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M

Marios Giannakis

Dana-Farber Cancer Institute and Harvard Medical School

54H指数
724论文数
1.6W被引数
收录论文 111
发表时间
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RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulationRNF43 p.G659fs通过PI3K/AKT/mTOR信号通路和HLA-E上调导致MSI-high结直肠癌中自然杀伤细胞功能障碍
errScience Advances
IF12.5
err2026-09-23
err0
errOAAI
errPushpamali De Silva; Samantha Fitzgerald; Jules Cazaubiel; Kristin Qian; Matan Hofree; Jia-Ren Lin; Roxanne Pelletier; Mariana Lopez Leon; Phuong Vu Mai Ho; Yasutoshi Takashima; Juha P Väyrynen; Kosuke Matsuda; Tomotaka Ugai; Dane Ford-Roshon; Pratyusha Bala; Nir Hacohen; Kimmie Ng; Jonathan A. Nowak; Shuji Ogino; Peter K. Sorger; Marios Giannakis
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Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial奥拉帕尼与尼沃鲁单抗联合治疗微卫星稳定型结直肠癌：一项1/2期临床试验
errNature Communications
IF15.7
err2026-07-23
err0
errOAAI
errEric S. Christenson; Jeremiah A. Wala; Rose Parkinson; Natalie B. Collins; Christopher Jakubowski; Jia-Ren Lin; Kristin Qian; Jiayun Lu; Hao Wang; Won Jin Ho; Sabrina Chan; Ewa Kulikowicz; Rachel Klein; Yvette Cetasaan; Emma Johnson; Maureen Berg; Jeffrey A. Meyerhardt; Dung T. Le; Benjamin L. Schlechter; Ilene Browner; Lei Zheng; Harshabad Singh; Ross Donehower; Elizabeth M. Jaffee; Peter K. Sorger; Marios Giannakis; Nilofer Azad
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Gemcitabine and nab-paclitaxel with or without the VDR agonist paricalcitol for metastatic pancreatic cancer: a randomized, multiarm, run-in phase trial吉西他滨和nab-紫杉醇联合或不联合VDR激动剂帕立骨化醇治疗转移性胰腺癌: 一项随机，多臂，磨合期试验
errNature Cancer
IF28.5
err2026-05-25
err0
PREAI
errKimberly J. Perez; Andressa Dias Costa; Alexander Jordan; Thomas B. Karasic; Dalia Elganainy; Suryun Kim; Chen Yuan; Dan Y. Gui; Runzi Tan; Sung Chul Hong; Xi Wang; Simona Cristea; Emma Coleman; Morgan Truitt; Tae Gyu Oh; Hui Zheng; C. Sloane Furniss; Lauren Brais; Alexandra Bird; Josh Remland; Vasilena Gocheva; Jennifer S. Thalappillil; Mark Anderson; James M. Cleary; Andrea Enzinger; Marios Giannakis; Kimmie Ng; Douglas A. Rubinson; Benjamin Schlechter; Rishi Surana; Harshabad Singh; Thomas Abrams; Ursina Teitelbaum; Natallia Izgur; Eliezer Allen; Peter S. Winter; Srivatsan Raghavan; Jen Jen Yeh; Daniel Von Hoff; Christopher Liddle; Michael Downes; Ronald M. Evans; Peter O’Dwyer; Andrew Aguirre; Jonathan A. Nowak; Brian M. Wolpin
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Cigarette smoking and long-term incidence of colorectal cancer subclassified by tumor-infiltrating myeloid cells: A prospective cohort study吸烟与基于肿瘤浸润髓系细胞的结直肠癌长期发病风险：一项前瞻性队列研究
errEnvironmental Pollution
IF7.3
err2026-04-27
err0
errOAAI
errSatoko Ugai; Hiroki Mizuno; Kosuke Matsuda; Atsushi Kondo; Yuxue Zhong; Nobuhiro Nakazawa; Satoshi Miyahara; Naoka Murakami; Sara A. Väyrynen; Andrew T. Chan; Mingyang Song; Marios Giannakis; Jeffrey A. Meyerhardt; Juha P. Väyrynen; Jonathan A. Nowak; Shuji Ogino; Tomotaka Ugai
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Tumor vessel phenotype in colorectal cancer microenvironment according to age at diagnosis结直肠癌微环境中肿瘤血管表型与诊断年龄的关系
errBritish Journal of Cancer
IF6.8
err2026-03-01
err1
errOAAI
errMatsuda, Kosuke; Ugai, Satoko; Miyahara, Satoshi; Yao, Qian; Cazaubiel, Jules; Nakazawa, Nobuhiro; Higashioka, Mayu; Zhong, Yuxue; Chan, Andrew T.; Meyerhardt, Jeffrey A.; Ng, Kimmie; Song, Mingyang; Vayrynen, Juha P.; Nowak, Jonathan A.; Giannakis, Marios; Ugai, Tomotaka; Ogino, Shuji
