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B

Baki Topal

KU Leuven
H指数:50
被引数:9,384

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Integrated multi-omics identifies distinct macrophage alterations during progression of metabolic dysfunction-associated steatohepatitis

整合多组学分析揭示代谢功能障碍相关脂肪性肝炎进展过程中巨噬细胞的特异性改变

Nature Genetics
IF29
2026-05-180
OAAI
Markus Boesch; Seray Anak; Dania El Abyad; Tessa Ostyn; Asier Antoranz; Trieu My Van; Daniel Newhouse; Caitlyn Myers; Lukas Van Melkebeke; Jeremy Palmer; Najmeh Saffarzadeh; Jonathan Sai-Hong Chui; Rita Feio-Azevedo; Lena Smets; Gautam Shankar; Nikolina Dubroja Lakić; Paula Longás Calvo; Thierry Voet; James Clark; Simon Cockell; Matthias Lannoo; Ellen Deleus; Joris Jaekers; Halit Topal; Baki Topal; Kai Markus Schneider; Michele Vacca; Michael Allison; Mattias Ekstedt; Jerome Boursier; Elisabetta Bugianesi; Vlad Ratziu; Frederik De Smet; Bram Boeckx; Ann K. Daly; Jörn M. Schattenberg; Jef Verbeek; Francesca Bosisio; Diether Lambrechts; Tania Roskams; Carolin V. Schneider; Sven Francque; Hannelie Korf; Anetta Härtlova; Dina Tiniakos; Quentin M. Anstee; Schalk van der Merwe; Olivier Govaere
Progression-free survival for unresectable non-metastatic locally advanced pancreatic cancer after surgical microwave ablation plus durvalumab and tremelimumab: phase-2 non-randomized prospective clinical trial

不可切除的非转移性局部晚期胰腺癌在行手术治疗联合微波消融、durvalumab和tremelimumab后的无进展生存期：二期非随机前瞻性临床研究

Communications Medicine
IF6.3
2025-11-180
OAAI
Halit Topal; Tom Venken; Ayse Bassez; Gabriela Chiritescu; Eric Van Cutsem; Schalk van der Merwe; Diether Lambrechts; Baki Topal
Failure to Rescue After Resection of Perhilar Cholangiocarcinoma in an International Multicenter Cohort
ANNALS OF SURGICAL ONCOLOGY
IF3.5
2024-10-152
OAAI
Olthof, Pim B.; Bouwense, Stefan A. W.; Bednarsch, Jan; Dewulf, Maxime; Kazemier, Geert; Maithel, Shishir; Jarnagin, William R.; Aldrighetti, Luca; Roberts, Keith J.; Troisi, Roberto I.; Malago, Massimo M.; Lang, Hauke; Alikhanov, Ruslan; Ruzzenente, Andrea; Malik, Hassan; Charco, Ramon; Sparrelid, Ernesto; Pratschke, Johann; Cescon, Matteo; Nadalin, Silvio; Hagendoorn, Jeroen; Schadde, Erik; Hoogwater, Frederik J. H.; Schnitzbauer, Andreas A.; Topal, Baki; Lodge, Peter; Damink, Steven W. M. Olde; Neumann, Ulf P.; Koerkamp, Bas Groot; Perihilar Cholangiocarcinoma Collaboration Grp, F.
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancer

内在性温度升高促使脂质代谢向铁死亡逃逸和胰腺癌化疗耐药方向发展

NATURE COMMUNICATIONS
IF15.7
2024-10-020
OAAI
de Laat, Vincent; Topal, Halit; Spotbeen, Xander; Talebi, Ali; Dehairs, Jonas; Idkowiak, Jakub; Vanderhoydonc, Frank; Ostyn, Tessa; Zhao, Peihua; Jacquemyn, Maarten; Woelk, Michele; Sablina, Anna; Augustyns, Koen; Vanden Berghe, Tom; Roskams, Tania; Daelemans, Dirk; Fedorova, Maria; Topal, Baki; Swinnen, Johannes V.
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance

