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Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer 微卫星稳定型结直肠癌中DNA突变率的异质性与进化 Grassi, Elena; Vurchio, Valentina; Cresswell, George D.; Catalano, Irene; Lupo, Barbara; Sassi, Francesco; Galimi, Francesco; Borgato, Sofia; Ferri, Martina; Viviani, Marco; Pompei, Simone; Urgese, Gianvito; Chen, Bingjie; Zanella, Eugenia R.; Cottino, Francesca; Russo, Mariangela; Mauri, Gianluca; Pietrantonio, Filippo; Zampino, Maria Giulia; Lazzari, Luca; Marsoni, Silvia; Bardelli, Alberto; Lagomarsino, Marco Cosentino; Sottoriva, Andrea; Trusolino, Livio 分享 收藏
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer (Vol 56, pg 458, 2024) Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; McCooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D. 分享 收藏
Molecular and therapeutic characterization of a large-scale collection of metastatic colorectal cancer patient-derived xenografts and matched organoids for translational oncology Leto, Simonetta M.; Grassi, Elena; Avolio, Marco; Vurchio, Valentina; Cottino, Francesca; Ferri, Martina; Zanella, Eugenia R.; Di Blasio, Laura; Puliafito, Alberto; Primo, Luca; Bertotti, Andrea; Trusolino, Livio 分享 收藏
Unravelling intra-tumor phenotypic heterogeneity in colorectal cancer organoids Fletcher, Sabrina J.; Catalano, Irene; Grassi, Elena; Borgato, Sofia; Peracino, Barbara; Piretto, Elena; Alessandri, Luca; Calogero, Raffaele; Primo, Luca; Trusolino, Livio; Bertotti, Andrea; Puliafito, Alberto 分享 收藏
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer Malla, Sudhir B.; Byrne, Ryan M.; Lafarge, Maxime W.; Corry, Shania M.; Fisher, Natalie C.; Tsantoulis, Petros K.; Mills, Megan L.; Ridgway, Rachel A.; Lannagan, Tamsin R. M.; Najumudeen, Arafath K.; Gilroy, Kathryn L.; Amirkhah, Raheleh; Maguire, Sarah L.; Mulholland, Eoghan J.; Belnoue-Davis, Hayley L.; Grassi, Elena; Viviani, Marco; Rogan, Emily; Redmond, Keara L.; Sakhnevych, Svetlana; Mccooey, Aoife J.; Bull, Courtney; Hoey, Emily; Sinevici, Nicoleta; Hall, Holly; Ahmaderaghi, Baharak; Domingo, Enric; Blake, Andrew; Richman, Susan D.; Isella, Claudio; Miller, Crispin; Bertotti, Andrea; Trusolino, Livio; Loughrey, Maurice B.; Kerr, Emma M.; Tejpar, Sabine; Maughan, Timothy S.; Lawler, Mark; Campbell, Andrew D.; Leedham, Simon J.; Koelzer, Viktor H.; Sansom, Owen J.; Dunne, Philip D. 分享 收藏
Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer Beekhof, Robin; Bertotti, Andrea; Boettger, Franziska; Vurchio, Valentina; Cottino, Francesca; Zanella, Eugenia R.; Migliardi, Giorgia; Viviani, Marco; Grassi, Elena; Lupo, Barbara; Henneman, Alex A.; Knol, Jaco C.; Pham, Thang V.; de Goeij-de Haas, Richard; Piersma, Sander R.; Labots, Mariette; Verheul, Henk M. W.; Trusolino, Livio; Jimenez, Connie R. 分享 收藏
MSI cancer associated DNA (TA)n-dinucleotide repeat expansions and implications for Werner synthetic lethality Picco, Gabriele; Bhosle, Shriram; Kalyva, Maria; Grassi, Elena; Gibson, Freddy; Al Saedi, Angham; Vieira, Sara; Sanders, Mathijs; Trusolino, Livio; Bertotti, Andrea; Mathew, Isidro Cortes-Ciriano 分享 收藏
