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收藏分享 收藏 分享 收藏 RESULTS OF PHASE II STUDY OF NIVOLUMAB FOR PATIENTS WITH MENINGIOMAS REFRACTORY TO SURGERY AND RADIOTHERAPY BASED ON IMMUNE-RELATED RESPONSE CRITERIA WITH MOLECULAR ANALYSES基于免疫相关反应标准及分子分析的尼鲁单抗治疗对手术和放疗无效的脑膜瘤患者的II期研究结果
Sasaki, Hikaru; Takimoto, Tetsuya; Takemura, Ryo; Nakamura, Kohei; Kawano, Ryutaro; Yamaguchi, Shigeru; Adachi, Kazuhide; Kanamori, Masayuki; Kuga, Daisuke; Kamamoto, Dai; Nakaya, Masato; Hino, Utaro; Fujiwara, Hirokazu; Miwa, Tomoru; Nishihara, Hiroshi; Saya, Hideyuki; Kawakami, Yutaka 分享 收藏 Drug Repurposing Screen Identifies Pimozide as a ROS-Inducing Therapy With Anti-Tumor Efficacy in HNSCC PDX Models药物重定位筛选确定了Pimozide是一种在HNSCC PDX模型中具有抗肿瘤效果的ROS诱导疗法Okazaki, Shogo; Nakamura, Shintaro; Soma, Tomoya; Yoshikawa, Momoko; Asoda, Seiji; Nakajima, Yurika; Tsuchihashi, Kenji; Ohmura, Mitsuyo; Goitsuka, Ryo; Imai, Kenichi; Saya, Hideyuki; Nagano, Osamu; Ozawa, Hiroyuki 分享 收藏 Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus肌动蛋白网状结构的形成以及α-平滑肌肌动蛋白在成纤维细胞中的动态变化，对小鼠胎儿的真皮再生具有贡献。Takaya, Kento; Wang, Qi; Imbe, Yuka; Nobusue, Hiroyuki; Okabe, Keisuke; Sakai, Shigeki; Aramaki-Hattori, Noriko; Hanaoka, Kenjiro; Saya, Hideyuki; Kishi, Kazuo 分享 收藏 Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3ζ with H3S28ph苯甲醛通过靶向14-3-3ζ与H3S28ph的相互作用，抑制上皮-间质可塑性并克服癌症的治疗抵抗。Saito, Jun; Onishi, Nobuyuki; Yamasaki, Juntaro; Koike, Naoyoshi; Hata, Yukie; Kimura, Kiyomi; Otsuki, Yuji; Nobusue, Hiroyuki; Sampetrean, Oltea; Shimizu, Takatsune; Okazaki, Shogo; Sugihara, Eiji; Saya, Hideyuki 分享 收藏 Significance of homologous recombinant deficiency as a biomarker for drug sensitivity in colorectal cancerKato, Yujin; Seishima, Ryo; Hattori, Kaoru; Kato, Hirochika; Ishida, Hiroki; Shigeta, Kohei; Okabayashi, Koji; Sugihara, Eiji; Takimoto, Tetsuya; Nakamura, Kohei; Nishihara, Hiroshi; Saya, Hideyuki; Kitagawa, Yuko 分享 收藏 Comprehensive Search for Genes Involved in Thalidomide Teratogenicity Using Early Differentiation Models of Human Induced Pluripotent Stem Cells: Potential Applications in Reproductive and Developmental Toxicity TestingKato, Yu; Inaba, Takeshi; Shinke, Koudai; Hiramatsu, Noriko; Horie, Tetsuhiro; Sakamoto, Takuya; Hata, Yuko; Sugihara, Eiji; Takimoto, Tetsuya; Nagai, Noriaki; Ishigaki, Yasuhito; Kojima, Hajime; Nagano, Osamu; Yamamoto, Naoki; Saya, Hideyuki 分享 收藏 Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgeryOhtsuka, Yoshihiro; Suehiro, Satoshi; Inoue, Akihiro; Ohnishi, Takanori; Nishikawa, Masahiro; Yamashita, Daisuke; Yano, Hajime; Choudhury, Mohammed E.; Ozaki, Saya; Sampetrean, Oltea; Saya, Hideyuki; Watanabe, Hideaki; Tanaka, Junya; Kunieda, Takeharu 分享 收藏 Anticancer properties and metabolomic profiling of Shorea roxburghii extracts toward gastrointestinal cancer cell linesJanthamala, Sutthiwan; Promraksa, Bundit; Thanee, Malinee; Duenngai, Kunyarat; Jusakul, Apinya; Kongpetch, Sarinya; Kraiklang, Ratthaphol; Thanee, Kidsada; Pinlaor, Porntip; Namwat, Nisana; Saya, Hideyuki; Techasen, Anchalee 分享 收藏 ASO Author Reflections: Vasohibin-1 as a Biomarker for