Paul M. Titchenell - Publications, H-index & Citations

Paul M. Titchenell

University of Pennsylvania

26H指数

80论文数

4.1K被引数

收录论文 38

发表时间

Divergent AKT Signalling Mechanisms Regulate GLUT4 Translocation and Glucose Uptake in Skeletal Muscle and Adipose Tissue 不同AKT信号机制调控骨骼肌和脂肪组织中GLUT4转位及葡萄糖摄取

Journal of Cachexia Sarcopenia and Muscle

IF9.1

2026-07-28

OAAI

Natasha Jaiswal; Matthew Gavin; Louise Lantier; Olivia Yu Yu Ong; David H. Wasserman; Paul M. Titchenell

Acute AKT signaling increases glucose phosphorylation and contribution to glycogen in hepatocytes 急性AKT信号通路增强肝细胞的葡萄糖磷酸化及其对糖原的贡献

iScience

IF4.1

2026-07-01

PREAI

Stefkovich, Megan; Lee, Won Dong; Coopersmith, Talia; Baur, Joseph A.; Rabinowitz, Joshua D.; Titchenell, Paul M.

Weight loss with GLP-1 medicines does not result in a disproportionate loss of muscle mass or function in obese mice and humans 使用GLP-1药物减肥不会导致肥胖小鼠和人类肌肉质量或功能的失衡性损失

Cell Reports Medicine

IF10.6

2026-03-17

OAAI

Henning Tim Langer; Natalie K. Gilmore; Christopher M.T. Hayden; Julien Roux; Bruno Bariohay; Thaïs Rouquet; Manar Awada; Julie Marcotorchino; Lorrine Bournot; Elizabeth Nunn; Paul M. Titchenell; Daniela Liskiewicz; Timo D. Müller; Oluwaseun Anyiam; Philip J. Atherton; Iskandar Idris; Andreas Hentschel; Andreas Roos; Natalie Haritonow; Kristina Norman

3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility 基于3D染色质的变异-基因图谱在57种人类细胞类型中的研究揭示了自身免疫性疾病易感性的细胞和遗传架构

Genome Biology

IF9.4

2025-12-08

OAAI

Khanh B. Trang; Prabhat Sharma; Laura Cook; Zachary Mount; Rajan M. Thomas; Nikhil N. Kulkarni; Emylette Cruz Cabrera; Suzanna Rachimi; Matthew C. Pahl; James A. Pippin; Chun Su; Klaus H. Kaestner; Joan M. O’Brien; Yadav Wagley; Kurt D. Hankenson; Ashley Jermusyk; Jason W. Hoskins; Laufey T. Amundadottir; Mai Xu; Kevin M. Brown; Stewart A. Anderson; Wenli Yang; Paul M. Titchenell; Patrick Seale; Babette S. Zemel; Alessandra Chesi; Neil Romberg; Megan K. Levings; Struan F. A. Grant; Andrew D. Wells

A consensus guide to preclinical indirect calorimetry experiments 临床前间接测热法实验的共识指南

