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Patrick Seale

University of Pennsylvania

65H指数
173论文数
2.9W被引数
收录论文 69
发表时间
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Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling线粒体载体SLC25A34连接时钟、饮食和温度对脂肪细胞脂质循环的控制
errScience
IF45.8
err2026-10-01
err0
PREAI
errIuliia Karavaeva; Astrid Linde Basse; Samuel A. J. Trammell; Mohammed Faiz Hussain; Lasse Kruse Markussen; Jesper F. Havelund; Marie Sophie Isidor; Adam Chatoff; Andrea Andress Huacachino; Hannah J. Richter; Meghna Birla; Sabina Chubanava; Yann Deleye; Rini Arianti; David Tandio; Sarah E. Utzon; Zafir Kaiser; Yachen Shen; Ditte Neess; Hannes Embring; Dilip Menon; Olivia J. Conway; Frederike Sass; Fabian Finger; Lidia Argemi-Muntadas; Tao Ma; Elahu G. Sustarsic; Cecilie Kynding Kristensen; Rebecca L. McIntyre; Genesee J. Martinez; Anna Sofie Husted; Matthew J. Emmett; Zachary A. Kipp; Mikkel Frost; Mark P. Jedrychowski; Michel van Weeghel; Homa Majd; Ekaterina Zhuravleva; Robert W. McGarrah; Kaja Plucińska; Mohit K. Midha; Andreas Prokesch; Paul Cohen; James G. Granneman; Patrick Seale; Riekelt H. Houtkooper; Jacob B. Hansen; Steven P. Gygi; Thue W. Schwartz; Matthew P. Gillum; Terry D. Hinds; Raymond E. Soccio; Phillip J. White; Edmund R. S. Kunji; Thomas Moritz; Jonas T. Treebak; Endre Kristóf; Susanne Mandrup; Brice Emanuelli; Nathaniel W. Snyder; Daniel J. Fazakerley; Lawrence Kazak; Nils J. Færgeman; Mitchell A. Lazar; Zachary Gerhart-Hines
err分享
err收藏
TRF2 couples muscle stem cell identity to regenerative repairTRF2将肌肉干细胞特性与再生修复相偶联
errScience Advances
IF12.5
err2026-07-31
err0
errOAAI
errJi-Hyung Lee; Kiran Kumar Nakka; Ryan P. Calhoun; Sarah Hachmer; Adity Gupta; Eric Arreza; Lynn A. Megeney; Patrick Seale; Roger A. Greenberg; F. Jeffrey Dilworth; Foteini Mourkioti
err分享
err收藏
ILC2s regulate a fibroblast progenitor niche in the pancreasILC2s调节胰腺中的成纤维细胞祖细胞微环境
errScience
IF45.8
err2026-07-02
err0
PREAI
errThomas Yip; Julie Stockis; Charlotte Simpson; Erika E. McCartney; Shwetha Raghunathan; Martha M. Rangel-Sosa; Sydney N. Hummel; Julia Moreno-Vicente; Gianmarco Raddi; Celine Garcia; Rugile Linkute; Silvain Pinaud; Maye F. Cheng; Lesley A. Hill; T. Michael Underhill; Hans-Reimer Rodewald; Christoph Schneider; Claus Jørgensen; Andrew N.J. McKenzie; Sophie E. Acton; Patrick Seale; Menna R. Clatworthy; Matthew B. Buechler; Timotheus Y. F. Halim
err分享
err收藏
Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant葡萄糖激酶活性抑制肝胆固醇合成和甘油三酯积累：GKRP P466L常见人类变异效应的新模型
errMolecular Metabolism
IF6.6
err2026-06-18
err0
errOAAI
errDominic Santoleri; Sarah Traynor; Ryan Calhoun; Matthew J. Gavin; David Merrick; Patrick Seale; Paul M. Titchenell
err分享
err收藏
The Innate Thermogenic Capacity of Brown Adipose Tissue Develops Independently of Sympathetic Signaling棕色脂肪组织的固有产热能力独立于交感神经信号而发展
errMolecular Metabolism