Chemotherapeutic Response in Patients with Advanced Bladder CancerOmura, Minami; Kosaka, Takeo; Kobayashi, Hiroaki; Shigeta, Keisuke; Matsumoto, Kazuhiro; Hara, Satoshi; Kikuchi, Eiji; Mikami, Shuji; Saya, Hideyuki; Sato, Yasufumi; Oya, Mototsugu 分享 收藏 Integration of human omics analysis and new syngeneic tumor organoid models reveals that aberrant RAS/PI3K crosstalk triggers refractoriness in high-grade serous carcinomaTamura, Tomohiro; Masuda, Kenta; Nagai, Shimpei; Imaeda, Keiyo; Yamasaki, Juntaro; Sugihara, Eiji; Nobusue, Hiroyuki; Otsuki, Yuji; Yamaguchi, Rui; Sakurada, Kazuhiro; Yamagami, Wataru; Saya, Hideyuki; Nagano, Osamu 分享 收藏 Vasohibin-1 Expression Can Predict Pathological Complete Remission of Advanced Bladder Cancer with Neoadjuvant ChemotherapyOmura, Minami; Kosaka, Takeo; Kobayashi, Hiroaki; Shigeta, Keisuke; Matsumoto, Kazuhiro; Hara, Satoshi; Kikuchi, Eiji; Mikami, Shuji; Saya, Hideyuki; Sato, Yasufumi; Oya, Mototsugu 分享 收藏 Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironmentYonemura, Atsuko; Semba, Takashi; Zhang, Jun; Fan, Yibo; Yasuda-Yoshihara, Noriko; Wang, Huaitao; Uchihara, Tomoyuki; Yasuda, Tadahito; Nishimura, Akiho; Fu, Lingfeng; Hu, Xichen; Wei, Feng; Kitamura, Fumimasa; Akiyama, Takahiko; Yamashita, Kohei; Eto, Kojiro; Iwagami, Shiro; Iwatsuki, Masaaki; Miyamoto, Yuji; Matsusaki, Keisuke; Yamasaki, Juntaro; Nagano, Osamu; Saya, Hideyuki; Song, Shumei; Tan, Patrick; Baba, Hideo; Ajani, Jaffer A.; Ishimoto, Takatsugu 分享 收藏 Role of androgen signaling in androgen receptor-positive extramammary Paget's disease: Establishment of organoids and their biological analysis as a novel therapeutic targetNakamura, Yoshio; Mizukami, Hayase; Tanese, Keiji; Fusumae, Takayuki; Hirai, Ikuko; Amagai, Masayuki; Takamatsu, Reika; Nakamura, Kohei; Nishihara, Hiroshi; Takimoto, Tetsuya; Ueno, Masaru; Saya, Hideyuki; Funakoshi, Takeru 分享 收藏 Growth Transformation of B Cells by Epstein-Barr Virus Requires IMPDH2 Induction and Nucleolar Hypertrophy爱泼斯坦-巴尔病毒对b细胞的生长转化需要IMPDH2诱导和核仁肥大Sugimoto, Atsuko; Watanabe, Takahiro; Matsuoka, Kazuhiro; Okuno, Yusuke; Yanagi, Yusuke; Narita, Yohei; Mabuchi, Seiyo; Nobusue, Hiroyuki; Sugihara, Eiji; Hirayama, Masaya; Ide, Tomihiko; Onouchi, Takanori; Sato, Yoshitaka; Kanda, Teru; Saya, Hideyuki; Iwatani, Yasumasa; Kimura, Hiroshi; Murata, Takayuki 分享 收藏 5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapyFukumura, Masao; Nonoguchi, Naosuke; Kawabata, Shinji; Hiramatsu, Ryo; Futamura, Gen; Takeuchi, Koji; Kanemitsu, Takuya; Takata, Takushi; Tanaka, Hiroki; Suzuki, Minoru; Sampetrean, Oltea; Ikeda, Naokado; Kuroiwa, Toshihiko; Saya, Hideyuki; Nakano, Ichiro; Wanibuchi, Masahiko 分享 收藏 Comprehensive analysis of copy number variation and sensitivity to targeted therapy in renal cell carcinoma using in-house cancer gene panel testingTakeuchi, Akhito; Takeda, Mayu; Sugihara, Eiji; Muto, Yoshinari; Nohara, Sachio; Tanishima, Shigeki; Zennami, Kenji; Takahara, Kiyoshi; Tsukamoto, Tetsuya; Shiroki, Ryoichi; Saya, Hideyuki; Sumitomo, Makoto 分享 收藏 分享 收藏 
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