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T

Takatsugu Ishimoto

Japanese Foundation for Cancer Research
H指数:64
被引数:1.4万

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荣誉奖项

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Frizzled-1 amplification promotes fibrosis in the gastric tumor microenvironment through the activation of fibroblasts via the SLIT2/ROBO1 axis

Frizzled-1扩增通过SLIT2/ROBO1轴的激活促进胃癌微环境中成纤维细胞介导的纤维化。

Gastric Cancer
IF5.1
2026-01-040
PRE
Yilin Tong; Takashi Semba; Akiho Nishimura; Atsuko Yonemura; Masaya Yamazaki; Huaitao Wang; Lingfeng Fu; Yuya Okamoto; Takahiro Shoda; Takuya Tajiri; Masami Yamamoto; Tetsuya Tsukamoto; Sachiyo Nomura; Masaaki Iwatsuki; Takatsugu Ishimoto
Serum Mac2-binding protein glycosylated isomer (M2BPGi) as a prognostic biomarker in pancreatic ductal adenocarcinoma: iCAFs-derived M2BPGi drives tumor invasion

血清Mac2-binding蛋白糖基化异构体 (M2BPGi) 作为胰腺导管腺癌的预后生物标志物: iCAFs衍生的M2BPGi驱动肿瘤侵袭

JOURNAL OF GASTROENTEROLOGY
IF5.5
2024-12-110
PRE
Kugiyama, Naotaka; Nagaoka, Katsuya; Yamada, Rin; Watanabe, Takehisa; Yamazaki, Hajime; Ushijima, Shinya; Otsuka, Fumiya; Uramoto, Yukiko; Iwasaki, Hajime; Yoshinari, Motohiro; Hashigo, Shunpei; Hayashi, Hiromitsu; Ishimoto, Takatsugu; Komohara, Yoshihiro; Tanaka, Yasuhito
Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment
CELL REPORTS
IF6.9
2024-01-017
OA
Yonemura, Atsuko; Semba, Takashi; Zhang, Jun; Fan, Yibo; Yasuda-Yoshihara, Noriko; Wang, Huaitao; Uchihara, Tomoyuki; Yasuda, Tadahito; Nishimura, Akiho; Fu, Lingfeng; Hu, Xichen; Wei, Feng; Kitamura, Fumimasa; Akiyama, Takahiko; Yamashita, Kohei; Eto, Kojiro; Iwagami, Shiro; Iwatsuki, Masaaki; Miyamoto, Yuji; Matsusaki, Keisuke; Yamasaki, Juntaro; Nagano, Osamu; Saya, Hideyuki; Song, Shumei; Tan, Patrick; Baba, Hideo; Ajani, Jaffer A.; Ishimoto, Takatsugu
Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion

15-PGDH的下调通过脂肪酸诱导的T细胞耗竭增强MASH-HCC的发展

JHEP REPORTS
IF7.5
2023-12-012
OAAI
Hu, Xichen; Yasuda, Tadahito; Yasuda-Yosihara, Noriko; Yonemura, Atsuko; Umemoto, Terumasa; Nakachi, Yutaka; Yamashita, Kohei; Semba, Takashi; Arima, Kota; Uchihara, Tomoyuki; Nishimura, Akiho; Bu, Luke; Fu, Lingfeng; Wei, Feng; Zhang, Jun; Tong, Yilin; Wang, Huaitao; Iwamoto, Kazuya; Fukuda, Takaichi; Nakagawa, Hayato; Taniguchi, Koji; Miyamoto, Yuji; Baba, Hideo; Ishimoto, Takatsugu
Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer
JCI INSIGHT
IF6.1
2023-10-2320
OAAI
Kitamura, Fumimasa; Semba, Takashi; Yasuda-Yoshihara, Noriko; Yamada, Kosuke; Nishimura, Akiho; Yamasaki, Juntaro; Nagano, Osamu; Yasuda, Tadahito; Yonemura, Atsuko; Tong, Yilin; Wang, Huaitao; Akiyama, Takahiko; Matsumura, Kazuki; Uemura, Norio; Itoyama, Rumi; Bu, Luke; Fu, Lingfeng; Hu, Xichen; Wei, Feng; Mima, Kosuke; Imai, Katsunori; Hayashi, Hiromitsu; Yamashita, Yo-ichi; Miyamoto, Yuji; Baba, Hideo; Ishimoto, Takatsugu
Cellular senescence induction leads to progressive cell death via the INK4a-RB pathway in naked mole-rats

