Adam S. Sperling - Publications, H-index & Citations

Adam S. Sperling

stanford university

34H指数

331论文数

5.9K被引数

收录论文 59

发表时间

Teclistamab versus lenalidomide-dexamethasone in high-risk smoldering multiple myeloma: a randomized phase 2 trial Teclistamab 与来那度胺-地塞米松在高风险冒烟型多发性骨髓瘤中的比较：一项随机II期试验

Nature Medicine

IF50

2026-09-11

OAAI

Omar Nadeem; David M. Cordas dos Santos; Sophie Magidson; Jeffrey Matous; Eva Medvedova; Elizabeth O’Donnell; Robert A. Redd; Yuxin Liu; Shonali Midha; Adam S. Sperling; Frances Arters; Christine Davie; Caroline Ricciardi; Rosa Toenges; Nayda Bidikian; Subear Hussein; Jean-Baptiste Alberge; Sungjae Kim; Lorena Pantano-Rubino; Francesco Corrado; Hannah Ashton; Daniel Addonizio; Siham Mohamed; Ashlee Sturtevant; Marjorie Marto; Amy Bergeron; Francesco Malfona; Kevin Panaro; Paul G. Richardson; Jerome Ritz; Lorenzo Trippa; Irene M. Ghobrial

Macrophage reprogramming, not CD8 T cell dynamics, characterizes durable disease control following PD-1 blockade in smoldering myeloma 巨噬细胞重编程，而非CD8 T细胞动力学，是PD-1阻断后冒烟性骨髓瘤获得持久疾病控制的特点

Leukemia

IF13.4

2026-09-03

PREAI

Noé Perron; Kane Foster; Tarek H. Mouhieddine; Robert A. Redd; Sophie Magidson; Jacqueline Perry; Ashlee Sturtevant; Christine Davie; Caroline Ricciardi; Frances Arters; Marjorie Marto; Amy Goguen; Yuxin Liu; Elizabeth K. O’Donnell; Adam S. Sperling; Jacob P. Laubach; Paul G. Richardson; Gad Getz; Romanos Sklavenitis-Pistofidis; Lorenzo Trippa; Yoshinobu Konishi; Omar Nadeem; Irene M. Ghobrial

Efficacy and safety of durcabtagene autoleucel in a phase 1 trial for patients with relapsed/refractory multiple myeloma 达鲁卡替ogene autoleucel在复发/难治性多发性骨髓瘤患者中的I期试验的疗效和安全性

Science Translational Medicine

IF14.6

2026-05-27

PREAI

Adam S. Sperling; Benjamin A. Derman; Sarah Nikiforow; Alejandro Alonso; Shuntaro Ikegawa; Nina Orwitz; David S. Quinn; David Pearson; Dexiu Bu; Pedro Milanez-Almeida; Jennifer Mataraza; Omar Nadeem; Jessica Liegel; Anita D’Souza; Allison Charles; Marc Credi; Jerome Ritz; Andrzej J. Jakubowiak; Serena De Vita; Nikhil C. Munshi

Ciltacabtagene autoleucel in high-risk smoldering multiple myeloma: the CAR-PRISM phase 2 trial Ciltacabtagene autoleucel在高风险冒烟型多发性骨髓瘤中的应用：CAR-PRISM二期临床试验

Nature Medicine

IF50

2026-04-20

OAAI

Omar Nadeem; David M. Cordas dos Santos; Sarah Nikiforow; Anna Bosch-Vilaseca; Elizabeth O’Donnell; Robert Redd; Kevin C. DeBraganca; Adam S. Sperling; Yuxin Liu; Caleb McEntire; Frances Arters; Colin O’Donnell; Brendan Kineavy; Marjorie Marto; Amy Bergeron; Emilie Swenson; Kristin McHugh; Abigail Caron; Quentin Berry; Hope Wei; Emily Durlacher; Elizabeth Grimm; Francesco Corrado; Nayda Bidikian; Rocio Montes de Oca; Tamar Lengil; Denise De Wiest; Casey Gervais; Kevin Panaro; Eric L. Smith; Kenneth Anderson; Caron Jacobson; Nikhil C. Munshi; Paul Richardson; Deepu Madduri; Jordan M. Schecter; Craig Tendler; Mark A. Wildgust; Lorenzo Trippa; Maria Victoria Mateos; Jerome Ritz; Irene M. Ghobrial

