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A

Andrew J. Innes

imperial college london
H指数:27
被引数:3,904

个人简介

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教育背景

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工作经历

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荣誉奖项

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Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid leukaemia
Nature Communications
IF15.7
2026-07-280
OA
Alessandro Donada; Gurvan Hermange; Tiziana Tocci; Adil Midoun; Giulio Prevedello; Louisa Hadj Abed; Délia Dupré; Wenjie Sun; Idan Milo; Sabrina Tenreira Bento; Constandina Pospori; Andrew J. Innes; Christophe Willekens; Jacques Vargaftig; David Michonneau; Cristina Lo Celso; Nicolas Servant; Ken R. Duffy; Hervé Isambert; Paul-Henry Cournède; Lucie Laplane; Leïla Perié
Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer

剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications
IF15.7
2026-04-150
OAAI
Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil
Phase 2 study of the lysine-specific demethylase 1 (LSD1) inhibitor bomedemstat for essential thrombocythemia

LSD1（赖氨酸特异性去甲基化酶1）抑制剂bomedemstat治疗原发性血小板增多症的2期研究

Blood Advances
IF7.1
2026-03-030
OAAI
Harinder Gill; Francesca Palandri; David M. Ross; Joachim R. Göthert; Tara Cochrane; Stephen R. Larsen; Anna B. Halpern; Jake Shortt; James M. Rossetti; James Liang; Monia Marchetti; Andrew J. Wilson; Andrew J. Innes; Merit Hanna; Nicola Vianelli; William S. Stevenson; Alessandro M. Vannucchi; Maria Kleppe; Jessica Flynn; Georges Natsoulis
BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs

BCR::ABL1诱导的增强子重编程揭示了Ph+B-ALL细胞对增强子靶向药物的异常敏感性

Advanced Science
IF14.1
2026-03-010
OAAI
Han Leng Ng; Trudy Lee Glaser; Jintao Zhu; Mark E. Robinson; Kadriye N. Cosgun; Valeriya Malysheva; Ozgen Deniz; Nicholas T. Crump; Kaiyue Helian; Andrew J. Innes; Richard Burt; Li Sun; George John; Haibin Zhou; Atsunori Kaneshige; Longchuan Bai; Shaomeng Wang; Mikhail Spivakov; Markus Mueschen; Niklas Feldhahn
Multiarm multistage randomised controlled trial of inflammatory signal inhibitors (MATIS) for patients hospitalised with COVID-19 pneumonia during the UK pandemic

针对疫情期间因COVID-19肺炎住院患者的炎症信号抑制剂多臂多阶段随机对照试验（MATIS）

BMJ Open
IF2.3
2026-02-010
PRE
Hazell, Lorna; Pillay, Clio; Cornelius, Victoria; Phillips, Rachel; Charania, Asad; Wason, James; Cherlin, Svetlana; Savic, Sinisa; Whittington, Ashley; Neelakantan, Pratap; Collini, Paul; Cook, Lucy; Willicome, Michelle; Milojkovic, Dragana; Kon, Onn Min; Youngstein, Taryn; Innes, Andrew; Thursz, Mark; Cooke, Graham S.; Vergis, Nikhil; Cooper, Nichola
Investigation and management of thrombocytosis without JAK2, CALR or MPL mutations: A British Society for Haematology Guideline

无JAK2、CALR或MPL突变性血小板增多症的检查与管理：英国血液学标准化委员会指南

BRITISH JOURNAL OF HAEMATOLOGY
IF3.8
2025-12-010
OAAI
Godfrey, Anna L.; Khan, Alesia A.; McGregor, Andrew; Innes, Andrew J.; Altohami, Mohammed; Cross, Nicholas C. P.; Frewin, Rebecca; Garg, Mamta; Green, Anna; Grinfeld, Jacob; McLornan, Donal P.; Wilson, Andrew J.; Harrison, Claire N.; Mead, Adam J.; Nangalia, Jyoti
Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia

靶向凋亡的BH3拟似物：改变急性髓系白血病患者的治疗方法

Nature Reviews Clinical Oncology
IF82.2
2025-09-010
PRE
Antonino Glaviano; Ellen Weisberg; Hiu Y. Lam; Donavan J. J. Tan; Andrew J. Innes; Yubin Ge; Catherine E. Lai; Wendy Stock; Christina Glytsou; Linda Smit; Tatsushi Yoshida; Tian Y. Zhang; Vanessa E. Kennedy; B. Douglas Smith; Thomas Mercher; Stéphane de Botton; Patrizia Diana; Marina Konopleva; Michael J. Mauro; James D. Griffin; Courtney D. DiNardo; Alan P. Kumar
Thrombocytosis and Bleeding in Myeloproliferative Neoplasms: Exploring Clinical Diversity and risk of acquired Von Willebrand Syndrome – Insights from a UK Centre

骨髓增殖性肿瘤中的血小板增多症和出血：探讨临床多样性与获得性范科布兰德综合征的风险——来自英国中心的研究见解

Research and Practice in Thrombosis and Haemostasis
IF3.4
2025-06-010
OAAI
Giulia Simini; Andrew Innes; Saravanan Vinayagam; Golzar Mobayen; Nilanthi Karawitage; Simone Claudiani; Zain Odho; Mike Laffan; Deepa J. Arachchillage
B-Precursor Acute Lymphoblastic Leukaemia Causes Paracrine Senescence in Mesenchymal Stromal Cells to Subvert the Treatment Response in Adult Acute Lymphoblastic Leukaemia

