Lawrence Shapiro

Columbia University Vagelos College of Physicians and Surgeons

H指数:92

被引数:3.3万

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Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

经典抗体采用不同的结合模式识别病毒糖衣盾

Advanced Science

IF14.1

2026-08-150

Jiaxuan Cheng; Evan M. Cale; Amirabbas Maghsoudi; Matthew S. Sutton; Nancy S. Longo; Rebecca A. Gillespie; Lingshu Wang; Ivan Kosik; Sue Chong; Atsuhiro Yasuhara; Tatsiana Bylund; Arne Schön; Prabhanshu Tripathi; Yaroslav Tsybovsky; Haotian Lei; Nicholas C. Morano; Allison B. Lupatkin; Abraham J. Morton; Zabrina C. Lang; Jordan E. Becker; Isabella R. Frascilla; Myungjin Lee; Ning Li; Cuiping Liu; Ryan S. Roark; Chen-Hsiang Shen; I-Ting Teng; David J. Van Wazer; Danyi Wang; Lingyuan Wu; Goran Ahlsen; Mike Castro; Haijuan Du; Michael J. Ernandes; Tiansheng Li; Bob C. Lin; Mark K. Louder; Krisha McKee; Jonah S. Merriam; Sijy O'Dell; Li Ou; Sergei Pletnev; David Prikryl; Qi Qiu; Sarah Rubin; Mallika Sastry; Stephen D. Schmidt; Asif Shajahan; Andrea R. Shiakolas; Sanjay Srivatsan; Baoshan Zhang; Qiong Zhou; Mark Connors; Jason G. Gall; Yicheng Guo; Rick K. Huang; Yaoxing Huang; Richard A. Koup; Q. Paula Lei; John R. Mascola; Reda Rawi; Leonid Serebryannyy; Lawrence Shapiro; Zizhang Sheng; David D. Ho; Patrick C. Wilson; Jonathan W. Yewdell; Theodore C. Pierson; Masaru Kanekiyo; Nicole A. Doria-Rose; Peter D. Kwong; Tongqing Zhou

Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

增强B细胞初始刺激诱导广泛中和HIV-1顶点抗体

Nature

IF48.5

2026-06-300

PRE

Lorie Marchitto; Kshitij Wagh; Ryan S. Roark; Severin Coleon; Hui Li; Ashwin N. Skelly; Michael P. Hogarty; Rumi Habib; Wenge Ding; Kasirajan Ayyanathan; Weimin Liu; Zizhang Sheng; Yicheng Guo; Joena Bal; Lena M. Smith; Laura L. Sutherland; Younghoon Park; Andrew J. Connell; Frederic Bibollet-Ruche; Emily Lewis; Samantha J. Plante; Macy J. Akeley; Jinery Lora; Chengyan Zhao; John W. Carey; Christian L. Martella; Yingying Li; Mary S. Campion; Melinda G. Lituchy; Rebecca A. Osbaldeston; Colette G. Gordon; Amie Albertus; Justin Su; Chiaki Noguchi; Ying K. Tam; Christopher Barbosa; Bo Liang; Khaled Amereh; Xuduo Li; Agnes A. Walsh; Darrell J. Irvine; Raiees Andrabi; Robert J. Edwards; Edward F. Kreider; Drew Weissman; Lawrence Shapiro; Peter D. Kwong; Bette T. Korber; Barton F. Haynes; Kevin O. Saunders; Beatrice H. Hahn; George M. Shaw

Neutralizing antibodies elicited in nonhuman primates by an enterovirus D68 virus-like particle vaccine target receptor binding sites

非人灵长类动物中由肠道病毒D68病毒样颗粒疫苗诱导的中和抗体靶向受体结合位点

Science Translational Medicine

IF14.6

2026-06-030

PREAI

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development

Env-antibody共进化识别B细胞初始为HIV V2顶点广谱中和抗体发展的主要瓶颈

Science Immunology

IF16.3

2026-02-130

PRE

Rumi Habib; Ryan S. Roark; Hui Li; Andrew Jesse Connell; Michael P. Hogarty; Kshitij Wagh; Shuyi Wang; Lorie Marchitto; Ashwin N. Skelly; John W. Carey; Kirsten J. Sowers; Kasirajan Ayyanathan; Samantha J. Plante; Frederic Bibollet-Ruche; Younghoon Park; Colby J. Agostino; Ajay Singh; Christian L. Martella; Emily Lewis; Juliette M. Rando; Neha Chohan; Jinery Lora; Wenge Ding; Mary S. Campion; Chengyan Zhao; Weimin Liu; Yingying Li; Xuduo Li; Bo Liang; Rohan Roy Chowdhury; Khaled Amereh; Elizabeth Van Itallie; Zizhang Sheng; Amrit R. Ghosh; Katharine J. Bar; Wilton B. Williams; Kevin Wiehe; Kevin O. Saunders; Robert J. Edwards; Derek W. Cain; Mark G. Lewis; Facundo D. Batista; Dennis R. Burton; Raiees Andrabi; Daniel W. Kulp; Barton F. Haynes; Bette Korber; Lawrence Shapiro; Peter D. Kwong; Beatrice H. Hahn; George M. Shaw

Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization

单次大剂量免疫后，恒河猴V2尖峰基因敲入小鼠模型中快速获得的HIV-1中和广度

Science Immunology

IF16.3

2026-02-130

PRE

Amrit Raj Ghosh; Rumi Habib; Nitesh Mishra; Ryan S. Roark; Madhav Akauliya; Ali A. Albowaidey; Joel D. Allen; Khaled Amereh; Gabriel Avillion; Maria Bottermann; Bo Liang; Namit Chaudhary; Sean Callaghan; Jonathan Dye; Xuduo Li; Jordan R. Ellis-Pugh; Rohan Roy Chowdhury; Nicole E. James; Xiaotie Liu; Laura Maiorino; Paula M. Villavicencio; Rebecca Nedellec; Prabhgun Oberoi; Kirsten J. Sowers; Younghoon Park; Thavaleak Prum; Linette Rodriguez; Maria Ssozi; Jonathan L. Torres; Agnes A. Walsh; John E. Warner; Stephanie R. Weldon; Liling Xu; Kevin Wiehe; Max Crispin; Andrew B. Ward; Usha Nair; Beatrice H. Hahn; Dennis R. Burton; Lawrence Shapiro; Peter D. Kwong; Darrell J. Irvine; Raiees Andrabi; George M. Shaw; Facundo D. Batista

Prefusion structure, evasion and neutralization of HSV-1 glycoprotein B

Prefusion结构、逃避及HSV-1糖蛋白B的中和

Nature Microbiology

IF19.4

2025-10-310

OAAI

Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth

酵母展示揭示大量突变，这些突变可显著提升融合肽疫苗诱发的抗体，使其对HIV-1的中和能力超过59%的广度。

Vaccines 2025, Vol. 13, Page 1098

IF3.4

2025-10-270

OAAI