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T

Tobias C. Walther

Harvard University
H指数:75
被引数:3.1万

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Partial Loss of FITM2 Function Causes Hereditary Spastic Paraplegia

<i>FITM2</i>功能部分缺失导致遗传性痉挛性截瘫

Human Mutation
IF3.7
2026-10-230
OA
Ainara Salazar-Villacorta; Laura M. Bond; Leehyeon Kim; Katherine Anagnostopoulou; Annarita Scardamaglia; Eugenia Filippakopoulou; Athina Ververi; Stephanie Efthymiou; Argirios Dinopoulos; David Murphy; Chrisoula Kartanou; Dimitrios M. Vrachnos; Theodoros Loupis; Perilikis Makrythanasis; Leonidas Stefanis; Georgia Karadima; Georgios Koutsis; Marios Kaliakatsos; Henry Houlden; Tobias C. Walther; Robert V. Farese
Carboxyl-terminal blockade of sortilin binding enhances progranulin gene therapy in a mouse model of frontotemporal dementia

-sortilin结合的羧基末端阻断增强了小鼠额颞叶痴呆模型中的progranulin基因治疗

Science Translational Medicine
IF14.6
2026-08-190
PRE
Shreya N. Kashyap; Stephanie N. Fox; Vivianna R. DeNittis; Katherine I. Wilson; Nicholas R. Boyle; Mary Bullock; Aniketh S. Tadepalli; Stephanie R. Miller; Jorge J. Palop; Yohannes A. Ambaw; Tobias C. Walther; Robert V. Farese; Charles F. Murchison; Andrew E. Arrant; Erik D. Roberson
The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway

APOE3基因中的R136S突变通过抑制cGAS-STING-IFN通路赋予对tau病理的抵抗力。

Immunity
IF26.3
2025-06-230
PRE
Sarah Naguib; Chloe Lopez-Lee; Eileen Ruth Torres; Se-In Lee; Jingjie Zhu; Daphne Zhu; Pearly Ye; Kendra Norman; Mingrui Zhao; Man Ying Wong; Yohannes A. Ambaw; Rodrigo Muñoz-Castañeda; Wei Wang; Tark Patel; Maitreyee Bhagwat; Rada Norinsky; Sue-Ann Mok; Tobias C. Walther; Robert V. Farese; Wenjie Luo; Subhash C. Sinha; Zhuhao Wu; Li Fan; Shiaoching Gong; Li Gan

研究方向

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R
Robert V. Farese
H 指数:110论文数:314被引数:4.8万
R
Romain Christiano
H 指数:19论文数:52被引数:3,083
F
Florian Fröhlich
H 指数:31论文数:106被引数:5,571
C
Chandramohan Chitraju
H 指数:20论文数:37被引数:2,882
N
Natalie Krahmer
H 指数:27论文数:74被引数:4,468
N
Nora Kory
H 指数:18论文数:36被引数:3,750
N
Niklas Mejhert
H 指数:43论文数:104被引数:8,475
M
Matthias Mann
H 指数:250论文数:1,444被引数:29.9万
S
Sebastian Boland
H 指数:18论文数:37被引数:1,671
P
Peter Walter
H 指数:118论文数:586被引数:6.5万