err分享
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Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes结直肠癌肿瘤的基因组特征：对显著突变基因、通路和生存结局的见解
errBMC Cancer
IF3.4
err2025-12-18
err0
errOAAI
errTabitha A. Harrison; Syed H. Zaidi; Hang Yin; Robert S. Steinfelder; Conghui Qu; Elom K. Aglago; Sonja I. Berndt; Lisa A. Boardman; Hermann Brenner; Daniel D. Buchanan; Peter T. Campbell; Yin Cao; Andrew T. Chan; Stephen J. Chanock; Kimberly F. Doheny; David A. Drew; Jane C. Figueiredo; Amy J. French; Steven Gallinger; Peter Georgeson; Marios Giannakis; Ellen L. Goode; Stephen B. Gruber; Andrea Gsur; Marc J. Gunter; Sophia Harlid; Michael Hoffmeister; Wen-Yi Huang; Meredith AJ. Hullar; Jeroen R. Huyghe; Mark A. Jenkins; Yi Lin; Victor Moreno; Neil Murphy; Polly A. Newcomb; Christina C. Newton; Jonathan A. Nowak; Mireia Obón-Santacana; Shuji Ogino; Tameka Shelford; Mingyang Song; Claire E. Thomas; Amanda E. Toland; Tomotaka Ugai; Caroline Y. Um; Bethany Van Guelpen; Quang M. Trinh; Wei Sun; Thomas J. Hudson; Li Hsu; Ulrike Peters; Amanda I. Phipps
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Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study身体活动与结直肠癌分子亚型：一项合并的观察性分析和孟德尔随机化研究
errJNCI CANCER SPECTRUM
IF4.1
err2025-12-01
err0
PREAI
errChalitsios, Christos, V; Markozannes, Georgios; Aglago, Elom K.; Berndt, Sonja, I; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Murphy, Neil; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Schoen, Robert E.; Woods, Michael O.; Brenner, Hermann; Andreson, Laura; Pellatt, Andrew J.; Peters, Ulrike; Phipps, Amanda, I; Tsilidis, Konstantinos K.
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Unique role of the prospective cohort incident-tumor biobank method in etiological research前瞻性队列研究中新发肿瘤生物样本库方法在病因学研究中的独特作用
errThe Lancet Regional Health - Americas
IF0
err2025-11-07
err0
errOAAI
errShuji Ogino; Alpa V. Patel; Satoko Ugai; Marios Giannakis; Tomotaka Ugai
err分享
err收藏
Comprehensive Analysis of BRCA1/2 mutations, “BRCAness” and PARP inhibitors in Melanoma.BRCA1/2突变、“BRCAness”及PARP抑制剂在黑色素瘤中的综合分析。
errcritical reviews in oncology hematology
IF0
err2025-09-20
err0
PREAI
errDimitrios Stylianakis; Ioannis Stylianakis; Haris Annette Benjamin; Serafina Martella; Andreas Tziotis; Benedetta Pellegrino; Pushpamali De Silva; Marios Giannakis; Fabiana Perrone; Matteo Lambertini; Cinzia Solinas; Nerina Denaro
err分享
err收藏
Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies
errCANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
IF3.4
err2025-02-26
err0
PREAI
errChalitsios, Christos V.; Markozannes, Georgios; Papagiannopoulos, Christos; Aglago, Elom K.; Berndt, Sonja I.; Buchanan, Daniel D.; Campbell, Peter T.; Cao, Yin; Chan, Andrew T.; Dimou, Niki; Drew, David A.; French, Amy J.; Georgeson, Peter; Giannakis, Marios; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Hsu, Li; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Lynch, Brigid M.; Moreno, Victor; Newton, Christina C.; Nowak, Jonathan A.; Obon-Santacana, Mireia; Ogino, Shuji; Qu, Conghui; Schmit, Stephanie L.; Steinfelder, Robert S.; Sun, Wei; Thomas, Claire E.; Toland, Amanda E.; Trinh, Quang M.; Ugai, Tomotaka; Um, Caroline Y.; Van Guelpen, Bethany; Zaidi, Syed H.; Murphy, Neil; Peters, Ulrike; Phipps, Amanda I.; Tsilidis, Konstantinos K.