IF6.6
err2025-12-09
err0
errOAAI
errEthan C. Fein; Sarmistha Mukherjee; Joseph A. Baur; Patrick Seale
err分享
err收藏
3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility基于3D染色质的变异-基因图谱在57种人类细胞类型中的研究揭示了自身免疫性疾病易感性的细胞和遗传架构
errGenome Biology
IF9.4
err2025-12-08
err0
errOAAI
errKhanh B. Trang; Prabhat Sharma; Laura Cook; Zachary Mount; Rajan M. Thomas; Nikhil N. Kulkarni; Emylette Cruz Cabrera; Suzanna Rachimi; Matthew C. Pahl; James A. Pippin; Chun Su; Klaus H. Kaestner; Joan M. O’Brien; Yadav Wagley; Kurt D. Hankenson; Ashley Jermusyk; Jason W. Hoskins; Laufey T. Amundadottir; Mai Xu; Kevin M. Brown; Stewart A. Anderson; Wenli Yang; Paul M. Titchenell; Patrick Seale; Babette S. Zemel; Alessandra Chesi; Neil Romberg; Megan K. Levings; Struan F. A. Grant; Andrew D. Wells
err分享
err收藏
The Transcription Factor CUX1 Exerts Opposing Roles in Human and Mouse Adipocyte Differentiation转录因子CUX1在人类和小鼠脂肪细胞分化中发挥相反的作用
errMolecular Metabolism
IF6.6
err2025-11-27
err0
errOAAI
errYang Chen; Lin Liu; Ryan Calhoun; Lan Cheng; David Steger; Patrick Seale
err分享
err收藏
PRDM16 regulates smooth muscle cell identity and atherosclerotic plaque compositionPRDM16调控平滑肌细胞特性及动脉粥样硬化斑块组成
errNature Cardiovascular Research
IF10.8
err2025-10-17
err0
errOAAI
errJosephine M. E. Tan; Lan Cheng; Ryan P. Calhoun; Angela H. Weller; Karima Drareni; Skylar Fong; Eirlys Barbara; Hee-Woong Lim; Chenyi Xue; Hanna Winter; Gaëlle Auguste; Clint L. Miller; Muredach P. Reilly; Lars Maegdefessel; Esther Lutgens; Patrick Seale
err分享
err收藏
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
errELIFE
IF0
err2025-01-15
err0
errOAAI
errTrang, Khanh B.; Pahl, Matthew C.; Pippin, James A.; Su, Chun; Littleton, Sheridan H.; Sharma, Prabhat; Kulkarni, Nikhil N.; Ghanem, Louis R.; Terry, Natalie A.; O'Brien, Joan M.; Wagley, Yadav; Hankenson, Kurt D.; Jermusyk, Ashley; Hoskins, Jason; Amundadottir, Laufey T.; Xu, Mai; Brown, Kevin; Anderson, Stewart; Yang, Wenli; Titchenell, Paul; Seale, Patrick; Kaestner, Klaus H.; Cook, Laura; Levings, Megan; Zemel, Babette S.; Chesi, Alessandra; Wells, Andrew D.; Grant, Struan F. A.
err分享
err收藏
The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis
errNPJ AGING
IF6
err2024-07-15
err8
errOAAI
errWang, Magnolia G.; Seale, Patrick; Furman, David
err分享
err收藏
Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming
errELIFE
IF0
err2024-05-22
err6
errOAAI
errHolman, Corey D.; Sakers, Alexander P.; Calhoun, Ryan P.; Cheng, Lan; Fein, Ethan C.; Jacobs, Christopher; Tsai, Linus; Rosen, Evan D.; Seale, Patrick
err分享
err收藏
Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism
errMOLECULAR METABOLISM
IF6.6
err2024-02-01
err19
errOAAI
errNunn, Elizabeth; Jaiswal, Natasha; Gavin, Matthew; Uehara, Kahealani; Stefkovich, Megan; Drareni, Karima; Calhoun, Ryan; Lee, Michelle; Holman, Corey D.; Baur, Joseph A.; Seale, Patrick; Titchenell, Paul M.