癌细胞中的核苷酸代谢促进了UDP驱动的巨噬细胞串扰，促进了免疫抑制和免疫治疗抵抗

NATURE CANCER
IF28.5
2024-06-067
OAAI
Scolaro, Tommaso; Manco, Marta; Pecqueux, Mathieu; Amorim, Ricardo; Trotta, Rosa; Van Acker, Heleen H.; Van Haele, Matthias; Shirgaonkar, Niranjan; Naulaerts, Stefan; Daniluk, Jan; Prenen, Fran; Varamo, Chiara; Ponti, Donatella; Doglioni, Ginevra; Ferreira Campos, Ana Margarida; Fernandez Garcia, Juan; Radenkovic, Silvia; Rouhi, Pegah; Beatovic, Aleksandar; Wang, Liwei; Wang, Yu; Tzoumpa, Amalia; Antoranz, Asier; Sargsian, Ara; Di Matteo, Mario; Berardi, Emanuele; Goveia, Jermaine; Ghesquiere, Bart; Roskams, Tania; Soenen, Stefaan; Voets, Thomas; Manshian, Bella; Fendt, Sarah-Maria; Carmeliet, Peter; Garg, Abhishek D.; Dasgupta, Ramanuj; Topal, Baki; Mazzone, Massimiliano
Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases

乳腺癌肝转移中组织病理学生长模式的转录组学特征

CLINICAL & EXPERIMENTAL METASTASIS
IF3.2
2024-03-290
OAAI
Leduc, Sophia; Nguyen, Ha-Linh; Richard, Francois; Zels, Gitte; Mahdami, Amena; De Schepper, Maxim; Maetens, Marion; Pabba, Anirudh; Jaekers, Joris; Latacz, Emily; Bohlok, Ali; Vanderheyden, Evy; Van Brussel, Thomas; Boeckx, Bram; Schepers, Rogier; Lambrechts, Diether; Dirix, Luc; Larsimont, Denis; Vankerckhove, Sophie; Lucidi, Valerio; Topal, Baki; Bachir, Imane; Donckier, Vincent; Floris, Giuseppe; Vermeulen, Peter; Desmedt, Christine
Higher Postoperative Mortality and Inferior Survival After Right-Sided Liver Resection for Perihilar Cholangiocarcinoma: Left-Sided Resection is Preferred When Possible
ANNALS OF SURGICAL ONCOLOGY
IF3.5
2024-03-129
OAAI
Olthof, Pim B.; Erdmann, Joris I.; Alikhanov, Ruslan; Charco, Ramon; Guglielmi, Alfredo; Hagendoorn, Jeroen; Hakeem, Abdul; Hoogwater, Frederik J. H.; Jarnagin, William R.; Kazemier, Geert; Lang, Hauke; Maithel, Shishir K.; Malago, Massimo; Malik, Hassan Z.; Nadalin, Silvio; Neumann, Ulf; Olde Damink, Steven W. M.; Pratschke, Johann; Ratti, Francesca; Ravaioli, Matteo; Roberts, Keith J.; Schadde, Erik; Schnitzbauer, Andreas A.; Sparrelid, Ernesto; Topal, Baki; Troisi, Roberto I.; Groot Koerkamp, Bas
Adipose tissue macrophage dysfunction is associated with a breach of vascular integrity in NASH
JOURNAL OF HEPATOLOGY
IF33
2024-03-014
OA
Boesch, Markus; Lindhorst, Andreas; Feio-Azevedo, Rita; Brescia, Paola; Silvestri, Alessandra; Lannoo, Matthias; Deleus, Ellen; Jaekers, Joris; Topal, Halit; Topal, Baki; Ostyn, Tessa; Wallays, Marie; Smets, Lena; Van Melkebeke, Lukas; Hartlova, Anetta; Roskams, Tania; Bedossa, Pierre; Verbeek, Jef; Govaere, Olivier; Francque, Sven; Sifrim, Alejandro; Voet, Thierry; Rescigno, Maria; Gericke, Martin; Korf, Hannelie; van der Merwe, Schalk
Histopathological growth patterns and tumor-infiltrating lymphocytes in breast cancer liver metastases

