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A

Arkady Khoutorsky

mcgill university
H指数:36
被引数:5,301

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Microglia regulate neuronal activity via structural remodeling of astrocytes

小胶质细胞通过星形胶质细胞的形态重塑来调节神经元活动。

Neuron
IF15
2025-08-190
PRE
Ning Gu; Olena Makashova; Celeste Laporte; Chris Qilongyue Chen; Banruo Li; Pierre-Marie Chevillard; Graham Lean; Jieyi Yang; Calvin Wong; Jonathan Fan; Behrang Sharif; Susana Puche Saud; Misha Hubacek; Katrina Y. Choe; Margaret M. McCarthy; Arkady Khoutorsky; Charles W. Bourque; Masha Prager-Khoutorsky
mRNA translation in astrocytes controls hippocampal long- term synaptic plasticity and memory

星形胶质细胞的mRNA翻译控制海马长时程突触可塑性和记忆

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-11-283
OAAI
Sharma, Vijendra; Oliveira, Mauricio M.; Sood, Rapita; Khlaifia, Abdessattar; Lou, Danning; Hooshmandi, Mehdi; Hung, Tzu-Yu; Mahmood, Niaz; Reeves, Maya; Ho-Tieng, David; Cohen, Noah; Cheng, Po-chieh; Rahim, Mir Munir A.; Prager-Khoutorsky, Masha; Kaufman, Randal J.; Rosenblum, Kobi; Lacaille, Jean- Claude; Khoutorsky, Arkady; Klann, Eric; Sonenberg, Nahum
4E-BP1-dependent translation in nociceptors controls mechanical hypersensitivity via TRIM32/type I interferon signaling

伤害感受器中的4e-bp1依赖性翻译通过TRIM32/I型干扰素信号控制机械超敏反应

SCIENCE ADVANCES
IF12.5
2023-11-033
OAAI
Wong, Calvin; Tavares-Ferreira, Diana; Perez, Carolina Thorn; Sharif, Behrang; Uttam, Sonali; Amiri, Mehdi; Lister, Kevin C.; Hooshmandi, Mehdi; Nguyen, Vivienne; Seguela, Philippe; Sonenberg, Nahum; Price, Theodore J.; Gkogkas, Christos G.; Khoutorsky, Arkady
Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome
NEURON
IF15
2023-10-016
PRE
Hooshmandi, Mehdi; Sharma, Vijendra; Perez, Carolina Thorn; Sood, Rapita; Krimbacher, Konstanze; Wong, Calvin; Lister, Kevin C.; Guzman, Alba Urena; Bartley, Trevor D.; Rocha, Cecilia; Maussion, Gilles; Nadler, Emma; Roque, Patricia Margarita; Gantois, Ilse; Popic, Jelena; Levesque, Maxime; Kaufman, Randal J.; Avoli, Massimo; Sanz, Elisenda; Nader, Karim; Hagerman, Randi Jenssen; Durcan, Thomas M.; Costa-Mattioli, Mauro; Prager-Khoutorsky, Masha; Lacaille, Jean-Claude; Martinez-Cerdeno, Veronica; Gibson, Jay R.; Huber, Kimberly M.; Sonenberg, Nahum; Gkogkas, Christos G.; Khoutorsky, Arkady
Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice

小白蛋白中间神经元丢失介导小鼠反复麻醉诱导的记忆缺陷

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-01-1710
OAAI
Roque, Patricia Soriano; Perez, Carolina Thorn; Hooshmandi, Mehdi; Wong, Calvin; Eslamizade, Mohammad Javad; Heshmati, Shilan; Brown, Nicole; Sharma, Vijendra; Lister, Kevin C.; Goyon, Vanessa Magalie; Neagu-Lund, Laura; Shen, Cathy; Daccache, Nicolas; Sato, Hiroaki; Sato, Tamaki; Mogil, Jeffrey S.; Nader, Karim; Gkogkas, Christos G.; Iordanova, Mihaela D.; Prager-Khoutorsky, Masha; McBride, Heidi M.; Lacaille, Jean-Claude; Wykes, Linda; Schricker, Thomas; Khoutorsky, Arkady
Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1