Preferred standard-of-care carfilzomib dosing in multiple myeloma: An international survey of haematologists/oncologists 多发性骨髓瘤中首选标准护理卡非佐米的剂量：血液学家/肿瘤学家的国际调查

British Journal of Haematology

IF3.8

2026-03-01

PREAI

Banerjee, Rahul; Dong, Sharlene; McCaughan, Georgia; Mehra, Nikita; Wang, Bo; Sperling, Adam S.; Cowan, Andrew J.; Anderson, Larry D.; Rajkumar, S. Vincent; Kaur, Gurbakhash

Putative multiple myeloma susceptibility genes identified by exome sequencing of 347 familial and early-onset cases 通过全外显子测序鉴定的347例家族性和早发性多发性骨髓瘤易感基因

Leukemia

IF13.4

2025-11-18

PREAI

Maroulio Pertesi; Delphine Demangel; Abhishek Niroula; Emeline Perrial; Maria Laura Mahecha Escobar; Maxime Vallée; Christine Liacos; Mehmet K. Samur; Adam S. Sperling; Nikhil C. Munshi; Efstathios Kastritis; Meletios A. Dimopoulos; James D. McKay; Ulf-Henrik Mellqvist; Markus Hansson; Charles Dumontet; Björn Nilsson

Mezigdomide for multiple myeloma: a focus on phase 2 trial data 美齐格多姆ide用于多发性骨髓瘤：重点关注II期试验数据

Expert Opinion on Emerging Drugs

IF2.7

2025-10-30

PREAI

Clifton C. Mo; Yuxin Liu; Omar Nadeem; Shonali Midha; Jacob P. Laubach; Taya Jamal Salman; Taylor Nicholson; Kaleigh Donnelly; Giada Bianchi; Adam S. Sperling; Monique A. Hartley-Brown; Paul G. Richardson

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation 扩展可成药的锌指蛋白质组界定了药物诱导降解的特性

Molecular Cell

IF16.6

2025-08-21

OAAI

Mikołaj Słabicki; Jiho Park; Radosław P. Nowak; Shourya S. Roy Burman; Jesse Pellman; Charles Zou; Hlib Razumkov; Jeannie Carreiro; Simran Rastogi; Anna Goldstein; Marek M. Nagiec; Katherine A. Donovan; Jianwei Che; Moritz Hunkeler; Qixiang Geng; Chi-Lin Hsu; Megha Lakshminarayan; Chelsea Shu; Rebecca L. Zon; Zuzanna Kozicka; Paul M.C. Park; Jonathan M. Tsai; Hojong Yoon; Lyn H. Jones; Adam S. Sperling; Nathanael S. Gray; Eric S. Fischer; Benjamin L. Ebert

Two clones, one niche: how CH shapes the MM microenvironment 两个克隆，一个生态位：CH如何塑造MM微环境

Blood

IF23.1

2025-07-31

PREAI

Adam S. Sperling

Invasive Fungal Disease is Rare in Relapsed/Refractory Multiple Myeloma Patients Treated with BCMA CAR T-cell Therapy 侵袭性真菌疾病在经BCMA CAR T细胞治疗的复发/难治性多发性骨髓瘤患者中较为罕见。

Blood Advances

IF7.1

2025-06-27

OAAI

Jessica S. Little; Angelica Medina Pena; E. Bridget Kim; Andrew J. Yee; Omar Nadeem; Shonali Midha; Adam S. Sperling; Nikhil C. Munshi; Noopur Raje; Matthew J. Frigault; Diana D. Cirstea; Sarah P. Hammond

