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Biolayer interferometry for measuring the kinetics of protein-protein interactions and nanobody binding Bates, Timothy A.; Gurmessa, Sintayehu K.; Weinstein, Jules B.; Trank-Greene, Mila; Wrynla, Xammy Huu; Anastas, Aidan; Anley, Teketay Wassie; Hinchliff, Audrey; Shinde, Ujwal; Burke, John E.; Tafesse, Fikadu G. 分享 收藏
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ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages ESAT-6在吞噬体pH下发生自我缔合,ESAT-6-specific纳米抗体限制了巨噬细胞中结核分枝杆菌的生长 Bates, Timothy A.; Trank-Greene, Mila; Nguyenla, Xammy; Anastas, Aidan; Gurmessa, Sintayehu K.; Merutka, Ilaria R.; Dixon, Shandee D.; Shumate, Anthony; Groncki, Abigail R.; Parson, Matthew A. H.; Ingram, Jessica R.; Barklis, Eric; Burke, John E.; Shinde, Ujwal; Ploegh, Hidde L.; Tafesse, Fikadu G. 分享 收藏
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors Iyer, Sudarshan R.; Nusser, Kevin; Jones, Kristen; Shinde, Pushkar; Keddy, Clare; Beach, Catherine Z.; Aguero, Erin; Force, Jeremy; Shinde, Ujwal; Davare, Monika A. 分享 收藏
Activating missense mutations in ROS1 receptor harbor oncogenic potential and are sensitive to tyrosine kinase inhibition Iyer, Sudarshan R.; Nusser, Kevin; Jones, Kristen; Shinde, Pushkar; Beach, Catherine Z.; Keddy, Clare; Aguero, Erin; Force, Jeremy; Shinde, Ujwal; Davare, Monika A. 分享 收藏
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The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing Chen, Yingxiao; Li, Yanping; Dai, Roselyn S.; Savage, Jonathan C.; Shinde, Ujwal; Klimek, John; David, Larry L.; Young, Emma A.; Hafner, Markus; Sears, Rosalie C.; Sun, Xiao-Xin; Dai, Mu-Shui 分享 收藏
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Signaling-Biased and Constitutively Active Dopamine D2 Receptor Variant Rodriguez-Contreras, Dayana; Condon, Alec F.; Buck, David C.; Asad, Naeem; Dore, Timothy M.; Verbeek, Dineke S.; Tijssen, Marina A. J.; Shinde, Ujwal; Williams, John T.; Neve, Kim A. 分享 收藏
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NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors Somwar, Romel; Hofmann, Nicolle E.; Smith, Bryan; Odintsov, Igor; Vojnic, Morana; Linkov, Irina; Tam, Ashley; Khodos, Inna; Mattar, Marissa S.; de Stanchina, Elisa; Flynn, Daniel; Ladanyi, Marc; Drilon, Alexander; Shinde, Ujwal; Davare, Monika A. 分享 收藏
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Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes Hosseini, Mona M.; Kurtz, Stephen E.; Abdelhamed, Sherif; Mahmood, Shawn; Davare, Monika A.; Kaempf, Andy; Elferich, Johannes; McDermott, Jason E.; Liu, Tao; Payne, Samuel H.; Shinde, Ujwal; Rodland, Karin D.; Mori, Motomi; Druker, Brian J.; Singer, Jack W.; Agarwal, Anupriya 分享 收藏
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