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收藏分享 收藏 Loss of Socs2 improves molecular responses to IFNα in a mouse model of myeloproliferative neoplasms driven by JAK2-V617F在由JAK2-V617F驱动的骨髓增殖性肿瘤小鼠模型中，Socs2的缺失改善了IFNα的分子应答。
Usart, Marc; Kimmerlin, Quentin; Stetka, Jan; Stoll, Cedric; Rai, Shivam; Fonseca, Tiago Almeida; Karjalainen, Riikka; Hao-Shen, Hui; Roux, Julien; El Taher, Athimed; Lynch, Dylan; Makukhin, Nikolai; Ciulli, Alessio; Skoda, Radek C. 分享 收藏 Identification of Hepatic-like Erythropoietin with Enhanced Activity As a New Cause of Hereditary and Acquired Erythrocytosis鉴定具有增强活性的肝样促红细胞生成素作为遗传性和获得性红细胞增多症的新病因Martin, Laurent; Maric, Darko; Idriss, Salam; Delamare, Marine; Le Roy, Amandine; Maaziz, Nada; Caillaud, Amandine; Si-Tayeb, Karim; Robriquet, Florence; Lenglet, Marion; Erceau, Lucie; Bellanne-Chantelot, Christine; Plo, Isabelle; Aral, Bernard; Garrec, Celine; Airaud, Fabrice; Gianfermi, Clara; Antunes, Vincent; Keppner, Anna; Vincent, Sarah Mathilda; Desfontaine, Alexis; Mode, Nina; Laporte, Fabien; Gaignerie, Anne; Chariau, Caroline; Leray, Isabelle; Rogue, Coline; David, Laurent; Redon, Richard; Bezieau, Stephane; Mansour, Lamisse; Galacteros, Frederic; Maillet, Thibault; Pasquet, Marlene; Cougoul, Pierre; Nloga, Anne-Marie; Gardin, Claude; Guitton, Corinne; Dubruille, Viviane; Giacobbi-Milet, Vannina; Leblanc, Thierry; Kaya, Zuhre; Semama, Denis; James, Chloe; Carillo, Serge; Ochmann, Marlene; Waage, Anders; Mortier, Erwan; Maillasson, Mike; Quemener, Agnes; Cario, Holger; Skoda, Radek C.; Zermati, Yael; Hoogewijs, David; Marchand, Alexandre; Girodon, Francois; Gardie, Betty 分享 收藏 Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fateSchaefer, Thorsten; Mittal, Nitish; Wang, Hui; Ataman, Meric; Candido, Silvia; Lotscher, Jonas; Velychko, Sergiy; Tintignac, Lionel; Bock, Thomas; Borsch, Anastasiya; Bassler, Jochen; Rao, Tata Nageswara; Zmajkovic, Jakub; Roffeis, Sarah; Loliger, Jordan; Jacob, Francis; Dumlin, Alain; Schurch, Christoph; Schmidt, Alexander; Skoda, Radek C.; Wymann, Matthias P.; Hess, Christoph; Schoeler, Hans R.; Zaehres, Holm; Hurt, Ed; Zavolan, Mihaela; Lengerke, Claudia 分享 收藏 分享 收藏 The glutaminase inhibitor CB-839 targets metabolic dependencies of JAK2-mutant hematopoiesis in MPNUsart, Marc; Hansen, Nils; Stetka, Jan; Fonseca, Tiago Almeida; Guy, Alexandre; Kimmerlin, Quentin; Rai, Shivam; Hao-Shen, Hui; Roux, Julien; Dirnhofer, Stefan; Skoda, Radek C. 分享 收藏 Redefining SOX2 as a bifunctional mediator of transcription and adjusted translation controlMittal, Nitish; Ataman, Meric; Wang, Hui; Candido, Silvia; Lotscher, Jonas; Velychko, Sergiy; Tintignac, Lionel; Bock, Thomas; Borsch, Anastasiya; Bassler, Jochen; Rao, Tata Nageswara; Zmajkovic, Jakub; Roffeis, Sarah; Loliger, Jordan; Jacob, Francis; Dumlin, Alain; Schurch, Christoph; Schmidt, Alexander; Skoda, Radek C.; Hess, Christoph; Scholer, Hans R.; Zaehres, Holm; Hurt, Ed; Zavolan, Mihaela; Lengerke, Claudia; Schaefer, Thorsten 分享 收藏 IL-1 3 promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cellsRai, Shivam; Zhang, Yang; Grockowiak, Elodie; Kimmerlin, Quentin; Hansen, Nils; Stoll, Cedric B.; Usart, Marc; Paz, Damien Luque; Hao-Shen, Hui; Zhu, Yexuan; Roux, Julien; Bader, Michael S.; Dirnhofer, Stefan; Farady, Christopher J.; Schroeder, Timm; Mendez-Ferrer, Simon; Skoda, Radek C. 