术中的综合框架：包括术中定位与监测、围手术期神经功能、语言功能及预后评估，PIONEER Consortium 和 RANO resect group 共识建议
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errGerritsen, Jasper; Karschnia, Philipp; Bello, Lorenzo; Hervey-Jumper, Shawn; Young, Jacob; Seidel, Kathleen; Satoer, Djaina; Schnell, Oliver; Parsons, Michael; Nahed, Brian; Menna, Grazia; Teske, Nico; Smith, Timothy; Sanai, Nader; Krieg, Sandro; Schucht, Philippe; Broekman, Marike; De Vleeschouwer, Steven; Jakola, Asgeir; Van Den Bent, Martin; Chang, Susan; Vogelbaum, Michael; Vincent, Arnaud; Tonn, Joerg-Christian; Berger, Mitchel
err分享
err收藏
The radioprotective effect of a novel brain-penetrant superoxide dismutase mimic on normal brain一种新型脑穿透性超氧化物歧化酶模拟物对正常脑组织的辐射防护作用
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errZhang, Hualin; Kaplan, Gerold; Molloy, Jennifer; Lexvold, Riley; Sanai, Nader; Mehta, Shwetal; Tien, An-Chi; Tovmasyan, Artak
err分享
err收藏
SINGLE-CELL PROFILING REVEALS CELLULAR DIVERSITY AND A STEM-LIKE COMPARTMENT IN SUBEPENDYMOMA单细胞分析揭示了室管膜下瘤中的细胞多样性及类干细胞结构域。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errLewis, Erika; Furey, Charuta; Johnson, Kevin; Chung, Kaitlyn; Amin, Samir; Gandhi, Sirin; Rabah, Nicholas; Asher, Anthony; Rabadi, Inad; Fakhoury, Jordan; Tien, An-Chi; Verhaak, Roel; Mehta, Shwetal; Sanai, Nader
err分享
err收藏
A phase 0/1 study of PRMT5 inhibitor BMS-986504 in recurrent glioblastoma participants with MTAP deletion一项关于PRMT5抑制剂BMS-986504在MTAP缺失的复发性胶质母细胞瘤患者中的I期研究
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
PREAI
errSanai, Nader; Umemura, Yoshie; Knight, William; Gonzalez, Nadia; Kandasamy, Murugesh; Zhang, Hualin; Pham, Brian; Harmon, Jocelyn; Hong, Amy; Tien, An-Chi; Tovmasyan, Artak; Mehta, Shwetal
err分享
err收藏
A global, open-label, randomized Phase 3 trial evaluating niraparib compared to standard temozolomide therapy in patients with newly diagnosed, MGMT-unmethylated glioblastoma一项全球、开放标签、随机III期临床试验，评估尼拉帕利与标准替莫唑胺疗法在 newly diagnosed、MGMT-unmethylated glioblastoma 患者中的比较。
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errSanai, Nader; Mehta, Shwetal; Tien, An-Chi; Tovmasyan, Artak; Harmon, Jocelyn; Kennedy, William; Aziez, Amine; Chalmers, Anthony; Khasraw, Mustafa; Lim-Fat, Mary Jane; Minniti, Guiseppe; Sanchez, Juan-Manuel Sepulveda; Touat, Mehdi; Umemura, Yoshie
err分享
err收藏
P12.27.B A PHASE 0/1 STUDY OF PRMT5 INHIBITOR BMS-986504 IN RECURRENT GLIOBLASTOMA PARTICIPANTS WITH MTAP DELETED TUMORS.P12.27.B MTAP缺失肿瘤复发性胶质母细胞瘤患者中PRMT5抑制剂BMS-986504的0/1期研究。
errNeuro-Oncology
IF13.4
err2025-10-03
err0
errOAAI
errN Sanai; Y Umemura; W Knight; M Kandasamy; H Zhang; B Pham; J Harmon; A Hong; A Tien; A Tovmasyan; S Mehta
err分享
err收藏
DETERMINATION OF TOTAL AND UNBOUND LEVELS OF A POTENT WEE1 INHIBITOR, ZN-C3, IN HUMAN PLASMA, CSF, AND BRAIN TUMOR BY A VALIDATED LC-MS/MS METHOD.通过验证的LC-MS/MS方法测定强效WEE1抑制剂ZN-C3在人体血浆、脑脊液和脑肿瘤中的总浓度和未结合浓度。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errKaplan, G. S.; Margaryan, T.; Sanai, N.; Mehta, S.; Tovmasyan, A.