裸mole鼠的细胞衰老诱导通过INK4a-RB途径导致进行性细胞死亡

EMBO JOURNAL
IF8.3
2023-07-1110
OA
Kawamura, Yoshimi; Oka, Kaori; Semba, Takashi; Takamori, Mayuko; Sugiura, Yuki; Yamasaki, Riyo; Suzuki, Yusuke; Chujo, Takeshi; Nagase, Mari; Oiwa, Yuki; Fujioka, Shusuke; Homma, Sayuri; Yamamura, Yuki; Miyawaki, Shingo; Narita, Minoru; Fukuda, Takaichi; Sakai, Yusuke; Ishimoto, Takatsugu; Tomizawa, Kazuhito; Suematsu, Makoto; Yamamoto, Takuya; Bono, Hidemasa; Okano, Hideyuki; Miura, Kyoko
Stromal Reprogramming through Dual PDGFRa/b Blockade Boosts the Efficacy of Anti-PD-1 in Fibrotic Tumors
CANCER RESEARCH
IF16.6
2022-12-2134
OA
Akiyama, Takahiko; Yasuda, Tadahito; Uchihara, Tomoyuki; Yasuda-Yoshihara, Noriko; Tan, Benjy J. Y.; Yonemura, Atsuko; Semba, Takashi; Yamasaki, Juntaro; Komohara, Yoshihiro; Ohnishi, Koji; Wei, Feng; Fu, Lingfeng; Zhang, Jun; Kitamura, Fumimasa; Yamashita, Kohei; Eto, Kojiro; Iwagami, Shiro; Tsukamoto, Hirotake; Umemoto, Terumasa; Masuda, Mari; Nagano, Osamu; Satou, Yorifumi; Saya, Hideyuki; Tan, Patrick; Baba, Hideo; Ishimoto, Takatsugu
IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment
GASTRIC CANCER
IF5.1
2022-12-1319
OA
Zhang, Jun; Fu, Lingfeng; Yasuda-Yoshihara, Noriko; Yonemura, Atsuko; Wei, Feng; Bu, Luke; Hu, Xichen; Akiyama, Takahiko; Kitamura, Fumimasa; Yasuda, Tadahito; Semba, Takashi; Uchihara, Tomoyuki; Itoyama, Rumi; Yamashita, Kohei; Eto, Kojiro; Iwagami, Shiro; Yashiro, Masakazu; Komohara, Yoshihiro; Baba, Hideo; Ishimoto, Takatsugu

研究方向

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H
Hideo Baba
H 指数:87论文数:1,255被引数:3.4万
Y
Yoshifumi Baba
H 指数:72论文数:513被引数:1.9万
N
Naoya Yoshida
H 指数:64论文数:630被引数:1.6万
M
Masaaki Iwatsuki
H 指数:60论文数:635被引数:1.3万
Y
Yuji Miyamoto
H 指数:57论文数:772被引数:1.2万
M
Masayuki Watanabe
H 指数:66论文数:552被引数:1.6万
S
Shiro Iwagami
H 指数:40论文数:302被引数:5,808
K
Kojiro Eto
H 指数:23论文数:214被引数:2,133
K
Kazuto Harada
H 指数:37论文数:237被引数:4,562
K
Keisuke Miyake
H 指数:37论文数:165被引数:4,614