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Bhavana Chhunchha

University of Nebraska Medical Center

H指数:17

被引数:1,187

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Loss of Peroxiredoxin 6 Drives Age-Related Klf9/NF-κB/Nlrp3 Inflammasome Activation and Pyroptosis: Therapeutic Rescue by Prdx6

过氧化物还原酶6的缺失驱动与年龄相关的Klf9/NF-κB/Nlrp3炎性小体激活和焦亡：Prdx6的疗法拯救

IF6.6

2026-04-230

OAAI

TXNIP-Deficiency and Prdx6 Delivery Inhibit Aging/Oxidative Stress–Driven TXNIP-Nlrp3 Inflammasome Activation and Mitigate Pyroptosis in Lens Epithelial Cells

TXNIP缺乏和Prdx6递送抑制衰老/氧化应激驱动的TXNIP-Nlrp3炎性体激活并减轻晶状体上皮细胞的焦亡

IF6.6

2026-01-280

OAAI

Topical Instillation of N-Acetylcysteine and N-Acetylcysteine Amide Impedes Age-Related Lens Opacity in Mice

N-乙酰半胱氨酸和N-乙酰半胱氨酸酰胺的局部滴注延缓小鼠年龄相关性晶状体混浊

IF4.8

2025-03-190

OA

NLRP3 Inflammasome and Inflammatory Response in Aging Disorders: The Entanglement of Redox Modulation in Different Outcomes

NLRP3炎性小体与衰老相关疾病中的炎症反应：不同结局中氧化还原调控的交织

IF5.2

2025-01-010

OAAI

DNA methylation as an epigenetic mechanism in the regulation of LEDGF expression and biological response in aging and oxidative stress

CELL DEATH DISCOVERY

IF7

2024-06-225

OAAI

EAAT5 glutamate transporter rapidly binds glutamate with micromolar affinity in mouse rods

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2023-07-214

PRE

Hydralazine Revives Cellular and Ocular Lens Health-Span by Ameliorating the Aging and Oxidative-Dependent Loss of the Nrf2-Activated Cellular Stress Response

IF6.6

2023-01-067

OAAI

Obligatory Role of AMPK Activation and Antioxidant Defense Pathway in the Regulatory Effects of Metformin on Cellular Protection and Prevention of Lens Opacity

IF5.2

2022-09-279

OAAI

Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species

IF5.2

2022-04-0814

OAAI

Engineered Sumoylation-Deficient Prdx6 Mutant Protein-Loaded Nanoparticles Provide Increased Cellular Defense and Prevent Lens Opacity

IF6.6

2021-08-045

OAAI

Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6

IF5.2

2020-08-0858

OAAI

Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells

IF5.2

2019-09-2746

OAAI

Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress

IF3.9

2018-09-1226

OAAI

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

SCIENTIFIC REPORTS

IF3.9

2017-10-26180

OAAI

Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species

CELL DEATH DISCOVERY

IF7

2017-09-1150

OAAI

Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation

CELL DEATH & DISEASE

IF9.6

2017-01-0526

OAAI

Delivery of a protein transduction domain-mediated Prdx6 protein ameliorates oxidative stress-induced injury in human and mouse neuronal cells

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2016-01-0131

OAAI

Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription

IF4.2

2014-07-0128

OAAI

Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-κB regulation

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

IF4.7

2013-04-0185

OAAI

Lens epithelium-derived growth factor deSumoylation by Sumo-specific protease-1 regulates its transcriptional activation of small heat shock protein and the cellular response

IF4.2

2012-07-1617

OA