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C

Christine L. Gee

Howard Hughes Medical Institute

H指数:25

被引数:3,230

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Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome

两种ATP酶亚基的底物相互作用孔环决定了26S蛋白酶体的降解效率

Nature Communications

IF15.7

2026-03-240

OAAI

Stimulated protein degradation to promote mitochondrial function and neuronal survival

通过诱导蛋白降解促进线粒体功能和神经元存活

IF45.8

2026-01-010

OA

Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1

26S蛋白酶体降解过程中的结构景观揭示了TXNL1的构象特异性结合

Nature Structural & Molecular Biology

IF10.1

2025-11-060

OAAI

NUB1 traps unfolded FAT10 for ubiquitin-independent degradation by the 26S proteasome

NUB1通过26S蛋白酶体捕获未折叠的FAT10，使其发生不依赖泛素化的降解。

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2025-04-110

OA

Reactive oxygen species control protein degradation at the mitochondrial import gate

活性氧控制线粒体进口门的蛋白质降解

IF16.6

2024-12-010

PRE

Mechanisms and regulation of substrate degradation by the 26S proteasome

26s蛋白酶体降解底物的机制和调控

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2024-10-030

PRE

Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2024-01-041

OA

Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo

NATURE CHEMISTRY

IF20.2

2023-06-0118

OAAI

Temporal and spatial resolution of distal protein motions that activate hydrogen tunneling in soybean lipoxygenase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-03-0319

OAAI

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-07-3032

OAAI

Leurs, Ulrike; Klein, Anders B.; McSpadden, Ethan D.; Griem-Krey, Nane; Solbak, Sara M. O.; Houlton, Josh; Villumsen, Inge S.; Vogensen, Stine B.; Hamborg, Louise; Gauger, Stine J.; Palmelund, Line B.; Larsen, Anne Sofie G.; Shehata, Mohamed A.; Kelstrup, Christian D.; Olsen, Jesper, V; Bach, Anders; Burnie, Robert O.; Kerr, D. Steven; Gowing, Emma K.; Teurlings, Selina M. W.; Chi, Chris C.; Gee, Christine L.; Frolund, Bente; Kornum, Birgitte R.; van Woerden, Geeske M.; Clausen, Rasmus P.; Kuriyan, John; Clarkson, Andrew N.; Wellendorph, Petrine

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

NATURE COMMUNICATIONS

IF15.7

2019-04-2925

OAAI

Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The Undoing of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2019-01-1522

OAAI

Influence of ageing on glass and resin bonding of dental glass-ceramic veneer adhesion to zirconia: A fracture mechanics analysis and interpretation

老化对牙科玻璃陶瓷贴面与氧化锆的玻璃和树脂粘合的影响: 断裂力学分析和解释

ACTA BIOMATERIALIA

IF9.6

2018-07-014

PREAI

Deconstruction of the Ras switching cycle through saturation mutagenesis

IF0

2017-07-0795

OAAI

Molecular mechanism of activation-triggered subunit exchange in Ca2+/ calmodulin-dependent protein kinase II

IF0

2016-03-0792

PRE

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2014-05-1975

OA

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

BIOCHEMICAL JOURNAL

IF4.3

2013-12-20241

OAAI

The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-12-13115

OAAI

A Phosphorylated Pseudokinase Complex Controls Cell Wall Synthesis in Mycobacteria

SCIENCE SIGNALING

IF6.6

2012-01-24151

OA

Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity

BIOCHEMICAL JOURNAL

IF4.3

2009-08-2726

OAAI