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T

Ton N. Schumacher

Netherlands Cancer Institute
H指数:109
被引数:8.3万

个人简介

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荣誉奖项

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Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition in metastatic TNBC

肿瘤微环境的时空组成可预测转移性TNBC对免疫检查点抑制的反应

Nature Cancer
IF28.5
2026-02-180
PRE
Noah F. Greenwald; Iris Nederlof; Cameron Sowers; Daisy Yi Ding; Seongyeol Park; Alex Kong; Kathleen E. Houlahan; Sricharan Reddy Varra; Manon de Graaf; Veerle Geurts; Candace C. Liu; Jolene S. Ranek; Leonie Voorwerk; Michiel de Maaker; Adam Kagel; Erin McCaffrey; Aziz Khan; Christine Yiwen Yeh; Christine Camacho Fullaway; Zumana Khair; Brennan G. Simon; Yunhao Bai; Hadeesha Piyadasa; Tyler Risom; Alea Delmastro; Felix J. Hartmann; Lise Mangiante; Cristina Sotomayor-Vivas; Sean C. Bendall; Ton N. Schumacher; Zhicheng Ma; Marc Bosse; Marc J. van de Vijver; Robert Tibshirani; Hugo M. Horlings; Christina Curtis; Marleen Kok; Michael Angelo
NEO-STIM advances personalized neoantigen-specific adoptive T cell therapy

Neo-stim推进个性化新抗原特异性过继性T细胞治疗

Nature Communications
IF15.7
2026-02-050
OAAI
Divya Lenkala; Jessica Kohler; Brian McCarthy; Michael Nelson; Noor A. M. Bakker; Renate de Boer; Emily K. Jackson; Joong Hyuk F. Sheen; Susan Hannes; Ekaterina Esaulova; Kai Stewart; Claudia Gottstein; John Attanasio; Flavian D. Brown; Sebastian Hymson; Shirisha Meda; Maaike van Zon; Saskia Scheij; Rhianne Voogd; Brenda Raud; Ziyan Xu; Jessica S. W. Borgers; Maartje W. Rohaan; Kristen N. Balogh; Asaf Poran; Michael Rooney; Jesse Z. Dong; John R. Srouji; Vikram R. Juneja; Christina M. Arieta; Cynthia M. Nijenhuis; Bastiaan Nuijen; Mark DeMario; Kelledy Manson; Ton N. M. Schumacher; Richard B. Gaynor; John B. Haanen; Joost H. van den Berg; Marit M. van Buuren
Guidelines for T cell nomenclature

T细胞命名指南

Nature Reviews Immunology
IF60.9
2025-11-180
OAAI
David Masopust; Amit Awasthi; Rémy Bosselut; David G. Brooks; Marcus Buggert; Kenji Chamoto; Weiguo Cui; Chen Dong; Donna L. Farber; Thomas Gebhardt; Carmen Gerlach; Ananda Goldrath; Philip D. Greenberg; J. Scott Hale; Adrian Hayday; Dirk Homann; Matteo Iannacone; Stephen C. Jameson; Marc K. Jenkins; Nikhil S. Joshi; Susan M. Kaech; Axel Kallies; Alice O. Kamphorst; Mark H. Kaplan; Paul Klenerman; Marco Künzli; Antonio Lanzavecchia; Georg M. Lauer; Enrico Lugli; Andrew D. Luster; Laura K. Mackay; M. Juliana McElrath; Scott N. Mueller; Zaza Ndhlovu; Thumbi Ndung’u; Pamela S. Ohashi; Annette Oxenius; Giuseppe Pantaleo; Marion Pepper; Louis J. Picker; Clare F. Quarnstrom; Gustavo Reyes-Terán; Mario Roederer; Pamela C. Rosato; Gonzalo Salgado-Montes de Oca; Federica Sallusto; Ton N. Schumacher; Daniella M. Schwartz; Eui-Cheol Shin; Andrew G. Soerens; Daniela S. Thommen; Vaiva Vezys; João P. B. Viola; Bruce D. Walker; Tania H. Watts; Casey T. Weaver; E. John Wherry; Hai-Hui Xue; Ben Youngblood; Rafi Ahmed
In Remembrance of Professor Zelig Eshhar: A Life Committed to CAR-T