err分享
err收藏
Long-term yogurt intake and colorectal cancer incidence subclassified by Bifidobacterium abundance in tumor长期摄入酸奶与根据肿瘤中双歧杆菌丰度分亚类的结直肠癌发病率
errGUT MICROBES
IF11
err2025-02-12
err0
errOAAI
errSatoko Ugai; Li Liu; Keisuke Kosumi; Hidetaka Kawamura; Tsuyoshi Hamada; Kosuke Mima; Kota Arima; Kazuo Okadome; Qian Yao; Kosuke Matsuda; Yuxue Zhong; Hiroki Mizuno; Andrew T. Chan; Wendy S. Garrett; Mingyang Song; Marios Giannakis; Edward L. Giovannucci; Xuehong Zhang; Shuji Ogino; Tomotaka Ugai
err分享
err收藏
Rethinking the rise of early-onset gastrointestinal cancers: a call to action
errJNCI CANCER SPECTRUM
IF4.1
err2025-01-15
err0
errOAAI
errWeinberg, Benjamin A.; Murphy, Caitlin C.; Freyer, David R.; Greathouse, K. Leigh; Blancato, Jan K.; Stoffel, Elena M.; Drewes, Julia L.; Blaes, Anne; Salsman, John M.; You, Y. Nancy; Arem, Hannah; Mukherji, Reetu; Kanth, Priyanka; Hu, Xin; Fabrizio, Anne; Hartley, Marion L.; Giannakis, Marios; Marshall, John L.
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An Empirical Dietary Pattern Associated With the Gut Microbial Features in Relation to Colorectal Cancer Risk与结肠直肠癌风险相关的肠道微生物特征相关的经验饮食模式
errGASTROENTEROLOGY
IF25.1
err2024-12-01
err1
PREAI
errWang, Kai; Lo, Chun-Han; Mehta, Raaj S.; Nguyen, Long H.; Wang, Yiqing; Ma, Wenjie; Ugai, Tomotaka; Kawamura, Hidetaka; Ugai, Satoko; Takashima, Yasutoshi; Mima, Kosuke; Arima, Kota; Okadome, Kazuo; Giannakis, Marios; Sears, Cynthia L.; Meyerhardt, Jeffrey A.; Ng, Kimmie; Segata, Nicola; Izard, Jacques; Rimm, Eric B.; Garrett, Wendy S.; Huttenhower, Curtis; Giovannucci, Edward L.; Chan, Andrew T.; Ogino, Shuji; Song, Mingyang
err分享
err收藏
Phase 2 Trial Testing The PARP Inhibitor Niraparib In Patients With Advanced Pancreatic Cancer with Pathogenic Variants In BRCA 1, BRCA2, PALB2, ATM and CHEK2
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errHuffman, Brandon M.; Crowdis, Jett; Yurgelun, Matthew B.; Horick, Nora; Li, Yvonne; Huy Nguyen; Parmar, Kalindi; Kochupurakkal, Bose S.; Enzinger, Andrea; Giannakis, Marios; McCleary, Nadine; Ng, Kimmie; Patel, Anuj K.; Perez, Kimberly J.; Rubinson, Douglas A.; Schlechter, Benjamin L.; Singh, Harshabad; Lam, Helen; Ramsey, Kaitlyn; Andrews, Elizabeth; Culnane, Leigh; Bullock, Andrea; Rattani, Ahmed; Clark, Jeffrey; Peters, Mary Linton; Wolpin, Brian M.; D'Andrea, Alan D.; Shapiro, Geoffrey I.; Aguirre, Andrew J.; Cleary, James M.
