Ryan B. Corcoran - Publications, H-index & Citations

Ryan B. Corcoran

Harvard University

63H指数

727论文数

2.2W被引数

收录论文 112

发表时间

Emerging landscape of KRAS inhibitors in cancer treatment 癌症治疗中KRAS抑制剂的新兴景观

Cancer Cell

IF44.5

2026-01-29

OAAI

Jakob M. Riedl; Hiroyuki Matsubara; Reid McNeil; Parasvi S. Patel; Ferran Fece de la Cruz; Doga C. Gulhan; Ryan B. Corcoran

Mechanisms of Clinical Resistance to Selective FGFR2 Inhibition by Lirafugratinib Lirafugratinib对选择性FGFR2抑制的临床耐药机制

Annals of Oncology

IF65.4

2026-01-20

PREAI

H. Ellis; E.R. Balasooriya; A. Varkaris; B. Hajian; J. Wan; M. Shekhar; I. Gritti; V. Vijay; L. Albertelli; S. Piot; K. Lau; A. Kehlmann; N. Chevalier; F.W. Nugent; Y. Zhen; V.S. Silveira; W.R. Sellers; R.B. Corcoran; D. Juric; N. Bardeesy

Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAFV600E metastatic colorectal cancer Ⅰ/Ⅱ期临床试验：encorafenib、cetuximab和nivolumab在微卫星稳定型BRAFV600E转移性结直肠癌中的应用

Cancer Cell

IF44.5

2025-08-28

OAAI

Van K. Morris; Christine M. Parseghian; Vahid Bahrambeigi; Nourhan Abdelfattah; Lianchun Xiao; Anjali Agrawal; Kangyu Lin; Kanwal P.S. Raghav; Robert A. Wolff; Arvind Dasari; Ryan W. Huey; Bryan K. Kee; Michael J. Overman; Jason A. Willis; Phat H. Le; Michelle Escano; Yunyu C. Baig; Kelsey Pan; David Menter; Alda L. Tam; Wai C. Foo; Li Shen; Hey Min Lee; Thomas D. Gallup; Cori Margain; Dave Gallup; Kimal I. Rajapakshe; Paola A. Guerrero; Jing Wang; Ryan B. Corcoran; Anirban Maitra; Kyuson Yun; Scott Kopetz

Mechanisms of genomic resistance across emerging classes of KRAS inhibitors 跨新兴类别的KRAS抑制剂的基因组耐药机制

Annals of Oncology

IF65.4

2025-07-30

PREAI

J.M. Riedl; R.B. Corcoran

The differential immunological impact of photon vs proton radiation therapy in high-grade lymphopenia in patients with gastrointestinal tumors

CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IF3.8

2025-01-01

PREAI

Heather, James M.; Kim, Daniel W.; Sepulveda, Sean M.; van Seventer, Emily E.; Fish, Madeleine G.; Corcoran, Ryan; Hong, Theodore S.; Cobbold, Mark

Overcoming Cell Subtype-Specific Adaptive Resistance to KRAS G12D Inhibition in KRAS G12D-Mutant Pancreatic Cancer

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Lin, Qingxiang (Nick); Morales, Alvin; Barnes, Haley; Corcoran, Ryan Bruce

Frequency of clinical acquired RAS-MAPK pathway resistance alterations in patients treated with KRASG12C inhibitors: An individual patient meta-analysis 接受KRASG12C抑制剂治疗的患者中，临床获得性RAS-MAPK通路耐药性改变的发生频率：一项个体患者荟萃分析

ANNALS OF ONCOLOGY

IF65.4

2024-09-01

PREAI

Riedl, J. M.; Fece, F.; Caughey, B.; Matsubara, H.; Patel, P.; Varkaris, A.; Barnes, H.; Ehnstrom, S.; Schwartz, J.; Lin, J. J.; Parikh, A.; Gainor, J.; Hata, A.; Heist, R.; Corcoran, R. B.

Landscape of acquired resistance mechanisms in gastrointestinal cancers

ANNALS OF ONCOLOGY

IF65.4

2024-06-01

PREAI

Pathak, P. S.; Barnes, H.; Hansen, A.; Caughey, B.; Klempner, S. J.; Parikh, A.; Corcoran, R. B.

Allosteric PI3K-alpha inhibition overcomes on-target resistance to orthosteric inhibitors mediated by secondary PIK3CA mutations

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth; Nordern, Bryanna; Chevalier, Nicholas; Leshchiner, Ignaty; Stavridi, Anastasia; Kim, Janice; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg; Bardia, Aditya; Spring, Laura; Isakoff, Steven; Lennerz, Jochen; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan; Juric, Dejan

Detection of SPEN mutations in advanced breast cancer by circulating tumor cell-free DNA

CANCER RESEARCH

IF16.6

2024-05-02

PREAI

Dai, Charles; Barnes, Haley; Medford, Arielle; Putur, Annika; Keenan, Jennifer; Moy, Beverly; Wander, Seth; Corcoran, Ryan; Bardia, Aditya

Moving towards tissue-agnostic antibody drug conjugates: HER2 expression as the poster child (vol 34, pg 968, 2023)

ANNALS OF ONCOLOGY

IF65.4

2024-05-01

OAAI

Abelman, R.; Spring, L. M.; Corcoran, R. B.; Bardia, A.