Mnk1/2激酶通过Syngap1调节记忆和自闭症相关行为

BRAIN
IF11.7
2022-10-314
OA
Chalkiadaki, Kleanthi; Hooshmandi, Mehdi; Lach, Gilliard; Statoulla, Elpida; Simbriger, Konstanze; Amorim, Ines S.; Kouloulia, Stella; Zafeiri, Maria; Pothos, Panagiotis; Bonneil, Eric; Gantois, Ilse; Popic, Jelena; Kim, Sung-Hoon; Wong, Calvin; Cao, Ruifeng; Komiyama, Noboru H.; Atlasi, Yaser; Jafarnejad, Seyed Mehdi; Khoutorsky, Arkady; Gkogkas, Christos G.
The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related 1 (LARP1)
JOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
2022-09-018
OAAI
Farooq, Zeenat; Kusuma, Fedho; Burke, Phillip; Dufour, Catherine R.; Lee, Duckgue; Tabatabaei, Negar; Toboz, Phoenix; Radovani, Ernest; Greenblatt, Jack F.; Rehman, Jalees; Class, Jacob; Khoutorsky, Arkady; Fonseca, Bruno D.; Richner, Justin M.; Mercier, Eloi; Bourque, Guillaume; Giguere, Vincent; Subramaniam, Arvind R.; Han, Jaeseok; Tahmasebi, Soroush
The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-08-227
OAAI
Toboz, Phoenix; Amiri, Mehdi; Tabatabaei, Negar; Dufour, Catherine R.; Kim, Seung Hyeon; Fillebeen, Carine; Ayemoba, Charles E.; Khoutorsky, Arkady; Nairz, Manfred; Shao, Lijian; Pajcini, Kostandin V.; Kim, Ki-Wook; Giguere, Vincent; Oliveira, Regiana L.; Constante, Marco; Santos, Manuela M.; Morales, Carlos R.; Pantopoulos, Kostas; Sonenberg, Nahum; Pinho, Sandra; Tahmasebi, Soroush
mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2022-08-0115
OAAI
Wong, Calvin; Barkai, Omer; Wang, Feng; Perez, Carolina Thorn; Lev, Shaya; Cai, Weihua; Tansley, Shannon; Yousefpour, Noosha; Hooshmandi, Mehdi; Lister, Kevin C.; Latif, Mariam; Cuello, A. Claudio; Prager-Khoutorsky, Masha; Mogil, Jeffrey S.; Seguela, Philippe; De Koninck, Yves; Ribeiro-da-Silva, Alfredo; Binshtok, Alexander M.; Khoutorsky, Arkady
Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
NATURE COMMUNICATIONS
IF15.7
2022-02-1172
OAAI
Tansley, Shannon; Uttam, Sonali; Guzman, Alba Urena; Yaqubi, Moein; Pacis, Alain; Parisien, Marc; Deamond, Haley; Wong, Calvin; Rabau, Oded; Brown, Nicole; Haglund, Lisbet; Ouellet, Jean; Santaguida, Carlo; Ribeiro-da-Silva, Alfredo; Tahmasebi, Soroush; Prager-Khoutorsky, Masha; Ragoussis, Jiannis; Zhang, Ji; Salter, Michael W.; Diatchenko, Luda; Healy, Luke M.; Mogil, Jeffrey S.; Khoutorsky, Arkady
Microglia-mediated degradation of perineuronal nets promotes pain

小胶质细胞介导的神经周神经网降解促进疼痛

Science
IF45.8
2022-01-010
OA
Shannon N. Tansley; Ning Gu; Alba Ureña Guzmán; Weihua Cai; Calvin Wong; Kevin C. Lister; Einer Muñoz-Pino; Noosha Yousefpour; Robert Brian Roome; Jordyn Heal; Neil Wu; Annie Castonguay; Graham Lean; Elizabeth M. Muir; Artur Kania; Masha Prager‐Khoutorsky; Ji Zhang; Christos G. Gkogkas; James W. Fawcett; Luda B. Diatchenko; Alfredo Ribeiro‐da‐Silva; Yves De Koninck; Jeffrey S. Mogil; Arkady Khoutorsky
Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1
SCIENTIFIC REPORTS
IF3.9
2021-07-297
OAAI
Roque, Patricia Soriano; Hooshmandi, Mehdi; Neagu-Lund, Laura; Yin, Shelly; Yousefpour, Noosha; Sato, Hiroaki; Sato, Tamaki; Nakadate, Yosuke; Kawakami, Akiko; Tahmasebi, Soroush; Ribeiro-da-Silva, Alfredo; Gkogkas, Christos G.; Prager-Khoutorsky, Masha; Schricker, Thomas; Wykes, Linda; Khoutorsky, Arkady

研究方向

暂未获取到该数据
N
Nahum Sonenberg
H 指数:178论文数:959被引数:12.4万
C
Christos G. Gkogkas
H 指数:30论文数:92被引数:4,183
M
Masha Prager‐Khoutorsky
H 指数:24论文数:56被引数:2,355
C
Calvin Wong
H 指数:13论文数:33被引数:757
M
Mehdi Hooshmandi
H 指数:13论文数:30被引数:300
J
Jeffrey S. Mogil
H 指数:96论文数:359被引数:4.0万
S
Soroush Tahmasebi
H 指数:19论文数:40被引数:1,719
J
Jean‐Claude Lacaille
H 指数:61论文数:172被引数:1.2万
S
Seyed Mehdi Jafarnejad
H 指数:30论文数:88被引数:3,110
A
Alfredo Ribeiro‐da‐Silva
H 指数:52论文数:184被引数:8,057