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P

Peter G. Miller

broad institute
H指数:33
被引数:4,862

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OGFOD1 enables AML chemo- and nutrient stress resistance by regulating protein synthesis

OGFOD1通过调控蛋白质合成使急性髓系白血病（AML）具有化疗和营养应激抗性。

Cell Metabolism
IF30.9
2025-09-160
PRE
Christina Mayerhofer; Dan Li; Trine Kristiansen; Ernst Mayerhofer; Azeem Sharda; Giulia Schiroli; Karin Gustafsson; Lingli He; Michael Mazzola; Sam Keyes; Anna Kiem; Eve Crompton; Yanxin Xu; Sovannarith Korm; Zhixun Dou; Charles Vidoudez; Peter G. Miller; Nick van Gastel; Timothy A. Graubert; David T. Scadden
Identification of small molecule inhibitors of PPM1D using an integrated drug discovery platform

使用集成药物发现平台鉴定PPM1D小分子抑制剂

ISCIENCE
IF4.1
2025-02-010
OAAI
Shaw, Subrata; Jiang, Wei; Rush, Jason; Dumont, Nancy; Kim, John; Singh, Ritu; Skepner, Adam; Khodier, Carol; Raffier, Cerise; Murphy, Zachary; Yan, Ni; Schluter, Cameron; Yu, Xiao; Szuchnicki, Mateusz; Sathappa, Murugappan; Kahn, Josephine; Sperling, Adam S.; Wagner, Florence; Mckinney, David C.; Gould, Alexandra E.; Garvie, Colin W.; Miller, Peter G.
Modulating mRNA Translation Fidelity As a Novel Mechanism for AML Chemoresistance

调节mRNA翻译保真度作为一种AML化疗耐药的新机制

BLOOD
IF23.1
2024-11-050
PRE
Mayerhofer, Christina; Li, Dan; Kristiansen, Trine A.; Mayerhofer, Ernst; Sharda, Azeem; He, Lingli; Mazzola, Michael; Schiroli, Giulia; Gustafsson, Karin; Keyes, Sam; Kiem, Anna; Crompton, Eve; Xu, Yanxin; Dou, Zhixun; Vidoudez, Charles; Miller, Peter G.; Van Gastel, Nick; Scadden, David
Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2024-10-231
PRE
Caldwell, Nicola; Peet, Caroline; Miller, Peter; Colon, Beatrice L.; Taylor, Malcolm G.; Cocco, Mattia; Dawson, Alice; Lukac, Iva; Teixeira, Jose E.; Robinson, Lee; Frame, Laura; Seizova, Simona; Damerow, Sebastian; Tamaki, Fabio; Post, John; Riley, Jennifer; Mutter, Nicole; Hanna, Jack C.; Ferguson, Liam; Hu, Xiao; Tinti, Michele; Forte, Barbara; Norcross, Neil R.; Campbell, Peter S.; Svensen, Nina; Caldwell, Flora C.; Jansen, Chimed; Postis, Vincent; Read, Kevin D.; Huston, Christopher D.; Gilbert, Ian H.; Baragana, Beatriz; Pawlowic, Mattie C.
SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation (vol 30, pg 1503, 2023)
CELL STEM CELL
IF20.4
2024-02-010
OA
Chen, Chun-Wei; Zhang, Linda; Dutta, Ravi; Niroula, Abhishek; Miller, Peter G.; Gibson, Christopher J.; Bick, Alexander G.; Reyes, Jaime M.; Lee, Yi -Tang; Tovy, Ayala; Gu, Tianpeng; Waldvogel, Sarah; Chen, Yi-Hung; Venters, Bryan J.; Esteve, Pierre -Olivier; Pradhan, Sriharsa; Keogh, Michael-Christopher; Natarajan, Pradeep; Takahashi, Koichi; Sperling, Adam S.; Goodell, Margaret A.
Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
2023-12-015
PRE
Yun, Jeong H.; Khan, M. A. Wasay; Ghosh, Auyon; Hobbs, Brian D.; Castaldi, Peter J.; Hersh, Craig P.; Miller, Peter G.; Cool, Carlyne D.; Sciurba, Frank; Barwick, Lucas; Limper, Andrew H.; Flaherty, Kevin; Criner, Gerard J.; Brown, Kevin; Wise, Robert; Martinez, Fernando; Silverman, Edwin K.; DeMeo, Dawn; Cho, Michael H.; Bick, Alexander G.
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability
MOLECULAR CELL
IF16.6
2023-08-0121
OAAI
Tsai, Jonathan M.; Aguirre, Jacob D.; Li, Yen-Der; Brown, Jared; Focht, Vivian; Kater, Lukas; Kempf, Georg; Sandoval, Brittany; Schmitt, Stefan; Rutter, Justine C.; Galli, Pius; Sandate, Colby R.; Cutler, Jevon A.; Zou, Charles; Donovan, Katherine A.; Lumpkin, Ryan J.; Cavadini, Simone; Park, Paul M. C.; Sievers, Quinlan; Hatton, Charlie; Ener, Elizabeth; Regalado, Brandon D.; Sperling, Micah T.; Sabicki, Mikoaj; Kim, Jeonghyeon; Zon, Rebecca; Zhang, Zinan; Miller, Peter G.; Belizaire, Roger; Sperling, Adam S.; Fischer, Eric S.; Irizarry, Rafael; Armstrong, Scott A.; Thoma, Nicolas H.; Ebert, Benjamin L.
Clonal hematopoiesis in older patients with breast cancer receiving chemotherapy
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
2023-04-126
OA
Mayerhofer, Christina; Sedrak, Mina S.; Hopkins, Judith O.; Li, Tianyu; Tayob, Nabihah; Faggen, Meredith G.; Sinclair, Natalie F.; Chen, Wendy Y.; Parsons, Heather A.; Mayer, Erica L.; Lange, Paulina B.; Basta, Ameer S.; Perilla-Glen, Adriana; Lederman, Ruth, I; Wong, Andrew R.; Tiwari, Abhay; McAllister, Sandra S.; Mittendorf, Elizabeth A.; Gibson, Christopher J.; Burstein, Harold J.; Kim, Annette S.; Freedman, Rachel A.; Miller, Peter G.
Clonal hematopoiesis of indeterminate potential after (neo)adjuvant chemotherapy versus endocrine therapy for early breast cancer: the CIRCE-eBC prospective cohort study
CANCER RESEARCH
IF16.6
2023-03-010
PRE
Morganti, Stefania; Jin, Qingchun; Santos, Katheryn; Gibson, Christopher; Patel, Ashka; Wilson, Alex; Merrill, Margaret; Vincuilla, Julie; Stokes, Samantha; Lipsyc-Sharf, Marla; Parker, Tonia; King, Tari; Mittendorf, Elizabeth A.; Curigliano, Giuseppe; Hughes, Melissa E.; Tayob, Nabihah; Lin, Nancy U.; Miller, Peter; Tolaney, Sara; Garber, Judy; Parsons, Heather A.
Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2022-08-1526
OAAI
Sellar, Rob S.; Sperling, Adam S.; Slabicki, Mikolaj; Gasser, Jessica A.; McConkey, Marie E.; Donovan, Katherine A.; Mageed, Nada; Adams, Dylan N.; Zou, Charles; Miller, Peter G.; Dutta, Ravi K.; Boettcher, Steffen; Lin, Amy E.; Sandoval, Brittany; Barrios, Vanessa A. Quevedo; Kovalcik, Veronica; Koeppel, Jonas; Henderson, Elizabeth K.; Fink, Emma C.; Yang, Lu; Chan, Anthony; Pokharel, Sheela Pangeni; Bergstrom, Erik J.; Burt, Rajan; Udeshi, Namrata D.; Carr, Steven A.; Fischer, Eric S.; Chen, Chun-Wei; Ebert, Benjamin L.
Allosteric inhibition of PPM1D serine/threonine phosphatase via an altered conformational state
NATURE COMMUNICATIONS
IF15.7
2022-06-3017
OAAI
Miller, Peter G.; Sathappa, Murugappan; Moroco, Jamie A.; Jiang, Wei; Qian, Yue; Iqbal, Sumaiya; Guo, Qi; Giacomelli, Andrew O.; Shaw, Subrata; Vernier, Camille; Bajrami, Besnik; Yang, Xiaoping; Raffier, Cerise; Sperling, Adam S.; Gibson, Christopher J.; Kahn, Josephine; Jin, Cyrus; Ranaghan, Matthew; Caliman, Alisha; Brousseau, Merissa; Fischer, Eric S.; Lintner, Robert; Piccioni, Federica; Campbell, Arthur J.; Root, David E.; Garvie, Colin W.; Ebert, Benjamin L.
PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

