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Tomotaka Ugai

Harvard Medical School
H指数:30
被引数:3,869

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Insights into early-onset colorectal cancer from a single-nucleus RNA-seq atlas of colorectal cancer across the age continuum

从跨越年龄连续体的结直肠癌单核RNA测序图谱中获得的关于早发性结直肠癌的见解

Nature Medicine
IF50
2026-10-290
OAAI
Caroline B. M. Porter; Shane P. Murphy; Jules Cazaubiel; Toni M. Delorey; Liat Amir-Zilberstein; Orr Ashenberg; Liubou Klindziuk; Elizabeth Andrews; William Tan; Kosuke Matsuda; Atsushi Kondo; Satoko Ugai; Tomotaka Ugai; Shuji Ogino; Emily Finan; Jacques Deguine; Ewa Sicinska; Lauren K. Brais; Jennifer S. Thalappillil; Marios Giannakis; Ramnik J. Xavier; Ana C. Anderson; Kimmie Ng
RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation

RNF43 p.G659fs通过PI3K/AKT/mTOR信号通路和HLA-E上调导致MSI-high结直肠癌中自然杀伤细胞功能障碍

Science Advances
IF12.5
2026-09-230
OA
Pushpamali De Silva; Samantha Fitzgerald; Jules Cazaubiel; Kristin Qian; Matan Hofree; Jia-Ren Lin; Roxanne Pelletier; Mariana Lopez Leon; Phuong Vu Mai Ho; Yasutoshi Takashima; Juha P Väyrynen; Kosuke Matsuda; Tomotaka Ugai; Dane Ford-Roshon; Pratyusha Bala; Nir Hacohen; Kimmie Ng; Jonathan A. Nowak; Shuji Ogino; Peter K. Sorger; Marios Giannakis
Cigarette smoking and long-term incidence of colorectal cancer subclassified by tumor-infiltrating myeloid cells: A prospective cohort study

吸烟与基于肿瘤浸润髓系细胞的结直肠癌长期发病风险：一项前瞻性队列研究

Environmental Pollution
IF7.3
2026-04-270
OAAI
Satoko Ugai; Hiroki Mizuno; Kosuke Matsuda; Atsushi Kondo; Yuxue Zhong; Nobuhiro Nakazawa; Satoshi Miyahara; Naoka Murakami; Sara A. Väyrynen; Andrew T. Chan; Mingyang Song; Marios Giannakis; Jeffrey A. Meyerhardt; Juha P. Väyrynen; Jonathan A. Nowak; Shuji Ogino; Tomotaka Ugai
Early-Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

早发性消化系统癌症：风险因素及跨器官位点的临床病理和分子特征

Cancer Science
IF4.3
2026-03-180
OAAI
Nobuhiro Nakazawa; Satoko Ugai; Atsushi Kondo; Kosuke Matsuda; Shu Kato; Genki Usui; Shiori Tanaka; Hwa-Young Lee; Xinyuan Zhang; Hideo Miyagawa; Mai Chan Lau; Hiroshi Saeki; Yukihide Kanemitsu; Andrew T. Chan; Shuji Ogino; Minkyo Song; Juha P. Väyrynen; Tomotaka Ugai
Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes

结直肠癌肿瘤的基因组特征：对显著突变基因、通路和生存结局的见解

BMC Cancer
IF3.4
2025-12-180
OAAI
Tabitha A. Harrison; Syed H. Zaidi; Hang Yin; Robert S. Steinfelder; Conghui Qu; Elom K. Aglago; Sonja I. Berndt; Lisa A. Boardman; Hermann Brenner; Daniel D. Buchanan; Peter T. Campbell; Yin Cao; Andrew T. Chan; Stephen J. Chanock; Kimberly F. Doheny; David A. Drew; Jane C. Figueiredo; Amy J. French; Steven Gallinger; Peter Georgeson; Marios Giannakis; Ellen L. Goode; Stephen B. Gruber; Andrea Gsur; Marc J. Gunter; Sophia Harlid; Michael Hoffmeister; Wen-Yi Huang; Meredith AJ. Hullar; Jeroen R. Huyghe; Mark A. Jenkins; Yi Lin; Victor Moreno; Neil Murphy; Polly A. Newcomb; Christina C. Newton; Jonathan A. Nowak; Mireia Obón-Santacana; Shuji Ogino; Tameka Shelford; Mingyang Song; Claire E. Thomas; Amanda E. Toland; Tomotaka Ugai; Caroline Y. Um; Bethany Van Guelpen; Quang M. Trinh; Wei Sun; Thomas J. Hudson; Li Hsu; Ulrike Peters; Amanda I. Phipps
Diverging global incidence trends of early-onset cancers: comparisons with incidence trends of later-onset cancers and mortality trends of early-onset cancers

早期发病癌症的全球发病率趋势呈现趋异：与晚期发病癌症的发病率趋势及早期发病癌症的死亡率趋势的比较

Military Medical Research
IF22.9
2025-11-170
OAAI
Miyu Terashima; Kota Nakayama; Sora Shirai; Satoko Ugai; Hwa-Young Lee; Haruna Matsui; Hiroki Mizuno; Shiori Tanaka; Minkyo Song; Naoko Sasamoto; Ichiro Kawachi; Edward L. Giovannucci; Tomotaka Ugai
Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies

