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Titia de Lange

Rockefeller University

106H指数
244论文数
5.2W被引数
收录论文 77
发表时间
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How telomere attrition protects against cancer端粒缩短如何保护机体免受癌症侵害
errNature Reviews Genetics
IF52
err2026-09-01
err0
PREAI
errAlexander Stuart; Bokai Zhang; Dirk Hockemeyer; Titia de Lange
err分享
err收藏
Attenuation of ATM signaling by ROS delays replicative senescence at physiological oxygenROS对ATM信号的衰减延迟了生理氧条件下的复制性衰老
errMolecular Cell
IF16.6
err2025-12-01
err0
PREAI
errAlexander J. Stuart; Kaori K. Takai; Railia R. Gabbasova; Henry Sanford; Ekaterina V. Vinogradova; Titia de Lange
err分享
err收藏
DNA-PK controls Apollo's access to leading-end telomeres
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-02-26
err5
errOAAI
errSonmez, Ceylan; Toia, Beatrice; Eickhoff, Patrik; Matei, Andreea Medeea; El Beyrouthy, Michael; Wallner, Bjoern; Douglas, Max E.; de Lange, Titia; Lottersberger, Francisca
err分享
err收藏
Most large structural variants in cancer genomes can be detected without long reads
errNATURE GENETICS
IF31.8
err2023-11-09
err9
errOAAI
errChoo, Zi-Ning; Behr, Julie M.; Deshpande, Aditya; Hadi, Kevin; Yao, Xiaotong; Tian, Huasong; Takai, Kaori; Zakusilo, George; Rosiene, Joel; Paula, Arnaud Da Cruz; Weigelt, Britta; Setton, Jeremy; Riaz, Nadeem; Powell, Simon N.; Busam, Klaus; Shoushtari, Alexander N.; Ariyan, Charlotte; Reis-Filho, Jorge; de Lange, Titia; Imielinski, Marcin
err分享
err收藏
DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-08-31
err11
errOAAI
errMyler, Logan R.; Toia, Beatrice; Vaughan, Cara K.; Takai, Kaori; Matei, Andreea M.; Wu, Peng; Paull, Tanya T.; de Lange, Titia; Lottersberger, Francisca
err分享
err收藏
Control of human telomere length by TRF1 and TRF2
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err765
errOAAI
errSmogorzewska, A; Van Steensel, B; Bianchi, A; Oelmann, S; Schaefer, MR; Schnapp, G; De Lange, T
err分享
err收藏
Targeted deletion reveals an essential function for the telomere length regulator Trf1
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err166
errOAAI
errKarlseder, J; Kachatrian, L; Takai, H; Mercer, M; Hingorani, S; Jacks, T; de Lange, T
err分享
err收藏
No overt nucleosome eviction at deprotected telomeres
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err37
errOAAI
errWu, Peng; de Lange, Titia
err分享
err收藏
Functional Dissection of Human and Mouse POT1 Proteins
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err124
errOAAI
errPalm, Wilhelm; Hockemeyer, Dirk; Kibe, Tatsuya; de Lange, Titia
err分享
err收藏
Cell Cycle-Dependent Role of MRN at Dysfunctional Telomeres: ATM Signaling-Dependent Induction of Nonhomologous End Joining (NHEJ) in G1 and Resection-Mediated Inhibition of NHEJ in G2
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err105
errOAAI
errDimitrova, Nadya; de Lange, Titia
err分享
err收藏
TRF2-Tethered TIN2 Can Mediate Telomere Protection by TPP1/POT1
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err69
errOAAI
errFrescas, David; de lange, Titia
err分享
err收藏
Telomere Protection by TPP1 Is Mediated by POT1a and POT1b
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err121
errOAAI
errKibe, Tatsuya; Osawa, Gail A.; Keegan, Catherine E.; de Lange, Titia
err分享
err收藏
CST/Polα/primase-mediated fill-in synthesis at DSBs
errCELL CYCLE
IF3.4
err2022-10-07
err7
errOAAI
errMirman, Zachary; Cai, Sarah; de Lange, Titia
err分享
err收藏
Shelterin is a dimeric complex with extensive structural heterogeneity
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-07-26
err22
errOAAI
errZinder, John C.; Olinares, Paul Dominic B.; Svetlov, Vladimir; Bush, Martin W.; Nudler, Evgeny; Chait, Brian T.; Walz, Thomas; De lange, Titia
err分享
err收藏
Cryo-EM structure of the human CST-Polα/primase complex in a recruitment state
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2022-05-16
err40
errOAAI
errCai, Sarah W.; Zinder, John C.; Svetlov, Vladimir; Bush, Martin W.; Nudler, Evgeny; Walz, Thomas; de Lange, Titia
err分享
err收藏
Expression of BRCA1, BRCA2, RAD51, and other DSB repair factors is regulated by CRL4WDR70
errDNA REPAIR
IF2.7
err2022-05-01
err6
errOAAI
errMirman, Zachary; Sharma, Keshav; Carroll, Thomas S.; de Lange, Titia
err分享
err收藏
53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesisBRCA1-deficient细胞中的53bp1-依赖于屏蔽蛋白的DSB加工需要cst-polα-primase补全合成
errNATURE CELL BIOLOGY
IF19.1
err2022-01-13
err32
errOAAI
errMirman, Zachary; Sasi, Nanda Kumar; King, Ashleigh; Chapman, J. Ross; de Lange, Titia
err分享
err收藏
Structural variant evolution after telomere crisis端粒危机后的结构变异演变
errNATURE COMMUNICATIONS
IF15.7
err2021-04-07
err14
errOAAI
errDewhurst, Sally M.; Yao, Xiaotong; Rosiene, Joel; Tian, Huasong; Behr, Julie; Bosco, Nazario; Takai, Kaori K.; de Lange, Titia; Imielinski, Marcin
err分享
err收藏
TINF2 is a haploinsufficient tumor suppressor that limits telomere length
errELIFE
IF0
err2020-12-01
err39
errOAAI
errSchmutz, Isabelle; Mensenkamp, Arjen R.; Takai, Kaori K.; Haadsma, Maaike; Spruijt, Liesbeth; de Voer, Richarda M.; Choo, Seunga Sara; Lorbeer, Franziska K.; van Grinsven, Emma J.; Hockemeyer, Dirk; Jongmans, Marjolijn C. J.; de Lange, Titia
err分享
err收藏
APOBEC3-dependent kataegis and TREX1-driven chromothripsis during telomere crisis端粒危机期间的APOBEC3-dependent kataegis和TREX1-driven色素病
errNATURE GENETICS
IF31.8
err2020-07-27
err104
errOAAI
errMaciejowski, John; Chatzipli, Aikaterini; Dananberg, Alexandra; Chu, Kevan; Toufektchan, Eleonore; Klimczak, Leszek J.; Gordenin, Dmitry A.; Campbell, Peter J.; de Lange, Titia
err分享
err收藏

研究方向

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合作学者
合作期刊
B
Bert Vogelstein
H 指数: 255 · 论文数: 1.0K
M
Matthias Mann
H 指数: 250 · 论文数: 1.4K
K
Kenneth W. Kinzler
H 指数: 213 · 论文数: 785
M
Michel C. Nussenzweig
H 指数: 183 · 论文数: 618
P
Peter J. Campbell
H 指数: 159 · 论文数: 747
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