PPM1D突变是从头弥漫性中线胶质瘤形成的致癌驱动因素

NATURE COMMUNICATIONS
IF15.7
2022-02-0127
OAAI
Khadka, Prasidda; Reitman, Zachary J.; Lu, Sophie; Buchan, Graham; Gionet, Gabrielle; Dubois, Frank; Carvalho, Diana M.; Shih, Juliann; Zhang, Shu; Greenwald, Noah F.; Zack, Travis; Shapira, Ofer; Pelton, Kristine; Hartley, Rachel; Bear, Heather; Georgis, Yohanna; Jarmale, Spandana; Melanson, Randy; Bonanno, Kevin; Schoolcraft, Kathleen; Miller, Peter G.; Condurat, Alexandra L.; Gonzalez, Elizabeth M.; Qian, Kenin; Morin, Eric; Langhnoja, Jaldeep; Lupien, Leslie E.; Rendo, Veronica; Digiacomo, Jeromy; Wang, Dayle; Zhou, Kevin; Kumbhani, Rushil; Garcia, Maria E. Guerra; Sinai, Claire E.; Becker, Sarah; Schneider, Rachel; Vogelzang, Jayne; Krug, Karsten; Goodale, Amy; Abid, Tanaz; Kalani, Zohra; Piccioni, Federica; Beroukhim, Rameen; Persky, Nicole S.; Root, David E.; Carcaboso, Angel M.; Ebert, Benjamin L.; Fuller, Christine; Babur, Ozgun; Kieran, Mark W.; Jones, Chris; Keshishian, Hasmik; Ligon, Keith L.; Carr, Steven A.; Phoenix, Timothy N.; Bandopadhayay, Pratiti

研究方向

暂未获取到该数据
B
Benjamin L. Ebert
H 指数:122论文数:775被引数:15.4万
C
Christopher D. Huston
H 指数:34论文数:104被引数:5,283
E
Erin E. Stebbins
H 指数:11论文数:29被引数:533
C
Christopher J. Gibson
H 指数:44论文数:263被引数:1.2万
A
Adam S. Sperling
H 指数:34论文数:331被引数:5,975
J
José E. Teixeira
H 指数:8论文数:38被引数:237
M
Marvin J. Meyers
H 指数:32论文数:99被引数:3,892
R
Rajiv S. Jumani
H 指数:14论文数:26被引数:908
D
David T. Scadden
H 指数:124论文数:667被引数:6.7万
M
Melissa S. Love
H 指数:15论文数:29被引数:1,132