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D

Dean Clift

francis crick avenue

H指数:18

被引数:2,668

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State-selective small molecule degraders that preferentially remove aggregates and oligomers

选择性去除聚集物和寡聚物的状态选择性小分子降解剂

Nature Communications

IF15.7

2025-11-250

OAAI

Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

NATURE COMMUNICATIONS

IF15.7

2024-10-251

OAAI

A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation

TRIM21-based bioPROTAC突出了HuR降解的治疗益处

NATURE COMMUNICATIONS

IF15.7

2023-11-047

OAAI

Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates

NATURE COMMUNICATIONS

IF15.7

2023-04-1512

OAAI

TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing

IF3.5

2022-07-2310

OAAI

A functional assay for serum detection of antibodies against SARS-CoV-2 nucleoprotein

用于血清检测抗SARS-CoV-2核蛋白抗体的功能测定

IF8.3

2021-07-2917

OA

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

JOURNAL OF CELL BIOLOGY

IF6.4

2021-04-3012

OAAI

Target-induced clustering activates Trim-Away of pathogens and proteins

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-02-2548

OAAI

RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination

NATURE COMMUNICATIONS

IF15.7

2021-02-2230

OAAI

Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

IF8.3

2019-08-2933

OAAI

Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis

IF26.3

2019-04-01149

OAAI

Acute and rapid degradation of endogenous proteins by Trim-Away (vol 13, pg 2149, 2018)

NATURE PROTOCOLS

IF16

2018-11-303

OAAI

Acute and rapid degradation of endogenous proteins by Trim-Away

NATURE PROTOCOLS

IF16

2018-09-24108

OAAI

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

NATURE COMMUNICATIONS

IF15.7

2018-04-27118

OAAI

Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-01-03134

OAAI

A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes

NATURE COMMUNICATIONS

IF15.7

2015-07-06145

OAAI

Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

IF0

2014-02-0474

OA

Restarting life: fertilization and the transition from meiosis to mitosis

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2013-08-14236

OA