Jesús Gil - Publications, H-index & Citations

Jesús Gil

imperial college london

72H指数

229论文数

2.9W被引数

收录论文 109

发表时间

Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability 亲电化合物筛选鉴定出GPX4依赖性铁死亡为衰老的易损性

Nature Cell Biology

IF19.1

2026-04-24

OAAI

Mariantonietta D’Ambrosio; Matthew E. H. White; Efthymios S. Gavriil; Laura Bousset; Jodie Birch; Aleksandra Gruevska; Emiliano Pasquini; Manuel Colucci; Winnie Fong; Simone Mosole; Aurora Valdata; Dimitris Veroutis; Katie Tyson; Vikas Ranvir; Sandra Prokosch; Joaquim Pombo; Aoki Ardisson; Sanjay Khadayate; George Young; Alex Montoya; Georgia Roumelioti; Jack Houghton; Jianan Lu; Pavel V. Shliaha; Elena De Vita; Santiago Vernia; Vassilis G. Gorgoulis; Suchira Gallage; Mathias Heikenwälder; Zoe Hall; Andrea Alimonti; Iain A. McNeish; Edward W. Tate; Jesús Gil

Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer 剪接体诱导是RAS驱动的衰老和癌症的药物依赖性

Nature Communications

IF15.7

2026-04-15

OAAI

Verena Wagner; Laura Bousset; Mariana Ascensão-Ferreira; Bin Sun; José Efren Barragan Avila; Alexandre Kaizeler; Rita Martins-Silva; Mohammad Rahbari; Mirian Fernández-Vaquero; Scott Haston; Michele Tinti; Joaquim Pombo; Sanjay Khadayate; Susanne Roth; Christian M. Schürch; Juan Pedro Martínez-Barbera; Anat Bahat; Keng Boon Wee; Jennifer P. Morton; Nisar Malek; Andrew J. Innes; Santiago Vernia; Nuno L. Barbosa-Morais; Suchira Gallage; Mathias Heikenwalder; Jesús Gil

High-Throughput Proteomics Sample Preparation Using a 96-Channel Pipettor and Magnetic Pin Device 使用96通道移液器和磁力针装置的高通量蛋白质组学样品制备

Journal of Proteome Research

IF3.6

2026-02-01

PREAI

Roumelioti, Georgia; Montoya, Alex; Fisher, Gemma L. M.; Navarro, Eneko Pascual; Woods, Angela; Bennett, Jane; Navaratnam, Naveenan; Gonzalez-Carvajal, Oliver; Birch, Jodie; Pyman, Elizabeth; Yu, Sijia; Gruevska, Aleksandra; Vuillemenot, Luc-Alban; Lushchak, Oleh; Hall, Zoe; Barr, Alexis R.; Speck, Christian; Vernia, Santiago; Scott, William R.; Gil, Jesus; Aragon, Luis; Fets, Louise; Carling, David; Shliaha, Pavel V.

TERT expression attenuates metabolic disorders in obese mice by promoting adipose stem and progenitor cell expansion and differentiation TERT表达通过促进脂肪干细胞和祖细胞的增殖与分化，缓解肥胖小鼠的代谢紊乱。

Molecular Metabolism

IF6.6

2025-10-03

OAAI

Laura Braud; Manuel Bernabe; Julien Vernerey; Antonio M.A. Miranda; Andrea Dominguez; Dmitri Churikov; Manon Richaud; Frédéric Jourquin; Liam Mc Allan; Christophe Lachaud; Jesus Gil; Will Scott; Vincent Géli

Senescence as a therapeutic target in cancer and age-related diseases 衰老作为癌症和年龄相关疾病的治疗靶点

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2024-11-15

PREAI

McHugh, Domhnall; Duran, Imanol; Gil, Jesus

B-Precursor Acute Lymphoblastic Leukaemia Causes Paracrine Senescence in Mesenchymal Stromal Cells to Subvert the Treatment Response in Adult Acute Lymphoblastic Leukaemia B-Precursor 急性淋巴细胞白血病通过诱导间充质基质细胞发生旁分泌性衰老来颠覆成人急性淋巴细胞白血病的治疗反应

BLOOD

IF23.1

2024-11-05

PREAI

Dey, Aditi; Kumari, Ruchi; Innes, Andrew J.; Cutler, Emily A.; Allen, Hermione E.; Chatzigerou, Jenny; Amerikanou, Rodothea; Ward, Juma; Gil, Jesus; Fielding, Adele Kay; Kirschner, Kristina

Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome 核糖体S6激酶1通过衰老分泌组调节炎症

NATURE AGING

IF19.4

2024-08-29

OAAI

Gallage, Suchira; Irvine, Elaine E.; Barragan Avila, Jose Efren; Reen, Virinder; Pedroni, Silvia M. A.; Duran, Imanol; Ranvir, Vikas; Khadayate, Sanjay; Pombo, Joaquim; Brookes, Sharon; Heide, Danijela; Dharmalingham, Gopuraja; Choudhury, Agharul I.; Singh, Indrabahadur; Herranz, Nicolas; Vernia, Santiago; Heikenwalder, Mathias; Gil, Jesus; Withers, Dominic J.

