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M

Monika A. Davare

oregon health & science university
H指数:38
被引数:6,344

个人简介

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Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations (vol 4, pg 1345, 2023)
NATURE CANCER
IF28.5
2023-10-091
OAAI
Miyazaki, Isao; Odintsov, Igor; Ishida, Keiji; Lui, Allan J. W.; Kato, Masanori; Suzuki, Tatsuya; Zhang, Tom; Wakayama, Kentaro; Kurth, Renate I.; Cheng, Ryan; Fujita, Hidenori; Delasos, Lukas; Vojnic, Morana; Khodos, Inna; Yamada, Yukari; Ishizawa, Kota; Mattar, Marissa S.; Funabashi, Kaoru; Chang, Qing; Ohkubo, Shuichi; Yano, Wakako; Terada, Ryuichiro; Giuliano, Claudio; Lu, Yue Christine; Bonifacio, Annalisa; Kunte, Siddharth; Davare, Monika A.; Cheng, Emily H.; de Stanchina, Elisa; Lovati, Emanuela; Iwasawa, Yoshikazu; Ladanyi, Marc; Somwar, Romel
Vepafestinib is a pharmacologically advanced RET-selective inhibitor with high CNS penetration and inhibitory activity against RET solvent front mutations
NATURE CANCER
IF28.5
2023-09-2111
OAAI
Miyazaki, Isao; Odintsov, Igor; Ishida, Keiji; Lui, Allan J. W.; Kato, Masanori; Suzuki, Tatsuya; Zhang, Tom; Wakayama, Kentaro; Kurth, Renate I.; Cheng, Ryan; Fujita, Hidenori; Delasos, Lukas; Vojnic, Morana; Khodos, Inna; Yamada, Yukari; Ishizawa, Kota; Mattar, Marissa S.; Funabashi, Kaoru; Chang, Qing; Ohkubo, Shuichi; Yano, Wakako; Terada, Ryuichiro; Giuliano, Claudio; Lu, Yue Christine; Bonifacio, Annalisa; Kunte, Siddharth; Davare, Monika A.; Cheng, Emily H.; de Stanchina, Elisa; Lovati, Emanuela; Iwasawa, Yoshikazu; Ladanyi, Marc; Somwar, Romel
NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations

NVL-520是ROS1融合和继发性耐药突变的选择性，TRK保留和脑渗透抑制剂

CANCER DISCOVERY
IF33.3
2022-12-1319
OAAI
Drilon, Alexander; Horan, Joshua C.; Tangpeerachaikul, Anupong; Besse, Benjamin; Ou, Sai-Hong Ignatius; Gadgeel, Shirish M.; Camidge, D. Ross; Wekken, Anthonie J. van der; Nguyen-Phuong, Linh; Acker, Adam; Keddy, Clare; Nicholson, Katelyn S.; Yoda, Satoshi; Mente, Scot; Sun, Yuting; Soglia, John R.; Kohl, Nancy E.; Porter, James R.; Shair, Matthew D.; Zhu, Viola; Davare, Monika A.; Hata, Aaron N.; Pelish, Henry E.; Lin, Jessica J.
RET inhibition in novel patient-derived models of RET fusion-positive lung adenocarcinoma reveals a role for MYC upregulation

RET融合阳性肺腺癌的新型患者衍生模型中的RET抑制揭示了MYC上调的作用

DISEASE MODELS & MECHANISMS
IF3.3
2021-02-1112
OAAI
Hayashi, Takuo; Odintsov, Igor; Smith, Roger S.; Ishizawa, Kota; Liu, Allan J. W.; Delasos, Lukas; Kurzatkowski, Christopher; Tai, Huichun; Gladstone, Eric; Vojnic, Morana; Kohsaka, Shinji; Suzawa, Ken; Liu, Zebing; Kunte, Siddharth; Mattar, Marissa S.; Khodos, Inna; Davare, Monika A.; Drilon, Alexander; Cheng, Emily; de Stanchina, Elisa; Ladanyi, Marc; Somwar, Romel
Overcoming MET-Dependent Resistance to Selective RET Inhibition in Patients with RET Fusion-Positive Lung Cancer by Combining Selpercatinib with Crizotinib
CLINICAL CANCER RESEARCH
IF10.2
2021-01-0495
OAAI
Rosen, Ezra Y.; Johnson, Melissa L.; Clifford, Sarah E.; Somwar, Romel; Kherani, Jennifer F.; Son, Jieun; Bertram, Arrien A.; Davare, Monika A.; Gladstone, Eric; Ivanova, Elena, V; Henry, Dahlia N.; Kelley, Elaine M.; Lin, Mika; Milan, Marina S. D.; Nair, Binoj C.; Olek, Elizabeth A.; Scanlon, Jenna E.; Vojnic, Morana; Ebata, Kevin; Hechtman, Jaclyn F.; Li, Bob T.; Sholl, Lynette M.; Taylor, Barry S.; Ladanyi, Marc; Janne, Pasi A.; Rothenberg, S. Michael; Drilon, Alexander; Oxnard, Geoffrey R.

研究方向

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R
Romel Somwar
H 指数:48论文数:497被引数:1.2万
A
Alexander Drilon
H 指数:91论文数:1,386被引数:3.8万
B
Brian Druker
H 指数:135论文数:2,590被引数:9.5万
U
Ujwal Shinde
H 指数:39论文数:165被引数:4,149
C
Clare Keddy
H 指数:6论文数:40被引数:415
M
Morana Vojnic
H 指数:12论文数:126被引数:858
K
Kristen L. Jones
H 指数:24论文数:160被引数:2,035
E
Elisa de Stanchina
H 指数:94论文数:1,296被引数:3.9万
C
Catherine Z. Beach
H 指数:6论文数:17被引数:85
L
Ladanyi, Marc
H 指数:0论文数:6被引数:126