腰围、体型指数与结直肠癌的分子亚型: 四项队列研究的汇总分析

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
2025-02-260
PRE
Chalitsios, Christos V.; Markozannes, Georgios; Papagiannopoulos, Christos; Aglago, Elom K.; Berndt, Sonja I.; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Murphy, Neil; Peters, Ulrike; Phipps, Amanda I.; Tsilidis, Konstantinos K.
Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment

肿瘤-免疫分区与聚类算法：用于识别肿瘤微环境内肿瘤-免疫细胞空间相互作用特征

plos biology
IF3.6
2025-02-180
OA
Lau, Mai Chan; Borowsky, Jennifer; Vayrynen, Juha P.; Haruki, Koichiro; Zhao, Melissa; Dias Costa, Andressa; Gu, Simeng; da Silva, Annacarolina; Ugai, Tomotaka; Arima, Kota; Nguyen, Minh N.; Takashima, Yasutoshi; Yeong, Joe; Tai, David; Hamada, Tsuyoshi; Lennerz, Jochen K.; Fuchs, Charles S.; Wu, Catherine J.; Meyerhardt, Jeffrey A.; Nowak, Jonathan A.
Long-term yogurt intake and colorectal cancer incidence subclassified by Bifidobacterium abundance in tumor

长期摄入酸奶与根据肿瘤中双歧杆菌丰度分亚类的结直肠癌发病率

GUT MICROBES
IF11
2025-02-120
OA
Satoko Ugai; Li Liu; Keisuke Kosumi; Hidetaka Kawamura; Tsuyoshi Hamada; Kosuke Mima; Kota Arima; Kazuo Okadome; Qian Yao; Kosuke Matsuda; Yuxue Zhong; Hiroki Mizuno; Andrew T. Chan; Wendy S. Garrett; Mingyang Song; Marios Giannakis; Edward L. Giovannucci; Xuehong Zhang; Shuji Ogino; Tomotaka Ugai
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing

根据靶向肿瘤测序定义的基因亚型，叶酸摄入量和结直肠癌风险

AMERICAN JOURNAL OF CLINICAL NUTRITION
IF6.9
2024-09-010
OAAI
Aglago, Elom K.; Qu, Conghui; Harlid, Sophia; Phipps, Amanda, I; Steinfelder, Robert S.; Ogino, Shuji; Thomas, Claire E.; Hsu, Li; Toland, Amanda E.; Brenner, Hermann; Berndt, Sonja, I; Buchanan, Daniel; Campbell, Peter; Cao, Yin; Chan, Andrew; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Gallinger, Steven; Georgeson, Ter; Giannakis, Marios; Goode, Ellen L.; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Jenkins, Mark A.; Lynch, Brigid; Moreno, Victor; Murphy, Neil; Newton, Christina; Nowak, Jonathan; Obon-Santacana, Mireia; Sun, Wei; Ugai, Tomotaka; Um, Caroline Y.; Zaidi, Syed H.; Tsilidis, Konstantinos; van Guelpen, Bethany; Peters, Ulrike
Germline genetic regulation of the colorectal tumor immune microenvironment

结直肠肿瘤免疫微环境的种系基因调控

BMC GENOMICS
IF3.7
2024-04-251
OAAI
Schmit, Stephanie L.; Tsai, Ya-Yu; Bonner, Joseph D.; Sanz-Pamplona, Rebeca; Joshi, Amit D.; Ugai, Tomotaka; Lindsey, Sidney S.; Melas, Marilena; McDonnell, Kevin J.; Idos, Gregory E.; Walker, Christopher P.; Qu, Chenxu; Kast, W. Martin; Da Silva, Diane M.; Glickman, Jonathan N.; Chan, Andrew T.; Giannakis, Marios; Nowak, Jonathan A.; Rennert, Hedy S.; Robins, Harlan S.; Ogino, Shuji; Greenson, Joel K.; Moreno, Victor; Rennert, Gad; Gruber, Stephen B.
The Cancer Spectrum Theory

癌症频谱理论

CANCER DISCOVERY
IF33.3
2024-04-041
OA
Lee, Hwa-Young; Song, Minkyo; Stopsack, Konrad H.; Peng, Cheng; Phipps, Amanda I.; Wang, Molin; Ogino, Shuji; Sasamoto, Naoko; Ugai, Tomotaka

研究方向

暂未获取到该数据
S
Shuji Ogino
H 指数:132论文数:1,372被引数:6.5万
M
Marios Giannakis
H 指数:54论文数:725被引数:1.6万
J
Jonathan A. Nowak
H 指数:62论文数:909被引数:1.6万
M
Mingyang Song
H 指数:82论文数:1,186被引数:2.9万
A
Andrew T. Chan
H 指数:135论文数:2,171被引数:7.9万
K
Koichiro Haruki
H 指数:32论文数:418被引数:3,827
J
Jeffrey A. Meyerhardt
H 指数:116论文数:1,054被引数:5.2万
N
Naohiko Akimoto
H 指数:19论文数:125被引数:2,048
J
Juha P. Väyrynen
H 指数:41论文数:303被引数:5,477
K
Kota Arima
H 指数:32论文数:222被引数:3,154