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FANCM is required for the PAX3::FOXO1-driven oncogenic program in rhabdomyosarcoma FANCM在横纹肌肉瘤中对于PAX3::FOXO1驱动的癌基因程序是必需的 Delaney, Christopher D.; Lu, Min; Zimmerman, Seth P.; Meng, Yingying; Vaganay, Camille; Cerda-Smith, Christian G.; Liu, Annie; Hoj, Jacob P.; Killarney, Shane T.; Dillon, Kerry; Stewart, Amy E.; Huang, Kevin; Caci, Julia D.; White, Olivia; Puissant, Alexandre; Root, David E.; Shern, Jack F.; Eyler, Christine E.; Chen, Chun-Wei David; Counter, Christopher M.; Linardic, Corinne M.; Zou, Lee; Wood, Kris C. 分享 收藏
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SMARCAL1 is a targetable synthetic lethal therapeutic vulnerability in ATRX-deficient gliomas that use alternative lengthening of telomeres SMARCAL1是ATRX缺陷型胶质瘤中一种可靶向的合成致死治疗弱点,该胶质瘤使用端粒替代性延长机制 Brown, Alexandrea; Strickland, Laura M.; Erman, Elise N.; Pirozzi, Christopher J.; Low, Justin T.; Diplas, Bill H.; Gibson, Emiley; Shobande, Mariah; Khambati, Taher; Krylova, Marharyta; Liu, Heng; Mclendon, Roger E.; Reitman, Zachary J.; Keir, Stephen T.; Zou, Lee; Ashley, David M.; Waitkus, Matthew S. 分享 收藏
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A RAD18-UBC13-PALB2-RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells Cybulla, Emily; Wallace, Sierra; Meroni, Alice; Jackson, Jessica; Agashe, Sumedha; Tennakoon, Mithila; Limbu, Mangsi; Quinet, Annabel; Lomonosova, Elena; Noia, Hollie; Tirman, Stephanie; Wood, Matthew; Lemacon, Delphine; Fuh, Katherine; Zou, Lee; Vindigni, Alessandro 分享 收藏
Unprocessed genomic uracil as a source of DNA replication stress in cancer cells Saxena, Sneha; Nabel, Christopher S.; Seay, Turner W.; Patel, Parasvi S.; Kawale, Ajinkya S.; Crosby, Caroline R.; Tigro, Helene; Oh, Eugene; Vander Heiden, Matthew G.; Hata, Aaron N.; Suo, Zucai; Zou, Lee 分享 收藏
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair (vol 15, 1568, 2024) Wang, Yumin; Gao, Boya; Zhang, Luyuan; Wang, Xudong; Zhu, Xiaolan; Yang, Haibo; Zhang, Fengqi; Zhu, Xueping; Zhou, Badi; Yao, Sean; Nagayama, Aiko; Lee, Sanghoon; Ouyang, Jian; Koh, Siang-Boon; Eisenhauer, Eric L.; Zarrella, Dominique; Lu, Kate; Rueda, Bo R.; Zou, Lee; Su, Xiaofeng A.; Yeku, Oladapo; Ellisen, Leif W.; Wang, Xiao-Song; Lan, Li 分享 收藏
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair 减数分裂蛋白SYCP2通过R环介导的DNA修复赋予对DNA损伤剂的抗性 Wang, Yumin; Gao, Boya; Zhang, Luyuan; Wang, Xudong; Zhu, Xiaolan; Yang, Haibo; Zhang, Fengqi; Zhu, Xueping; Zhou, Badi; Yao, Sean; Nagayama, Aiko; Lee, Sanghoon; Ouyang, Jian; Koh, Siang-Boon; Eisenhauer, Eric L.; Zarrella, Dominique; Lu, Kate; Rueda, Bo R.; Zou, Lee; Su, Xiaofeng A.; Yeku, Oladapo; Ellisen, Leif W.; Wang, Xiao-Song; Lan, Li 分享 收藏
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An ATR-PrimPol pathway confers tolerance to oncogenic KRAS-induced and heterochromatin-associated replication stress Atr-primpol途径赋予对致癌KRAS诱导和异染色质相关复制应激的耐受性 Igarashi, Taichi; Mazevet, Marianne; Yasuhara, Takaaki; Yano, Kimiyoshi; Mochizuki, Akifumi; Nishino, Makoto; Yoshida, Tatsuya; Yoshida, Yukihiro; Takamatsu, Nobuhiko; Yoshimi, Akihide; Shiraishi, Kouya; Horinouchi, Hidehito; Kohno, Takashi; Hamamoto, Ryuji; Adachi, Jun; Zou, Lee; Shiotani, Bunsyo 分享 收藏
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