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT) Falcinelli, Marta; Dell'Omo, Giulia; Grassi, Elena; Mariella, Elisa; Leto, Simonetta Maria; Scardellato, Sharon; Lorenzato, Annalisa; Arena, Sabrina; Bertotti, Andrea; Trusolino, Livio; Bardelli, Alberto; di Fagagna, Fabrizio d'Adda 分享 收藏
Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer Leto, Simonetta M.; Ferri, Martina; Sassi, Francesco; Zanella, Eugenia R.; Cottino, Francesca; Vurchio, Valentina; Catalano, Irene; Ferrero, Alessandro; Zingaretti, Caterina C.; Marchio, Caterina; Grassi, Elena; Trusolino, Livio; Bertotti, Andrea 分享 收藏
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Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin Tedesco, Martina; Giannese, Francesca; Lazarevic, Dejan; Giansanti, Valentina; Rosano, Dalia; Monzanis, Silvia; Catalano, Irene; Grassi, Elena; Zanella, Eugenia R.; Botrugno, Oronza A.; Morelli, Leonardo; Bordignon, Paola Panina; Caravagna, Giulio; Bertotti, Andrea; Martino, Gianvito; Aldrighetti, Luca; Pasqualato, Sebastiano; Trusolino, Livio; Cittaro, Davide; Tonon, Giovanni 分享 收藏
ESDN inhibits melanoma progression by blocking E-selectin expression in endothelial cells via STAT3 Coppo, Roberto; Orso, Francesca; Virga, Federico; Dalmasso, Alberto; Baruffaldi, Desiree; Nie, Lei; Clapero, Fabiana; Dettori, Daniela; Quirico, Lorena; Grassi, Elena; Defilippi, Paola; Provero, Paolo; Valdembri, Donatella; Serini, Guido; Sadeghi, Mehran M.; Mazzone, Massimiliano; Taverna, Daniela 分享 收藏
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype Lupo, Barbara; Sassi, Francesco; Pinnelli, Marika; Galimi, Francesco; Zanella, Eugenia R.; Vurchio, Valentina; Migliardi, Giorgia; Gagliardi, Paolo Armando; Puliafito, Alberto; Manganaro, Daria; Luraghi, Paolo; Kragh, Michael; Pedersen, Mikkel W.; Horak, Ivan D.; Boccaccio, Carla; Medico, Enzo; Primo, Luca; Nichol, Daniel; Spiteri, Inmaculada; Heide, Timon; Vatsiou, Alexandra; Graham, Trevor A.; Elez, Elena; Argiles, Guillem; Nuciforo, Paolo; Sottoriva, Andrea; Dienstmann, Rodrigo; Pasini, Diego; Grassi, Elena; Isella, Claudio; Bertotti, Andrea; Trusolino, Livio 分享 收藏
Pertuzumab and trastuzumab emtansine in patients with HER2-amplified metastatic colrectal cancer: the phase II HERACLES-B trial Sartore-Bianchi, Andrea; Lonardi, Sara; Martino, Cosimo; Fenocchio, Elisabetta; Tosi, Federica; Ghezzi, Silvia; Leone, Francesco; Bergamo, Francesca; Zagonel, Vittorina; Ciardiello, Fortunato; Ardizzoni, Andrea; Amatu, Alessio; Bencardino, Katia; Valtorta, Emanuele; Grassi, Elena; Torri, Valter; Bonoldi, Emanuela; Sapino, Anna; Vanzulli, Angelo; Regge, Daniele; Cappello, Giovanni; Bardelli, Alberto; Trusolino, Livio; Marsoni, Silvia; Siena, Salvatore 分享 收藏
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Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors 由RNA结合蛋白Elavl3介导的替代性聚腺苷酸化位点的选择在抑制性神经元祖细胞的分化中起作用 Grassi, Elena; Santoro, Roberto; Umbach, Alessandro; Grosso, Anna; Oliviero, Salvatore; Neri, Francesco; Conti, Luciano; Ala, Ugo; Provero, Paolo; DiCunto, Ferdinando; Merlo, Giorgio R. 分享 收藏
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