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Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis 高反应性B细胞通过T细胞介导的清除来抑制自身炎症和淋巴瘤发生。 Diehl, Carina; Soberon, Valeria; Bayguen, Seren; Chu, Yuanyuan; Mandelbaum, Jonathan; Kraus, Laura; Engleitner, Thomas; Rudelius, Martina; Fangazio, Marco; Daniel, Christoph; Bortoluzzi, Sabrina; Helmrath, Sabine; Singroul, Pankaj; Goelling, Vanessa; Barrios, Francisco Osorio; Seyhan, Goenul; Osswald, Lena; Kober-Hasslacher, Maike; Zeng, Theodor; Oellinger, Rupert; Afzali, Ali M.; Korn, Thomas; Honarpisheh, Mohsen; Lech, Maciej; Ul Ain, Qurrat; Pircher, Joachim; Imsirovic, Vanna; Jeleneic, Vedrana; Wensveen, Felix M.; Passerini, Verena; Baerthel, Stefanie; Dominguez-Sola, David; Ollinger, Rupert; Saur, Dieter; Steiger, Katja; Rad, Roland; Pasqualucci, Laura; Weigert, Oliver; Schmidt-Supprian, Marc 分享 收藏
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MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis Yu, Chuanjiang; Shen, Qiong; Holmes, Antony B.; Mo, Tongwei; Tosato, Anna; Soni, Rajesh Kumar; Corinaldesi, Clarissa; Koul, Sanjay; Pasqualucci, Laura; Hussein, Shafinaz; Forouhar, Farhad; Dalla-Favera, Riccardo; Basso, Katia 分享 收藏
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KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells Vlasevska, Sofija; Garcia-Ibanez, Laura; Duval, Romain; Holmes, Antony B.; Jahan, Rahat; Cai, Bowen; Kim, Andrew; Mo, Tongwei; Basso, Katia; Soni, Rajesh K.; Bhagat, Govind; Dalla-Favera, Riccardo; Pasqualucci, Laura 分享 收藏
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DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice DNA损伤诱导的保守ATM/ATR位点T855的CtIP磷酸化促进小鼠的淋巴瘤发生 Wang, Xiaobin S.; Menolfi, Demis; Wu-Baer, Foon; Fangazio, Marco; Meyer, Stefanie N.; Shao, Zhengping; Wang, Yunyue; Zhu, Yimeng; Lee, Brian J.; Estes, Verna M.; Cupo, Olivia M.; Gautier, Jean; Pasqualucci, Laura; Dalla-Favera, Riccardo; Baer, Richard; Zha, Shan 分享 收藏
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Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma 弥漫性大b细胞淋巴瘤hla-i缺失和免疫逃逸的遗传机制 Fangazio, Marco; Ladewig, Erik; Gomez, Karen; Garcia-Ibanez, Laura; Kumar, Rahul; Teruya-Feldstein, Julie; Rossi, Davide; Filip, Ioan; Pan-Hammarstrom, Qiang; Inghirami, Giorgio; Boldorini, Renzo; Ott, German; Staiger, Annette M.; Chapuy, Bjorn; Gaidano, Gianluca; Bhagat, Govind; Basso, Katia; Rabadan, Raul; Pasqualucci, Laura; Dalla-Favera, Riccardo 分享 收藏
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities Fluemann, Ruth; Rehkaemper, Tim; Nieper, Pascal; Pfeiffer, Pauline; Holzem, Alessandra; Klein, Sebastian; Bhatia, Sanil; Kochanek, Moritz; Kisis, Ilmars; Pelzer, Benedikt W.; Ahlert, Heinz; Hauer, Julia; Guerreiro, Alexandra da Palma; Ryan, Jeremy A.; Reimann, Maurice; Riabinska, Arina; Wiederstein, Janica; Krueger, Marcus; Deckert, Martina; Altmueller, Janine; Klatt, Andreas R.; Frenzel, Lukas P.; Pasqualucci, Laura; Beguelin, Wendy; Melnick, Ari M.; Sander, Sandrine; Montesinos-Rongen, Manuel; Brunn, Anna; Lohneis, Philipp; Buettner, Reinhard; Kashkar, Hamid; Borkhardt, Arndt; Letai, Anthony; Persigehl, Thorsten; Peifer, Martin; Schmitt, Clemens A.; Reinhardt, Hans Christian; Knittel, Gero 分享 收藏
Genomic Characterization of HIV-Associated Plasmablastic Lymphoma Identifies Pervasive Mutations in the JAK-STAT Pathway Liu, Zhaoqi; Filip, Ioan; Gomez, Karen; Engelbrecht, Dewaldt; Meer, Shabnum; Lalloo, Pooja N.; Patel, Pareen; Perner, Yvonne; Zhao, Junfei; Wang, Jiguang; Pasqualucci, Laura; Rabadan, Raul; Willem, Pascale 分享 收藏
Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome Holmes, Antony B.; Corinaldesi, Clarissa; Shen, Qiong; Kumar, Rahul; Compagno, Nicolo; Wang, Zhong; Nitzan, Mor; Grunstein, Eli; Pasqualucci, Laura; Dalla-Favera, Riccardo; Basso, Katia 分享 收藏
Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization RNA剪接因子SF3B1的突变通过MYC稳定促进肿瘤发生 Liu, Zhaoqi; Yoshimi, Akihide; Wang, Jiguang; Cho, Hana; Lee, Stanley Chun-Wei; Ki, Michelle; Bitner, Lillian; Chu, Timothy; Shah, Harshal; Liu, Bo; Mato, Anthony R.; Ruvolo, Peter; Fabbri, Giulia; Pasqualucci, Laura; Abdel-Wahab, Omar; Rabadan, Raul 分享 收藏
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