B-Precursor 急性淋巴细胞白血病通过诱导间充质基质细胞发生旁分泌性衰老来颠覆成人急性淋巴细胞白血病的治疗反应

BLOOD
IF23.1
2024-11-050
PRE
Dey, Aditi; Kumari, Ruchi; Innes, Andrew J.; Cutler, Emily A.; Allen, Hermione E.; Chatzigerou, Jenny; Amerikanou, Rodothea; Ward, Juma; Gil, Jesus; Fielding, Adele Kay; Kirschner, Kristina
Real World Efficacy and Safety of Momelotinib for Myelofibrosis: Evaluation of a UK-Wide Study Confirms 40% Anaemia Response Rate in a Non-Clinical Trial Cohort

真实世界中Momelotinib治疗骨髓纤维化的疗效与安全性：一项英国全国性研究的评估证实了在非临床试验队列中40%的贫血缓解率

BLOOD
IF23.1
2024-11-052
PRE
Rampotas, Alexandros; Torre, Elena; Carter-Brzezinski, Luke; Duminuco, Andrea; Cadman-Davies, Llywelyn; Chee, Ashlyn; Panitsas, Fotios; Alimam, Samah; Milojkovic, Dragana; Kaczmarski, Richard; Fraser, Louise; Frewin, Rebecca; Foley, Kate; Hockings, Catherine; Khan, Alesia; Williams, Rhys; Ryan, Jennifer; Yip, Kawai; Thaw, Kyaw Htin; Sheikh, Amna; Wadelin, Frances; Godfrey, Anna L.; Teh, Chun Huat; Wilson, Andrew J.; Lambert, Jonathan; Mead, Adam J.; Mclornan, Donal P.; Innes, Andrew J.; Mcgregor, Andrew; Somervaille, Tim; Harrison, Claire; Harrington, Patrick; Psaila, Bethan
Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST): A Multi-Center Randomized Double-Blinded Placebo-Controlled Phase IIa Trial

肠道微生物群移植在异基因干细胞移植（MAST）之前：一项多中心随机双盲安慰剂对照IIa期试验

BLOOD
IF23.1
2024-11-050
PRE
Mullish, Benjamin H.; Innes, Andrew J.; Ghani, Rohma; Anim-Burton, Shian; Webber, Lee; Wheeler, Graham; Johnson, Nicholas A.; Roberts, Lauren; Davies, Frances J.; Marchesi, Julian R.; Pavlu, Jiri
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
LEUKEMIA
IF13.4
2024-09-170
OAAI
Innes, Andrew J.; Hayden, Chloe; Orovboni, Victoria; Claudiani, Simone; Fernando, Fiona; Khan, Afzal; Rees, David; Byrne, Jennifer; Gallipoli, Paolo; Francis, Sebastian; Copland, Mhairi; Horne, Gillian; Raghavan, Manoj; Arnold, Claire; Collins, Angela; Cranfield, Tanya; Cunningham, Nicholas; Danga, Akila; Forsyth, Peter; Frewin, Rebecca; Garland, Paula; Hannah, Guy; Avenoso, Daniele; Hassan, Sandra; Huntly, Brian J. P.; Husain, Jissan; Makkuni, Sudhakaran; Rothwell, Kate; Khorashad, Jamshid; Apperley, Jane F.; Milojkovic, Dragana
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype (vol 17, pg 1205, 2015)

mTOR调节MAPKAPK2翻译以控制衰老相关的分泌表型 (vol 17，pg 1205，2015)

NATURE CELL BIOLOGY
IF19.1
2024-05-221
OA
Herranz, Nicolas; Gallage, Suchira; Mellone, Massimiliano; Wuestefeld, Torsten; Klotz, Sabrina; Hanley, Christopher J.; Raguz, Selina; Acosta, Juan Carlos; Innes, Andrew J.; Banito, Ana; Georgilis, Athena; Montoya, Alex; Wolter, Katharina; Dharmalingam, Gopuraja; Faull, Peter; Carroll, Thomas; Martinez-Barbera, Juan Pedro; Cutillas, Pedro; Reisinger, Florian; Heikenwalder, Mathias; Miller, Richard A.; Withers, Dominic; Zender, Lars; Thomas, Gareth J.; Gil, Jesus

研究方向

暂未获取到该数据
D
Dragana Milojković
H 指数:46论文数:301被引数:1.0万
S
Simone Claudiani
H 指数:12论文数:68被引数:504
J
Jane F. Apperley
H 指数:109论文数:809被引数:5.1万
F
Fiona Fernando
H 指数:8论文数:32被引数:137
A
Afzal Khan
H 指数:33论文数:151被引数:2,810
J
Jiří Pavlů
H 指数:23论文数:144被引数:2,930
J
Jesús Gil
H 指数:72论文数:232被引数:2.9万
J
Juan Pedro Martı́nez-Barberá
H 指数:59论文数:227被引数:1.2万
S
Suchira Gallage
H 指数:18论文数:49被引数:2,854
E
Eduardo Olavarría
H 指数:56论文数:303被引数:1.1万