Bridging intensity is associated with impaired hematopoietic recovery after BCMA CAR-T therapy for multiple myeloma 桥接强度与多发性骨髓瘤患者接受BCMA CAR-T疗法后的造血恢复受损相关

Blood Advances

IF7.1

2025-04-25

OAAI

Jan H. Frenking; Xiang Zhou; Kai Rejeski; Vivien Wagner; Patrick Costello; Thomas Hielscher; Lilan Gatti; Joseph Kauer; Omar Nadeem; Elias K. Mai; Christian S. Michel; Mirco J. Friedrich; David Sedloev; Niels Weinhold; Hartmut Goldschmidt; Klaus Herfarth; Anita Schmitt; Michael Hundemer; Michael Schmitt; Carsten Müller-Tidow; Max Topp; Hermann Einsele; Peter Dreger; Nikhil C. Munshi; Adam S. Sperling; Leo Rasche; Sandra Sauer; Marc S. Raab

Identification of small molecule inhibitors of PPM1D using an integrated drug discovery platform 使用集成药物发现平台鉴定PPM1D小分子抑制剂

ISCIENCE

IF4.1

2025-02-01

OAAI

Shaw, Subrata; Jiang, Wei; Rush, Jason; Dumont, Nancy; Kim, John; Singh, Ritu; Skepner, Adam; Khodier, Carol; Raffier, Cerise; Murphy, Zachary; Yan, Ni; Schluter, Cameron; Yu, Xiao; Szuchnicki, Mateusz; Sathappa, Murugappan; Kahn, Josephine; Sperling, Adam S.; Wagner, Florence; Mckinney, David C.; Gould, Alexandra E.; Garvie, Colin W.; Miller, Peter G.

Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-ChargeTM Platform 抗BCMA CAR-T Durcabtagene Autoleucel (PHE885) 的持久存在和功能活性：使用T-Charge™平台制备

BLOOD

IF23.1

2024-11-05

PREAI

Ikegawa, Shuntaro; Sperling, Adam S.; Nikiforow, Sarah; Ghazi, Andrew; Christidis, Anthony; Quinn, David; Bu, Dexiu; Mataraza, Jennifer; Pearson, David; Charles, Allison; Credi, Marc; Orwitz, Nina; Strange, Madisyn; Tamada, Rakuyo; Panaro, Kevin M.; Gervais, Casey; Ansuinelli, Michela; Arihara, Yohei; Prabhala, Rao; Reynolds, Carol G.; Gentleman, Robert; De Vita, Serena; Munshi, Nikhil C.; Ritz, Jerome

Long-term persistent exposure to cigarette smoke induces AhR driven corneal endothelial dysfunction in mice

EXPERIMENTAL EYE RESEARCH

IF2.7

2024-11-01

PREAI

Parekh, Mohit; Adhikari, Yadav; Deshpande, Neha; Miller, Peter; Sperling, Adam S.; Tesfaigzi, Yohannes; Jurkunas, Ula V.

Cytopenias in BCMA CAR T: unraveling inflammatory mechanisms

BLOOD ADVANCES

IF7.1

2024-10-24

OAAI

Sperling, Adam S.

EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma EASIX指导的复发/难治性多发性骨髓瘤中使用ide-cel进行CAR T细胞治疗后并发症和结局的风险分层

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2024-10-07

OAAI

Frenking, Jan H.; Zhou, Xiang; Wagner, Vivien; Hielscher, Thomas; Kauer, Joseph; Mai, Elias K.; Friedrich, Mirco J.; Michel, Christian S.; Hajiyianni, Marina; Breitkreutz, Iris; Costello, Patrick; Nadeem, Omar; Weinhold, Niels; Goldschmidt, Hartmut; Schmitt, Anita; Luft, Thomas; Schmitt, Michael; Mueller-Tidow, Carsten; Topp, Max; Einsele, Hermann; Dreger, Peter; Munshi, Nikhil C.; Sperling, Adam S.; Rasche, Leo; Sauer, Sandra; Raab, Marc S.

Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma 关于多发性骨髓瘤先兆临床试验优化设计的圆桌讨论

BLOOD CANCER DISCOVERY

IF11.5

2024-05-01

OAAI

Ghobrial, Irene M.; Gormley, Nicole; Kumar, Shaji K.; Mateos, Maria-Victoria; Bergsagel, P. Leif; Chesi, Marta; Dhodapkar, Madhav V.; Dispenzieri, Angela; Fonseca, Rafael; Getz, Gad; Kastritis, Efstathios; Kristinsson, Sigurdur Y.; Martinez-Climent, Jose Angel; Manier, Salomon; Marinac, Catherine R.; Maura, Francesco; Morgan, Gareth J.; Davies, Faith E.; Nadeem, Omar; Nuvolone, Mario; Paiva, Bruno; O'Donnell, Elizabeth; Prosper, Felipe; Shah, Urvi A.; Sklavenitis-Pistofidis, Romanos; Sperling, Adam S.; Vassiliou, George S.; Munshi, Nikhil C.; Castle, Philip E.; Anderson, Kenneth C.; San Miguel, Jesus F.

SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation (vol 30, pg 1503, 2023)

CELL STEM CELL

IF20.4

2024-02-01

OAAI

Chen, Chun-Wei; Zhang, Linda; Dutta, Ravi; Niroula, Abhishek; Miller, Peter G.; Gibson, Christopher J.; Bick, Alexander G.; Reyes, Jaime M.; Lee, Yi -Tang; Tovy, Ayala; Gu, Tianpeng; Waldvogel, Sarah; Chen, Yi-Hung; Venters, Bryan J.; Esteve, Pierre -Olivier; Pradhan, Sriharsa; Keogh, Michael-Christopher; Natarajan, Pradeep; Takahashi, Koichi; Sperling, Adam S.; Goodell, Margaret A.

Acute Lymphoblastic Leukemia with Myeloid Mutations Is a High-Risk Disease Associated with Clonal Hematopoiesis

BLOOD CANCER DISCOVERY

IF11.5

2023-12-26

OAAI

Saygin, Caner; Zhang, Pu; Stauber, Jacob; Aldoss, Ibrahim; Sperling, Adam S.; Weeks, Lachelle D.; Luskin, Marlise R.; Knepper, Todd C.; Wanjari, Pankhuri; Wang, Peng; Lager, Angela M.; Fitzpatrick, Carrie; Segal, Jeremy P.; Gharghabi, Mehdi; Gurbuxani, Sandeep; Venkataraman, Girish; Cheng, Jason X.; Eisfelder, Bart J.; Bohorquez, Oliver; Patel, Anand A.; Umesh Nagalakshmi, Sheethal; Jayaram, Savita; Odenike, Olatoyosi M.; Larson, Richard A.; Godley, Lucy A.; Arber, Daniel A.; Gibson, Christopher J.; Munshi, Nikhil C.; Marcucci, Guido; Ebert, Benjamin L.; Greally, John M.; Steidl, Ulrich; Lapalombella, Rosa; Shah, Bijal D.; Stock, Wendy

A safety review of recently approved and emerging drugs for patients with relapsed or refractory multiple myeloma 近期批准和新兴药物治疗复发或难治性多发性骨髓瘤的安全性评价

EXPERT OPINION ON DRUG SAFETY

IF3.1

2023-11-10

PREAI

Midha, Shonali; Hartley-Brown, Monique A.; Mo, Clifton C.; Hossain, Shahrier; Nadeem, Omar; O'Donnell, Elizabeth K.; Bianchi, Giada; Sperling, Adam S.; Laubach, Jacob P.; Richardson, Paul G.

研究方向