乳腺癌肝转移的组织病理学生长模式和肿瘤浸润淋巴细胞

NPJ BREAST CANCER
IF7.6
2023-12-153
OA
Leduc, Sophia; De Schepper, Maxim; Richard, Francois; Maetens, Marion; Pabba, Anirudh; Borremans, Kristien; Jaekers, Joris; Latacz, Emily; Zels, Gitte; Bohlok, Ali; Van Baelen, Karen; Nguyen, Ha Linh; Geukens, Tatjana; Dirix, Luc; Larsimont, Denis; Vankerckhove, Sophie; Santos, Eva; Oliveira, Rui Caetano; Dede, Kristof; Kulka, Janina; Borbala, Szekely; Salamon, Ferenc; Madaras, Lilla; Marcell Szasz, A.; Lucidi, Valerio; Meyer, Yannick; Topal, Baki; Verhoef, Cornelis; Engstrand, Jennie; Moro, Carlos Fernandez; Gerling, Marco; Bachir, Imane; Biganzoli, Elia; Donckier, Vincent; Floris, Giuseppe; Vermeulen, Peter; Desmedt, Christine
PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma
NATURE COMMUNICATIONS
IF15.7
2023-11-2911
OAAI
Cappuyns, Sarah; Philips, Gino; Vandecaveye, Vincent; Boeckx, Bram; Schepers, Rogier; Van Brussel, Thomas; Arijs, Ingrid; Mechels, Aurelie; Bassez, Ayse; Lodi, Francesca; Jaekers, Joris; Topal, Halit; Topal, Baki; Bricard, Orian; Qian, Junbin; Van Cutsem, Eric; Verslype, Chris; Lambrechts, Diether; Dekervel, Jeroen
Predicting futility of upfront surgery in perihilar cholangiocarcinoma: Machine learning analytics model to optimize treatment allocation
HEPATOLOGY
IF15.8
2023-08-0311
PRE
Ratti, Francesca; Marino, Rebecca; Olthof, Pim B.; Pratschke, Johann; Erdmann, Joris I.; Neumann, Ulf P.; Prasad, Raj; Jarnagin, William R.; Schnitzbauer, Andreas A.; Cescon, Matteo; Guglielmi, Alfredo; Lang, Hauke; Nadalin, Silvio; Topal, Baki; Maithel, Shishir K.; Hoogwater, Frederik J. H.; Alikhanov, Ruslan; Troisi, Roberto; Sparrelid, Ernesto; Roberts, Keith J.; Malago, Massimo; Hagendoorn, Jeroen; Malik, Hassan Z.; Damink, Steven W. M. Olde; Kazemier, Geert; Schadde, Erik; Charco, Ramon; de Reuver, Philip R.; Koerkamp, Bas Groot; Aldrighetti, Luca
Same-session double EUS-guided bypass versus surgical gastroenterostomy and hepaticojejunostomy: an international multicenter comparison

同期双EUS引导下旁路手术与外科胃肠吻合术和肝空肠吻合术: 国际多中心比较

GASTROINTESTINAL ENDOSCOPY
IF7.5
2023-08-019
OAAI
Bronswijk, Michiel; Vanella, Giuseppe; van Wanrooij, Roy L. J.; Samanta, Jayanta; Lauwereys, Jonas; Perez-Cuadrado-Robles, Enrique; Dell'Anna, Giuseppe; Dhar, Jahnvi; Gupta, Vikas; van Malenstein, Hannah; Laleman, Wim; Jaekers, Joris; Topal, Halit; Topal, Baki; Crippa, Stefano; Falconi, Massimo; Besselink, Marc G.; Messaoudi, Nouredin; Arcidiacono, Paolo Giorgio; Kunda, Rastislav; Van der Merwe, Schalk
Multivariable prediction model for both 90-day mortality and long-term survival for individual patients with perihilar cholangiocarcinoma: does the predicted survival justify the surgical risk?