KRASG12C inhibition enhances immunogenicity in KRASG12C-mutant colorectal cancer

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Patel, Parasvi S.; Tian, Jun; de la Cruz, Ferran Fece; Curtis, Jacquelyn; Panda, Apekshya; Oka, Tomonori; Demehri, Shadmehr; Sade-Feldman, Moshe; Koptez, Scott; Corcoran, Ryan B.

Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

de la Cruz, Ferran Fece; Varkaris, Andreas; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Patel, Parasvi; Kim, Janice S.; Ellis, Haley; Sanidas, Ioannis; Lau, Kayao T.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan

TOP1 mutations mediate cross resistance to ADCs in metastatic breast cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Abelman, Rachel Occhiogrosso; Barnes, Haley; Medford, Arielle J.; Putur, Annika; Wu, Bogang; Weipert, Caroline; Fell, Geoffrey; Spring, Laura M.; Wander, Seth A.; Moy, Beverly; Varkaris, Andreas; Juric, Dejan; Ellisen, Leif; Corcoran, Ryan; Bardia, Aditya

scRNAseq and TCR repertoire analysis identifies immune correlates of response to combined BRAF/MEK/PD1 inhibition in a phase 2 trial

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Yao, Hongcheng; Jorgji, Vjola; Tang, Alexander L.; Lieb, David; Chao, Sherry X.; Stein, Daniel J.; Spurrell, Maxwell; Elmelech, Liad; Tian, Jun; Sade-Feldman, Moshe; Pelka, Karin; Corcoran, Ryan B.; Hacohen, Nir; Korsunsky, Ilya; Chen, Jonathan

YAP-TAZ-TEAD transcriptional program is a prominent driver of acquired resistance to KRASG12C-based therapies in patients with metastatic colorectal cancer

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Coker, Oluwadara; Sorokin, Alexey; Akhave, Neal; Pan, Kelsey; Gao, Fengqin; Liu, Zhensheng; Kanikarla, Preeti; Lee, HeyMin; Villarreal, Oscar; Alshenaifi, Jumanah; Maddalena, Giulia; Mohamed, Alaa; Prescod, Dionne; Menter, David; Chowdury, Saikat; Corcoran, Ryan; Rai, Kunal; Hong, David; Kopetz, Scott

Sotorasib Is a Pan-RASG12C Inhibitor Capable of Driving Clinical Response in NRASG12C Cancers

CANCER DISCOVERY

IF33.3

2024-01-18

OAAI

Rubinson, Douglas A.; Tanaka, Noritaka; de la Cruz, Ferran Fece; Kapner, Kevin S.; Rosenthal, Michael H.; Norden, Bryanna L.; Barnes, Haley; Ehnstrom, Sara; Morales-Giron, Alvin A.; Brais, Lauren K.; Lemke, Christopher T.; Aguirre, Andrew J.; Corcoran, Ryan B.

Moving towards tissue-agnostic antibody drug conjugates: HER2 expression as the poster child

ANNALS OF ONCOLOGY

IF65.4

2023-11-01

OAAI

Abelman, R.; Spring, L. M.; Corcoran, R.; Bardia, A.

Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations 变构PI3Kα 抑制克服了继发性PIK3CA突变介导的对正构抑制剂的靶向抗性

CANCER DISCOVERY

IF33.3

2023-10-31

OAAI

Varkaris, Andreas; de la Cruz, Ferran Fece; Martin, Elizabeth E.; Norden, Bryanna L.; Chevalier, Nicholas; Kehlmann, Allison M.; Leshchiner, Ignaty; Barnes, Haley; Ehnstrom, Sara; Stavridi, Anastasia-Maria; Yuan, Xin; Kim, Janice S.; Ellis, Haley; Papatheodoridi, Alkistis; Gunaydin, Hakan; Danysh, Brian P.; Parida, Laxmi; Sanidas, Ioannis; Ji, Yongli; Lau, Kayao; Wulf, Gerburg M.; Bardia, Aditya; Spring, Laura M.; Isakoff, Steven J.; Lennerz, Jochen K.; Del Vecchio, Kathryn; Pierce, Levi; Pazolli, Ermira; Getz, Gad; Corcoran, Ryan B.; Juric, Dejan

Final results of a phase I/II study of combined BCL-xL and MEK inhibition with navitoclax and trametinib in KRAS or NRAS mutant advanced solid tumors

ANNALS OF ONCOLOGY

IF65.4

2023-10-01

OAAI

Corcoran, R. B.; Do, K. T.; Cleary, J.; Parikh, A.; Yeku, O.; Weekes, C. D.; Ahronian, L.; Mauri, G.; Tian, J.; Brugge, J.; Juric, D.; Flaherty, K. T.; Sullivan, R. J.; Clark, J.; Heist, R.; Matulonis, U. A.; Liu, J. F.; Shapiro, G. I.

研究方向