err分享
err收藏
Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing
errAMERICAN JOURNAL OF CLINICAL NUTRITION
IF6.9
err2024-09-01
err0
errOAAI
errAglago, Elom K.; Qu, Conghui; Harlid, Sophia; Phipps, Amanda, I; Steinfelder, Robert S.; Ogino, Shuji; Thomas, Claire E.; Hsu, Li; Toland, Amanda E.; Brenner, Hermann; Berndt, Sonja, I; Buchanan, Daniel; Campbell, Peter; Cao, Yin; Chan, Andrew; Drew, David A.; Figueiredo, Jane C.; French, Amy J.; Gallinger, Steven; Georgeson, Ter; Giannakis, Marios; Goode, Ellen L.; Gruber, Stephen B.; Gunter, Marc J.; Harrison, Tabitha A.; Hoffmeister, Michael; Huang, Wen-Yi; Hullar, Meredith A. J.; Huyghe, Jeroen R.; Jenkins, Mark A.; Lynch, Brigid; Moreno, Victor; Murphy, Neil; Newton, Christina; Nowak, Jonathan; Obon-Santacana, Mireia; Sun, Wei; Ugai, Tomotaka; Um, Caroline Y.; Zaidi, Syed H.; Tsilidis, Konstantinos; van Guelpen, Bethany; Peters, Ulrike
err分享
err收藏
Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
errCANCER DISCOVERY
IF33.3
err2024-08-12
err0
errOAAI
errLoi, Patrick; Schade, Amy E.; Rodriguez, Carrie L.; Krishnan, Anjana; Perurena, Naiara; Nguyen, Van T. M.; Xu, Yilin; Watanabe, Marina; Davis, Rachel A.; Gardner, Alycia; Pilla, Natalie F.; Mattioli, Kaia; Popow, Olesja; Gunduz, Nuray; Lannagan, Tamsin R. M.; Fitzgerald, Samantha; Sicinska, Ewa T.; Lin, Jia-Ren; Tan, William; Brais, Lauren K.; Haigis, Kevin M.; Giannakis, Marios; Ng, Kimmie; Santagata, Sandro; Helin, Kristian; Sansom, Owen J.; Cichowski, Karen
err分享
err收藏
Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma
errCLINICAL MICROBIOLOGY AND INFECTION
IF8.5
err2024-05-01
err4
PREAI
errTakashima, Yasutoshi; Kawamura, Hidetaka; Okadome, Kazuo; Ugai, Satoko; Haruki, Koichiro; Arima, Kota; Mima, Kosuke; Akimoto, Naohiko; Nowak, Jonathan A.; Giannakis, Marios; Garrett, Wendy S.; Sears, Cynthia L.; Song, Mingyang; Ugai, Tomotaka; Ogino, Shuji
err分享
err收藏
Germline genetic regulation of the colorectal tumor immune microenvironment结直肠肿瘤免疫微环境的种系基因调控
errBMC GENOMICS
IF3.7
err2024-04-25
err1
errOAAI
errSchmit, Stephanie L.; Tsai, Ya-Yu; Bonner, Joseph D.; Sanz-Pamplona, Rebeca; Joshi, Amit D.; Ugai, Tomotaka; Lindsey, Sidney S.; Melas, Marilena; McDonnell, Kevin J.; Idos, Gregory E.; Walker, Christopher P.; Qu, Chenxu; Kast, W. Martin; Da Silva, Diane M.; Glickman, Jonathan N.; Chan, Andrew T.; Giannakis, Marios; Nowak, Jonathan A.; Rennert, Hedy S.; Robins, Harlan S.; Ogino, Shuji; Greenson, Joel K.; Moreno, Victor; Rennert, Gad; Gruber, Stephen B.
err分享
err收藏
Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable ( MSS) colorectal cancer (CRC)
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errChristenson, Eric S.; Wala, Jeremiah A.; Parkinson, Rose; Collins, Natalie B.; Jakubowski, Christopher; Lin, Jea-Ren; Wang, Hao; Ho, Won Jin; Chan, Sabrina; Klein, Rachel; Cetasaan, Yvette; Johnson, Emma; Berg, Maureen; Meyerhardt, Jeffrey; Schlechter, Benjamin; Singh, Harshabad; Sorger, Peter K.; Giannakis, Marios; Azad, Nilofer
err分享
err收藏
Alcohol and colorectal cancer risk, subclassified by mutational signatures of DNA mismatch repair deficiency
errJNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
err2024-04-04
err1
errOAAI
errFang, Aiping; Ugai, Tomotaka; Gurjao, Carino; Zhong, Rong; Liu, Zhenhua; Zhang, Xinyuan; Wang, Peilu; Nowak, Jonathan; Wang, Molin; Giannakis, Marios; Ogino, Shuji; Zhang, Xuehong; Giovannucci, Edward
err分享
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