肝门周围胆管癌患者90天死亡率和长期生存率的多变量预测模型: 预测生存率是否证明手术风险合理？

BRITISH JOURNAL OF SURGERY
IF8.7
2023-03-1516
OAAI
van Keulen, Anne-Marleen; Buettner, Stefan; Erdmann, Joris, I; Pratschke, Johann; Ratti, Francesca; Jarnagin, William R.; Schnitzbauer, Andreas A.; Lang, Hauke; Ruzzenente, Andrea; Nadalin, Silvio; Cescon, Matteo; Topal, Baki; Olthof, Pim B.; Koerkamp, Bas Groot
Histopathological and immune characterization of liver metastases from patients with breast cancer
CANCER RESEARCH
IF16.6
2023-03-010
PRE
Leduc, Sophia; De Schepper, Maxim; Vermeulen, Peter; Floris, Giuseppe; Biganzoli, Elia; Donckier, Vincent; Bohlok, Ali; Gerling, Marco; Richard, Francois; Maetens, Marion; Jaekers, Joris; Topal, Baki; Latacz, Emily; Van Baelen, Karen; Geukens, Tatjana; Nguyen, Ha Linh; Dirix, Luc; Larsimont, Denis; Van Kerckhove, Sophie; Oliveira, Rui Caetano; Kulka, Janina; Lucidi, Valerio; Meyer, Yannick; Verhoef, Cornelis; Santos, Eva; Salamon, Ferenc; Madaras, Lilla; Szasz, A. Marcell; Borbala, Szekely; Dede, Kristof; Engstrand, Jennie; Moro, Carlos Fernandez; Desmedt, Christine
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer

靶向碳酸氢盐转运蛋白SLC4A4克服了胰腺癌的免疫抑制和免疫治疗耐药性

NATURE CANCER
IF28.5
2022-12-1557
OAAI
Cappellesso, Federica; Orban, Marie-Pauline; Shirgaonkar, Niranjan; Berardi, Emanuele; Serneels, Jens; Neveu, Marie-Aline; Di Molfetta, Daria; Piccapane, Francesca; Caroppo, Rosa; Debellis, Lucantonio; Ostyn, Tessa; Joudiou, Nicolas; Mignion, Lionel; Richiardone, Elena; Jordan, Benedicte F.; Gallez, Bernard; Corbet, Cyril; Roskams, Tania; DasGupta, Ramanuj; Tejpar, Sabine; Di Matteo, Mario; Taverna, Daniela; Reshkin, Stephan J.; Topal, Baki; Virga, Federico; Mazzone, Massimiliano
Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

巨噬细胞清道夫受体1介导非酒精性脂肪性肝病中脂质诱导的炎症

JOURNAL OF HEPATOLOGY
IF33
2022-05-0181
OAAI
Govaere, Olivier; Petersen, Sine Kragh; Martinez-Lopez, Nuria; Wouters, Jasper; Van Haele, Matthias; Mancina, Rosellina M.; Jamialahmadi, Oveis; Bilkei-Gorzo, Orsolya; Lassen, Pierre Bel; Darlay, Rebecca; Peltier, Julien; Palmer, Jeremy M.; Younes, Ramy; Tiniakos, Dina; Aithal, Guruprasad P.; Allison, Michael; Vacca, Michele; Goransson, Melker; Berlinguer-Palmini, Rolando; Clark, James E.; Drinnan, Michael J.; Yki-Jarvinen, Hannele; Dufour, Jean-Francois; Ekstedt, Mattias; Francque, Sven; Petta, Salvatore; Bugianesi, Elisabetta; Schattenberg, Jorn M.; Day, Christopher P.; Cordell, Heather J.; Topal, Baki; Clement, Karine; Romeo, Stefano; Ratziu, Vlad; Roskams, Tania; Daly, Ann K.; Anstee, Quentin M.; Trost, Matthias; Hartlova, Anetta

研究方向

暂未获取到该数据
T
Tania Roskams
H 指数:100论文数:786被引数:3.7万
O
Olivier Govaere
H 指数:47论文数:169被引数:1.1万
R
Raymond Aerts
H 指数:45论文数:256被引数:8,778
C
Chris Verslype
H 指数:68论文数:710被引数:2.8万
F
Frederik Nevens
H 指数:89论文数:1,026被引数:3.3万
J
Joris Jaekers
H 指数:13论文数:52被引数:607
M
Mina Komuta
H 指数:40论文数:196被引数:7,411
J
Jacques Pirenne
H 指数:69论文数:1,093被引数:2.1万
G
Gregory Sergeant
H 指数:19论文数:70被引数:1,589
H
Halit Topal
H 指数:10论文数:61被引数:325