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H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours Dibitetto, Diego; Liptay, Martin; Vivalda, Francesca; Dogan, Huelya; Gogola, Ewa; Gonzalez Fernandez, Martin; Duarte, Alexandra; Schmid, Jonas A.; Decollogny, Morgane; Francica, Paola; Przetocka, Sara; Durant, Stephen T.; Forment, Josep V.; Klebic, Ismar; Siffert, Myriam; de Bruijn, Roebi; Kousholt, Arne N.; Marti, Nicole A.; Dettwiler, Martina; Sorensen, Claus S.; Tille, Jean-Christophe; Undurraga, Manuela; Labidi-Galy, Intidhar; Lopes, Massimo; Sartori, Alessandro A.; Jonkers, Jos; Rottenberg, Sven 分享 收藏
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Nuclear actin polymerization rapidly mediates replication fork remodeling upon stress by limiting PrimPol activity Palumbieri, Maria Dilia; Merigliano, Chiara; Gonzalez-Acosta, Daniel; Kuster, Danina; Krietsch, Jana; Stoy, Henriette; von Kanel, Thomas; Ulferts, Svenja; Welter, Bettina; Frey, Joel; Doerdelmann, Cyril; Sanchi, Andrea; Grosse, Robert; Chiolo, Irene; Lopes, Massimo 分享 收藏
Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency Chanou, Anna; Weiss, Matthias; Holler, Karoline; Sajid, Atiqa; Straub, Tobias; Krietsch, Jana; Sanchi, Andrea; Ummethum, Henning; Lee, Clare S. K.; Kruse, Elisabeth; Trauner, Manuel; Werner, Marcel; Lalonde, Maxime; Lopes, Massimo; Scialdone, Antonio; Hamperl, Stephan 分享 收藏
Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis Wildschut, Mattheus H. E.; Mena, Julien; Dordelmann, Cyril; van Oostrum, Marc; Hale, Benjamin D.; Settelmeier, Jens; Festl, Yasmin; Lysenko, Veronika; Schurch, Patrick M.; Ring, Alexander; Severin, Yannik; Bader, Michael S.; Pedrioli, Patrick G. A.; Goetze, Sandra; van Drogen, Audrey; Balabanov, Stefan; Skoda, Radek C.; Lopes, Massimo; Wollscheid, Bernd; Theocharides, Alexandre P. A.; Snijder, Berend 分享 收藏
Mcl-1 deficiency in murine livers leads to nuclear polyploidisation and mitotic errors: Implications for hepatocellular carcinoma Clerbaux, Laure-Alix; Cordier, Pierre; Desboeufs, Nina; Unger, Kristian; Leary, Peter; Semere, Gabriel; Boege, Yannick; Chan, Lap Kwan; Desdouets, Chantal; Lopes, Massimo; Weber, Achim 分享 收藏
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Excessive reactive oxygen species induce transcription-dependent replication stress Andrs, Martin; Stoy, Henriette; Boleslavska, Barbora; Chappidi, Nagaraja; Kanagaraj, Radhakrishnan; Nascakova, Zuzana; Menon, Shruti; Rao, Satyajeet; Oravetzova, Anna; Dobrovolna, Jana; Surendranath, Kalpana; Lopes, Massimo; Janscak, Pavel 分享 收藏
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Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids 转录复制冲突的直接可视化揭示了复制后的DNA:RNA杂种 Stoy, Henriette; Zwicky, Katharina; Kuster, Danina; Lang, Kevin S.; Krietsch, Jana; Crossley, Magdalena P.; Schmid, Jonas A.; Cimprich, Karlene A.; Merrikh, Houra; Lopes, Massimo 分享 收藏
Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming Jacobs, Kurt; Doerdelmann, Cyril; Krietsch, Jana; Gonzalez-Acosta, Daniel; Mathis, Nicolas; Kushinsky, Saul; Guarino, Estrella; Gomez-Escolar, Carmen; Martinez, Dolores; Schmid, Jonas A.; Leary, Peter J.; Freire, Raimundo; Ramiro, Almudena R.; Eischen, Christine M.; Mendez, Juan; Lopes, Massimo 分享 收藏
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MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression MDM2结合并泛素化PARP1以增强DNA复制叉进展 Giansanti, Celeste; Manzini, Valentina; Dickmanns, Antje; Dickmanns, Achim; Palumbieri, Maria Dilia; Sanchi, Andrea; Kienle, Simon Maria; Rieth, Sonja; Scheffner, Martin; Lopes, Massimo; Dobbelstein, Matthias 分享 收藏
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PrimPol-mediated repriming facilitates replication traverse of DNA interstrand crosslinks Gonzalez-Acosta, Daniel; Blanco-Romero, Elena; Ubieto-Capella, Patricia; Mutreja, Karun; Miguez, Samuel; Llanos, Susana; Garcia, Fernando; Munoz, Javier; Blanco, Luis; Lopes, Massimo; Mendez, Juan 分享 收藏
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