err分享
err收藏
PHARMACOKINETICS, PHARMACODYNAMICS AND CLINICAL DATA UPDATE FROM PHASE 0/1 TRIAL FOR BDTX-1535 IN RECURRENT GLIOBLASTOMA PATIENTS WITH EGFR ALTERATIONS.BDTX-1535在EGFR发生变异的复发性胶质母细胞瘤患者中，来自第0/1期试验的药代动力学、药效动力学及临床数据更新。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSanai, N.; Umemura, Y.; Karapetyan, V; Margaryan, T.; Huttenlocher, D.; Pham, B.; Harmon, J.; Hong, A.; Yoo, W.; Tien, A.; Tovmasyan, A.; Mehta, S.
err分享
err收藏
A CLINICAL UPDATE OF A FIRST-IN-HUMAN PHASE 0/1 TRIAL OF 5-AMINOLEVULINIC ACID SONODYNAMIC THERAPY (5-ALA SDT) IN RECURRENT GLIOBLASTOMA.5-氨基乙酰丙酸声动力疗法(5-ALA SDT)在复发性胶质母细胞瘤中的首个人类临床试验0/1期临床更新。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSanai, N.; Tien, A.; Tovmasyan, A.; Chang, Y.; Margaryan, T.; Hendrickson, K.; Eschbacher, J.; Yoo, W.; Harmon, J.; Hong, A.; Quarles, C.; Alhilali, L.; Barani, I; Mirzadeh, Z.; Mehta, S.
err分享
err收藏
A MECHANISMS OF RADIOSENSITIZATION AND RESISTANCE FOLLOWING HDAC INHIBITION IN GBM PRECLINICAL MODELS.HDAC抑制剂在GBM临床前模型中放射增敏和抵抗的机制。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
PREAI
errHisted, S.; Orndorff, K.; Yangi, D.; Chung, K.; Hayes, E.; Kelley-Wolfe, K.; Pham, B.; Uzunalli, G.; Patel, S.; Sanai, N.; Tien, A.; Tovmasyan, A.; Mehta, S.
err分享
err收藏
A GLOBAL PHASE 3, OPEN-LABEL, RANDOMIZED-CONTROLLED STUDY FOR NEWLY-DIAGNOSED, MGMT UNMETHYLATED GLIOBLASTOMA, COMPARING NIRAPARIB VS STANDARD OF CARE TEMOZOLOMIDE TREATMENT.一项全球性III期、开放标签、随机对照研究，针对新诊断的MGMT未甲基化胶质母细胞瘤，比较Niraparib与标准护理替莫唑胺治疗。
errNEURO-ONCOLOGY
IF13.4
err2025-10-01
err0
errOAAI
errSanai, N.; Mehta, S.; Tien, A.; Tovmasyan, A.; Harmon, J.; Kennedy, W. R.; Aziez, A.; Chalmers, A.; Khasraw, M.; Lim Fat, M.; Minniti, G.; Sepulveda, J. M.; Touat, M.; Umemura, Y.
err分享
err收藏
Population Pharmacokinetic Modeling of Total and Unbound Pamiparib in Glioblastoma Patients: Insights into Drug Disposition and Dosing Optimization胶质瘤患者中帕米帕利总药量和游离药量的群体药代动力学建模：药物处置及给药方案优化的见解
errPHARMACEUTICS
IF5.5
err2025-04-16
err0
errOAAI
errWickramasinghe, Charuka; Kim, Seongho; Jiang, Yuanyuan; Bao, Xun; Yue, Yang; Jiang, Jun; Hong, Amy; Sanai, Nader
err分享
err收藏

研究方向

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合作学者
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李晶 (Jing Li)
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