err分享
err收藏
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology人髌下脂肪垫和滑膜的单细胞图谱在骨关节炎病理学中涉及APOE信号传导
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-01-24
err16
PREAI
errTang, Su'an; Yao, Lutian; Ruan, Jianzhao; Kang, Jingliang; Cao, Yumei; Nie, Xiaoyu; Lan, Weiren; Zhu, Zhaohua; Han, Weiyu; Liu, Yongguang; Tian, Jing; Seale, Patrick; Qin, Ling; Ding, Changhai
err分享
err收藏
Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis
errJOURNAL OF BONE AND MINERAL RESEARCH
IF5.9
err2024-01-04
err15
errOAAI
errLi, Jun; Gui, Tao; Yao, Lutian; Guo, Hanli; Lin, Yu-Lieh; Lu, Jiawei; Duffy, Michael; Zgonis, Miltiadis; Mauck, Robert; Dyment, Nathaniel; Zhang, Yejia; Scanzello, Carla; Seale, Patrick; Qin, Ling
err分享
err收藏
IRF2BP2 Regulates Hormone Sensitive Lipase and Lipolysis in Human Adipocytes and in Mice
errCIRCULATION
IF38.6
err2023-11-07
err0
PREAI
errChen, Yang; Liu, Lin; Steger, David; Cheng, Lan; Stewart, Alexandre F.; Seale, Patrick
err分享
err收藏
Control of murine brown adipocyte development by GATA6
errDEVELOPMENTAL CELL
IF8.7
err2023-11-01
err5
PREAI
errJun, Seoyoung; Angueira, Anthony R.; Fein, Ethan C.; Tan, Josephine M. E.; Weller, Angela H.; Cheng, Lan; Batmanov, Kirill; Ishibashi, Jeff; Sakers, Alexander P.; Stine, Rachel R.; Seale, Patrick
err分享
err收藏
A subpopulation of lipogenic brown adipocytes drives thermogenic memory
errNATURE METABOLISM
IF20.8
err2023-10-02
err10
errOAAI
errLundgren, Patrick; Sharma, Prateek V.; Dohnalova, Lenka; Coleman, Kyle; Uhr, Giulia T.; Kircher, Susanna; Litichevskiy, Lev; Bahnsen, Klaas; Descamps, Helene C.; Demetriadou, Christina; Chan, Jacqueline; Chellappa, Karthikeyani; Cox, Timothy O.; Heyman, Yael; Pather, Sarshan R.; Shoffler, Clarissa; Petucci, Christopher; Shalem, Ophir; Raj, Arjun; Baur, Joseph A.; Snyder, Nathaniel W.; Wellen, Kathryn E.; Levy, Maayan; Seale, Patrick; Li, Mingyao; Thaiss, Christoph A.
err分享
err收藏
Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err111
errOAAI
errSabourin, LA; Seale, P; Wagner, J; Rudnicki, MA
err分享
err收藏
The Role of PDE3B Phosphorylation in the Inhibition of Lipolysis by Insulin
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err85
errOAAI
errDiPilato, Lisa M.; Ahmad, Faiyaz; Harms, Matthew; Seale, Patrick; Manganiello, Vincent; Birnbaum, Morris J.
err分享
err收藏
An Evil-C/EBPβ Complex Controls Perwdsome Proliferator-Activated Receptor γ2 Gene Expression To Initiate White Fat Cell Differentiation
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err28
errOAAI
errIshibashi, Jeff; Firtina, Zeynep; Rajakumari, Sona; Wood, Kathleen H.; Conroe, Heather M.; Steger, David J.; Seale, Patrick
err分享
err收藏

研究方向

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M
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