Nature Metabolism

IF20.8

2025-09-24

PREAI

Alexander S. Banks; David B. Allison; Thierry Alquier; Ansarullah; Steven N. Austad; Johan Auwerx; Julio E. Ayala; Joseph A. Baur; Stefania Carobbio; Gary A. Churchill; Morten Dall; Rafael de Cabo; Jose Donato; Nathalia R. V. Dragano; Carol F. Elias; Anthony W. Ferrante; Brian N. Finck; Jose E. Galgani; Zachary Gerhart-Hines; Laurie J. Goodyear; Justin L. Grobe; Rana K. Gupta; Kirk M. Habegger; Sean M. Hartig; Andrea L. Hevener; Steven B. Heymsfield; Corey D. Holman; Martin Hrabě de Angelis; David E. James; Lawrence Kazak; Jae Bum Kim; Martin Klingenspor; Xingxing Kong; Sander Kooijman; Louise Lantier; K. C. Kent Lloyd; James C. Lo; Irfan J. Lodhi; Paul S. MacLean; Owen P. McGuinness; Gema Medina-Gómez; Raghavendra G. Mirmira; Christopher D. Morrison; Gregory J. Morton; Timo D. Müller; Yoshihiro Ogawa; David Pajuelo-Reguera; Matthew J. Potthoff; Nathan Qi; Marc L. Reitman; Patrick C. N. Rensen; Jan Rozman; Jennifer M. Rutkowsky; Kei Sakamoto; Philipp E. Scherer; Gary J. Schwartz; Radislav Sedlacek; Mohammed Selloum; Saame Raza Shaikh; Shuai Chen; Gerald I. Shulman; Vojtěch Škop; Alexander A. Soukas; John R. Speakman; Bruce M. Spiegelman; Gregory R. Steinberg; Katrin J. Svensson; John P. Thyfault; Tony Tiganis; Paul M. Titchenell; Nigel Turner; Licio A. Velloso; Antonio Vidal-Puig; Christopher S. Ward; Ashley S. Williams; Christian Wolfrum; Allison W. Xu; Ying Xu; Juleen R. Zierath

Ppp1r3b is a metabolic switch that shifts hepatic energy storage from lipid to glycogen Ppp1r3b是一种代谢开关，可将肝脏能量储存从脂质转向糖原

SCIENCE ADVANCES

IF12.5

2025-05-16

OAAI

Creasy, Kate Townsend; Mehta, Minal B.; Schneider, Carolin V.; Park, Joseph; Zhang, David; Shewale, Swapnil V.; Millar, John S.; Vujkovic, Marijana; Hand, Nicholas J.; Titchenell, Paul M.; Baur, Joseph A.; Rader, Daniel J.

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

ELIFE

IF0

2025-01-15

OAAI

Trang, Khanh B.; Pahl, Matthew C.; Pippin, James A.; Su, Chun; Littleton, Sheridan H.; Sharma, Prabhat; Kulkarni, Nikhil N.; Ghanem, Louis R.; Terry, Natalie A.; O'Brien, Joan M.; Wagley, Yadav; Hankenson, Kurt D.; Jermusyk, Ashley; Hoskins, Jason; Amundadottir, Laufey T.; Xu, Mai; Brown, Kevin; Anderson, Stewart; Yang, Wenli; Titchenell, Paul; Seale, Patrick; Kaestner, Klaus H.; Cook, Laura; Levings, Megan; Zemel, Babette S.; Chesi, Alessandra; Wells, Andrew D.; Grant, Struan F. A.

Lactate homeostasis is maintained through regulation of glycolysis and lipolysis 乳酸稳态通过糖酵解和脂解作用的调节来维持。

CELL METABOLISM

IF30.9

2025-01-01

PREAI

Lee, Won Dong; Weilandt, Daniel R.; Liang, Lingfan; Macarthur, Michael R.; Jaiswal, Natasha; Ong, Olivia; Mann, Charlotte G.; Chu, Qingwei; Hunter, Craig J.; Ryseck, Rolf-Peter; Lu, Wenyun; Oschmann, Anna M.; Cowan, Alexis J.; Teslaa, Tara A.; Bartman, Caroline R.; Jang, Cholsoon; Baur, Joseph A.; Titchenell, Paul M.; Rabinowitz, Joshua D.

Myeloid-derived miR-6236 potentiates adipocyte insulin signaling and prevents hyperglycemia during obesity

NATURE COMMUNICATIONS

IF15.7

2024-06-25

OAAI

Paneru, Bam D.; Chini, Julia; McCright, Sam J.; Demarco, Nicole; Miller, Jessica; Joannas, Leonel D.; Henao-Mejia, Jorge; Titchenell, Paul M.; Merrick, David M.; Lim, Hee-Woong; Lazar, Mitchell A.; Hill, David A.

Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism

MOLECULAR METABOLISM

IF6.6

2024-02-01

OAAI

Nunn, Elizabeth; Jaiswal, Natasha; Gavin, Matthew; Uehara, Kahealani; Stefkovich, Megan; Drareni, Karima; Calhoun, Ryan; Lee, Michelle; Holman, Corey D.; Baur, Joseph A.; Seale, Patrick; Titchenell, Paul M.

mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b mTORC1通过Ppp1r3b控制小鼠餐后肝糖原合成

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2024-01-30

OAAI

Uehara, Kahealani; Lee, Won Dong; Stefkovich, Megan; Biswas, Dipsikha; Santoleri, Dominic; Whitlock, Anna Garcia; Quinn III, William; Coopersmith, Talia; Creasy, Kate Townsend; Rader, Daniel J.; Sakamoto, Kei; Rabinowitz, Joshua D.; Titchenell, Paul M.

Location Matters: Mitochondrial Arginase 2 as a Treatment for Metabolic Disease?

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2024-01-01

OAAI

Stefkovich, Megan; Titchenell, Paul m.

ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-12-05

OAAI

Mukhi, Dhanunjay; Li, Lingzhi; Liu, Hongbo; Doke, Tomohito; Kolligundla, Lakshmi P.; Ha, Eunji; Kloetzer, Konstantin; Abedini, Amin; Mukherjee, Sarmistha; Wu, Junnan; Dhillon, Poonam; Hu, Hailong; Guan, Dongyin; Funai, Katsuhiko; Uehara, Kahealani; Titchenell, Paul M.; Baur, Joseph A.; Wellen, Kathryn E.; Susztak, Katalin

Insulin Regulation of Hepatic Lipid Homeostasis 胰岛素对肝脏脂质稳态的调节

COMPREHENSIVE PHYSIOLOGY

IF5.2

2023-06-26

OAAI

Uehara, Kahealani; Santoleri, Dominic; Whitlock, Anna E. Garcia; Titchenell, Paul M.

ENT-03, a Centrally Acting Endogenous Spermine Bile Acid with PTP1B Inhibitory Activity, Has Potent Effects on Metabolism and Weight in a Mouse Model of Diet-Induced Obesity (DIO)

DIABETES

IF7.5

2023-06-20

PREAI

Barbut, Denise; Baur, Joseph A.; Titchenell, Paul M.; Davis, James G.; Zemel, Michael B.; Fleming, G. Alexander; Moses, Alan C.; Zasloff, Michael

Liver Fat-Gone, but Not Forgotten?

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2023-01-01

OAAI

Titchenell, Paul M.; Baur, Joseph A.

Acute Deletion of the FOXO1-dependent Hepatokine FGF21 Does not Alter Basal Glucose Homeostasis or Lipolysis in Mice

ENDOCRINOLOGY

IF3.3

2022-03-18

OAAI

Sostre-Colon, Jaimarie; Gavin, Matthew J.; Santoleri, Dominic; Titchenell, Paul M.

Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis 肝脏mTORC1的激活通过双重调节VLDL-TAG分泌和从头脂肪生成来预防NASH

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2022-01-01

OAAI

Uehara, Kahealani; Sostre-Colon, Jaimarie; Gavin, Matthew; Santoleri, Dominic; Leonard, Kelly -Ann; Jacobs, Rene L.; Titchenell, Paul M.

Curing Fatty Liver with Oxysterols?

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY

IF7.4

2022-01-01

OAAI

Uehara, K. A. H. E. A. L. A. N., I; Titchenell, Paul M.

AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE

IF9.1

2021-11-09

OAAI

Jaiswal, Natasha; Gavin, Matthew; Loro, Emanuele; Sostre-Colon, Jaimarie; Roberson, Paul A.; Uehara, Kahealani; Rivera-Fuentes, Nicole; Neinast, Michael; Arany, Zoltan; Kimball, Scot R.; Khurana, Tejvir S.; Titchenell, Paul M.

研究方向