缅怀泽利格·埃什哈教授：一位致力于CAR-T的一生

Human Gene Therapy
IF4
2025-11-010
PRE
Debets, Reno; Hawkins, Robert; Gilham, David; Gorochov, Guy; Schumacher, Ton; Uckert, Wolfgang; Blankenstein, Thomas; Crawford, Dorothy; Taylor, Naomi; Szollosi, Janos; Stauss, Hans; Mondino, Anna; Allavena, Paola; Alarcon, Balbino; Buning, Hildegard; Abken, Hinrich
Neoadjuvant immunotherapy in mismatch-repair-proficient colon cancers

错配修复功能 proficient 结直肠癌的新辅助免疫疗法

Nature
IF48.5
2025-10-200
PRE
Pedro B. Tan; Yara L. Verschoor; José G. van den Berg; Sara Balduzzi; Niels F. M. Kok; Marieke E. Ijsselsteijn; Kat Moore; Adham Jurdi; Antony Tin; Paulien Kaptein; Monique E. van Leerdam; John B. A. G. Haanen; Emile E. Voest; Noel F. C. C. de Miranda; Ton N. Schumacher; Lodewyk F. A. Wessels; Myriam Chalabi
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial

新辅助伊匹木单抗和纳武利尤单抗在可切除皮肤鳞状细胞癌中的应用：一项随机Ⅱ期临床试验

Nature Medicine
IF50
2025-10-080
OAAI
Sabine E. Breukers; Joleen J. H. Traets; Stan W. van Dijk; Mercedes Machuca Ostos; Itske Fraterman; Robert D. Crommelin; Hedda van der Hulst; Xiaohang Qiao; Thomas Boere; Lonneke V. van de Poll-Franse; Valesca Retèl; Vincent van der Noort; Joris L. Vos; Alexandra G. L. Toppenberg; Martijn van der Heijden; Francesco Missale; Fons Balm; Michiel van den Brekel; Richard Dirven; M. Baris Karakullukcu; Luc Karssemakers; W. Martin C. Klop; Peter J.F.M Lohuis; Willem H. Schreuder; Ludi E. Smeele; Lilly-Ann van der Velden; Elsemieke Plasmeijer; Laura A. Smit; Jan Paul de Boer; Arash Navran; Bram Westerink; Petra K. de Koekkoek-Doll; Jonas Castelijns; Maurits Wondergem; Wouter V. Vogel; Anke Kuijpers; Winan J. van Houdt; Suzanne Onderwater; Esther Maas-Bannink; Sten Cornelissen; Annegien Broeks; Bernard M. Tijink; Lot A. Devriese; Remco de Bree; Christian U. Blank; Ton N. Schumacher; Daniela S. Thommen; John B.A.G. Haanen; Charlotte L. Zuur
Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma

III期黑色素瘤患者尽管对术前ipiLimumab联合nivolumab治疗表现出病理学反应，但疾病仍复发时的临床、病理及分子特征

Communications Medicine
IF6.3
2025-09-300
OA
Judith M. Versluis; Huma Shehwana; Robert Elens; Alexander M. Menzies; Irene L. M. Reijers; Petros Dimitriadis; Nigel G. Maher; Astrid M. M. van der Veldt; Ellen Kapiteijn; Annegien Broeks; Richard A. Scolyer; Bart A. van de Wiel; Alexander C. J. van Akkooi; Ton N. Schumacher; Georgina V. Long; Christian U. Blank
Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies

基于从诊断性肿瘤活检样本高通量TCR发现，实现下一代工程化TCR-T疗法

NATURE COMMUNICATIONS
IF15.7
2025-01-140
OA
Kuilman, Thomas; Schrikkema, Deborah S.; Gadiot, Jules; Gomez-Eerland, Raquel; Bies, Laura; Walker, Julia; Spaapen, Robbert M.; Kok, Hanna; Houg, Demi; Viyacheva, Milena; Claassen, Yvonne B.; Saornil, Manuel; Krijgsman, Oscar; Stringer, Bas; Ding, Huiwen; Geleijnse, Anou; Meinema, Anne C.; Weissbrich, Bianca; Lancee, Melissa; Engele, Carmen G.; Sabatino, Marianna; Chen, Pei-Ling; Tsai, Kenneth Y.; Mule, James J.; Sondak, Vernon K.; van den Bulk, Jitske; de Miranda, Noel F.; Jedema, Inge; Haanen, John G.; van Heijst, Jeroen W. J.; Schumacher, Ton N.; Linnemann, Carsten; Bendle, Gavin M.
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial

新辅助nivolumab或nivolumab联合ipilimumab治疗早期三阴性乳腺癌: 2期适应性试验

NATURE MEDICINE
IF50
2024-09-162
OAAI
Nederlof, Iris; Isaeva, Olga I.; de Graaf, Manon; Gielen, Robbert C. A. M.; Bakker, Noor A. M.; Rolfes, Adrianne L.; Garner, Hannah; Boeckx, Bram; Traets, Joleen J. H.; Mandjes, Ingrid A. M.; de Maaker, Michiel; van Brussel, Thomas; Chelushkin, Maksim; Champanhet, Elisa; Lopez-Yurda, Marta; van de Vijver, Koen; van den Berg, Jose G.; Hofland, Ingrid; Klioueva, Natasja; Mann, Ritse M.; Loo, Claudette E.; van Duijnhoven, Frederieke H.; Skinner, Victoria; Luykx, Sylvia; Kerver, Emile; Kalashnikova, Ekaterina; van Dongen, Marloes G. J.; Sonke, Gabe S.; Linn, Sabine C.; Blank, Christian U.; de Visser, Karin E.; Salgado, Roberto; Wessels, Lodewyk F. A.; Drukker, Caroline A.; Schumacher, Ton N.; Horlings, Hugo M.; Lambrechts, Diether; Kok, Marleen
Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial
NATURE MEDICINE
IF50
2024-09-150
OAAI
de Gooyer, Peter G. M.; Verschoor, Yara L.; van den Dungen, Lauren D. W.; Balduzzi, Sara; Marsman, Hendrik A.; Foppen, Marnix H. Geukes; Grootscholten, Cecile; Dokter, Simone; den Hartog, Anne G.; Verbeek, Wieke H. M.; Woensdregt, Karlijn; van den Broek, Joris J.; Oosterling, Steven J.; Schumacher, Ton N.; Kuhlmann, Koert F. D.; Beets-Tan, Regina G. H.; Haanen, John B. A. G.; van Leerdam, Monique E.; van den Berg, Jose G.; Chalabi, Myriam
Neoadjuvant immunotherapy in locally advanced MMR-deficient colon cancer: 3-year disease-free survival from NICHE-2

局部晚期MMR-deficient结肠癌的新辅助免疫疗法：NICHE-2研究3年无病生存率

ANNALS OF ONCOLOGY
IF65.4
2024-09-013
PRE
Chalabi, M.; van den Dungen, L. D. W.; Verschoor, Y. L.; Balduzzi, S.; de Gooyer, P. G. M.; Kok, N.; Kerver, E.; Grootscholten, C.; Voest, E. E.; Burger, J. W. A.; Hendriks, E. R.; de Wijkerslooth, T. R.; Tin, T.; Aukema, T. S.; Oosterling, S. J.; Aalbers, A. G.; van den Berg, J. G.; van Leerdam, M. E.; Schumacher, T. N.; Haanen, J. B. A. G.
Neoadjuvant nivolumab/relatlimab or nivolumab/ ipilimumab in triple negative breast cancer with high tumor-infiltrating lymphocytes (TILs)

新辅助尼沃鲁单抗/瑞拉利单抗或尼沃鲁单抗/伊匹木单抗在肿瘤浸润淋巴细胞(TILs)较高的三阴性乳腺癌中的应用

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Nederlof, I.; Rolfes, A. L.; Gielen, R. C. A. M.; Awada, G.; Dongen, M. V.; Horlings, H. M.; Van De Vijver, K.; Drukker, C. A.; Van Duijnhoven, F.; Lopez-Yurda, M.; