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Zizhang Sheng

Columbia University
H指数:49
被引数:1.3万

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Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields

经典抗体采用不同的结合模式识别病毒糖衣盾

2026-08-150
OA
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

增强B细胞初始刺激诱导广泛中和HIV-1顶点抗体

Nature
IF48.5
2026-06-300
PRE
Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development

Env-antibody共进化识别B细胞初始为HIV V2顶点广谱中和抗体发展的主要瓶颈

2026-02-130
PRE
Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth

酵母展示揭示大量突变,这些突变可显著提升融合肽疫苗诱发的抗体,使其对HIV-1的中和能力超过59%的广度。

2025-10-270
OAAI
Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment

单细胞和克隆分析AL淀粉样变性浆细胞及其骨髓微环境

Blood
IF23.1
2025-06-160
PRE
Frequency-potency analysis of IgG plus memory B cells delineates neutralizing antibody responses at single-cell resolution
2024-03-010
OAAI
Single-Cell Profiling of Bone Marrow B Cells and Early B Cell Developmental Disorders Associated With Systemic Lupus Erythematosus
2024-01-304
OAAI
Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking
IMMUNITY
IF26.3
2023-10-0110
OAAI
A fully human monoclonal antibody possesses antibody-dependent cellular cytotoxicity (ADCC) activity against the H1 subtype of influenza A virus by targeting a conserved epitope at the HA1 protomer interface
2023-07-023
PRE
Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5
2022-11-123
OAAI