分享 收藏 Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosisWildschut, Mattheus H. E.; Mena, Julien; Dordelmann, Cyril; van Oostrum, Marc; Hale, Benjamin D.; Settelmeier, Jens; Festl, Yasmin; Lysenko, Veronika; Schurch, Patrick M.; Ring, Alexander; Severin, Yannik; Bader, Michael S.; Pedrioli, Patrick G. A.; Goetze, Sandra; van Drogen, Audrey; Balabanov, Stefan; Skoda, Radek C.; Lopes, Massimo; Wollscheid, Bernd; Theocharides, Alexandre P. A.; Snijder, Berend 分享 收藏 Impact of Clonal Architecture on Clinical Course and Prognosis in Patients With Myeloproliferative NeoplasmsPaz, Damien Luque; Bader, Michael S.; Nienhold, Ronny; Rai, Shivam; Fonseca, Tiago Almeida; Stetka, Jan; Hao-Shen, Hui; Mild-Schneider, Gabriele; Passweg, Jakob R.; Skoda, Radek C. 分享 收藏 Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm抑制白介素-1β 可减轻JAK2-V617F驱动的骨髓增殖性肿瘤小鼠的骨髓纤维化和骨硬化Rai, Shivam; Grockowiak, Elodie; Hansen, Nils; Paz, Damien Luque; Stoll, Cedric B.; Hui Hao-Shen; Mild-Schneider, Gabriele; Dirnhofer, Stefan; Farady, Christopher J.; Mendez-Ferrer, Simon; Skoda, Radek C. 分享 收藏 Real-world study of children and young adults with myeloproliferative neoplasms: identifying risks and unmet needsSobas, Marta; Kiladjian, Jean-Jacques; Beauverd, Yan; Curto-Garcia, Natalia; Sadjadian, Parvis; Shih, Lee Yung; Devos, Timothy; Krochmalczyk, Dorota; Galli, Serena; Bieniaszewska, Maria; Seferynska, Ilona; McMullin, Mary Frances; Armatys, Anna; Spalek, Adrianna; Waclaw, Joanna; Zdrenghea, Mihnea; Legros, Laurence; Girodon, Francois; Lewandowski, Krzysztof; Figueras, Anna Angona; Samuelsson, Jan; Blanco, Aitor Abuin; Cony-Makhoul, Pascale; Collins, Angela; James, Chloe; Kusec, Rajko; Lauermannova, Marie; Noya, Maria Sol; Skowronek, Malgorzata; Szukalski, Lukasz; Szmigielska-Kaplon, Anna; Wondergem, Marielle; Dudchenko, Iryna; Tybor, Joanna Gora; Laribi, Kamel; de Nalecz, Anna Kulikowska; Demory, Jean-Loup; Le Du, Katell; Zweegman, Sonja; Raebel, Carlos Besses; Skoda, Radek; Giraudier, Stephane; Griesshammer, Martin; Harrison, Claire N.; Ianotto, Jean-Christophe 分享 收藏 分享 收藏 分享 收藏 The EHA Research Roadmap: Malignant Myeloid DiseasesDoehner, Hartmut; Malcovati, Luca; Ossenkoppele, Gert J.; Hochhaus, Andreas; Vannucchi, Alessandro Maria; Bullinger, Lars; Cervantes, Francisco; Craddock, Charles; de Witte, Theo; Doehner, Konstanze; Dombret, Herve; Fenaux, Pierre; Geissler, Jan; Germing, Ulrich; Guilhot, Francois; Harrison, Claire; Hellstrom-Lindberg, Eva; Passamonti, Francesco; Sierra, Jorge; Skoda, Radek; Wierzbowska, Agnieszka 分享 收藏 Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions血液学2021中的精准医学: 定义、工具、观点和开放性问题Valent, Peter; Orfao, Alberto; Kubicek, Stefan; Staber, Philipp; Haferlach, Torsten; Deininger, Michael; Kollmann, Karoline; Lion, Thomas; Virgolini, Irene; Winter, Georg; Hantschel, Oliver; Kenner, Lukas; Zuber, Johannes; Grebien, Florian; Moriggl, Richard; Hoermann, Gregor; Hermine, Olivier; Andreeff, Michael; Bock, Christoph; Mughal, Tariq; Constantinescu, Stefan N.; Kralovics, Robert; Sexl, Veronika; Skoda, Radek; Superti-Furga, Giulio; Jaeger, Ulrich 分享 收藏 分享 收藏 Longitudinal Cytokine Profiling Identifies GRO-α and EGF as Potential Biomarkers of Disease Progression in Essential ThrombocythemiaObro, Nina F.; Grinfeld, Jacob; Belmonte, Miriam; Irvine, Melissa; Shepherd, Mairi S.; Rao, Tata Nageswara; Karow, Axel; Riedel, Lisa M.; Harris, Oliva B.; Baxter, E. Joanna; Nangalia, Jyoti; Godfrey, Anna; Harrison, Claire N.; Li, Juan; Skoda, Radek C.; Campbell, Peter J.; Green, Anthony R.; Kent, David G. 分享 收藏 Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic TransformationEZH2的丧失重新编程BCAA代谢以驱动白血病转化Gu, Zhimin; Liu, Yuxuan; Cai, Feng; Patrick, McKenzie; Zmajkovic, Jakub; Cao, Hui; Zhang, Yuannyu; Tasdogan, Alpaslan; Chen, Mingyi; Qi, Le; Liu, Xin; Li, Kailong; Lyu, Junhua; Dickerson, Kathryn E.; Chen, Weina; Ni, Min; Merritt, Matthew E.; Morrison, Sean J.; Skoda, Radek C.; DeBerardinis, Ralph J.; Xu, Jian 分享 收藏 
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