The promise of machine learning approaches to capture cellular senescence heterogeneity 机器学习方法捕捉细胞衰老异质性的前景

NATURE AGING

IF19.4

2024-08-26

PREAI

Duran, Imanol; Bishop, Cleo L.; Gil, Jesus; Wallis, Ryan

mTOR links nutrients, inflammaging and lifespan mTOR链接营养，发炎和寿命

NATURE AGING

IF19.4

2024-07-26

PREAI

Cocheme, Helena M.; Gil, Jesus

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype (vol 17, pg 1205, 2015)mTOR调节MAPKAPK2翻译以控制衰老相关的分泌表型 (vol 17，pg 1205，2015)

NATURE CELL BIOLOGY

IF19.1

2024-05-22

OAAI

Herranz, Nicolas; Gallage, Suchira; Mellone, Massimiliano; Wuestefeld, Torsten; Klotz, Sabrina; Hanley, Christopher J.; Raguz, Selina; Acosta, Juan Carlos; Innes, Andrew J.; Banito, Ana; Georgilis, Athena; Montoya, Alex; Wolter, Katharina; Dharmalingam, Gopuraja; Faull, Peter; Carroll, Thomas; Martinez-Barbera, Juan Pedro; Cutillas, Pedro; Reisinger, Florian; Heikenwalder, Mathias; Miller, Richard A.; Withers, Dominic; Zender, Lars; Thomas, Gareth J.; Gil, Jesus

Detection of senescence using machine learning algorithms based on nuclear features 基于核特征的机器学习算法在衰老检测中的应用

NATURE COMMUNICATIONS

IF15.7

2024-02-03

OAAI

Duran, Imanol; Pombo, Joaquim; Sun, Bin; Gallage, Suchira; Kudo, Hiromi; Mchugh, Domhnall; Bousset, Laura; Barragan Avila, Jose Efren; Forlano, Roberta; Manousou, Pinelopi; Heikenwalder, Mathias; Withers, Dominic J.; Vernia, Santiago; Goldin, Robert D.; Gil, Jesus

COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells COPI囊泡形成和N-肉豆蔻酰化是衰老细胞的可靶向脆弱性

NATURE CELL BIOLOGY

IF19.1

2023-11-27

OAAI

McHugh, Domhnall; Sun, Bin; Gutierrez-Munoz, Carmen; Hernandez-Gonzalez, Fernanda; Mellone, Massimiliano; Guiho, Romain; Duran, Imanol; Pombo, Joaquim; Pietrocola, Federico; Birch, Jodie; Kallemeijn, Wouter W.; Khadayate, Sanjay; Dharmalingam, Gopuraja; Vernia, Santiago; Tate, Edward W.; Martinez-Barbera, Juan Pedro; Withers, Dominic J.; Thomas, Gareth J.; Serrano, Manuel; Gil, Jesus

The challenge of identifying senescent cells 识别衰老细胞的挑战

NATURE CELL BIOLOGY

IF19.1

2023-10-26

PREAI

Gil, Jesus

Proteome-wide structural analysis identifies warhead- and coverage-specific biases in cysteine-focused chemoproteomics 蛋白质组范围的结构分析确定了以半胱氨酸为重点的化学蛋白质组学中弹头和覆盖特异性偏差

CELL CHEMICAL BIOLOGY

IF7.2

2023-07-01

OAAI

White, Matthew E. H.; Gil, Jesus; Tate, Edward W.

Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies 通过细胞衰老重塑肿瘤微环境: 衰老疗法的机会

DEVELOPMENTAL CELL

IF8.7

2023-06-01

OAAI

DAmbrosio, Mariantonietta; Gil, Jesus

Spurious transcription may be a hallmark of aging 虚假转录可能是衰老的标志

NATURE AGING

IF19.4

2023-03-30

OAAI

Isima, Nikita; Gil, Jesus

TRAF family proteins link PKR with NF-κB activation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

158

OAAI

Gil, J; García, MA; Gomez-Puertas, P; Guerra, S; Rullas, J; Nakano, H; Alcamí, J; Esteban, M

Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

531

OAAI

Bernstein, E; Duncan, EM; Masui, O; Gil, J; Heard, E; Allis, CD

Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression 消除衰老细胞可促进肺动脉高压的发生和发展

CIRCULATION

IF38.6

2023-02-21

OAAI

Born, Emmanuelle; Lipskaia, Larissa; Breau, Marielle; Houssaini, Amal; Beaulieu, Delphine; Marcos, Elisabeth; Pierre, Remi; Do Cruzeiro, Marcio; Lefevre, Marine; Derumeaux, Genevieve; Bulavin, Dmitry V.; Delcroix, Marion; Quarck, Rozenn; Reen, Virinder; Gil, Jesus; Bernard, David; Flaman, Jean-Michel; Adnot, Serge; Abid, Shariq

RETRACTION: CBX7 controls the growth of normal and tumor-derived prostate cells by repressing the Ink4a/Arf locus (Retraction of Vol 24, Pg 5543, 2005)回缩: CBX7通过抑制Ink4a/Arf基因座来控制正常和肿瘤来源的前列腺细胞的生长 (第24卷，5543页，2005页)

ONCOGENE

IF7.3

2022-10-17

OAAI

Bernard, David; Martinez-Leal, Juan F.; Rizzo, Sian; Martinez, Dolores; Hudson, David; Visakorpi, Tapio; Peters, Gordon; Carnero, Amancio; Beach, David; Gil, Jesus

研究方向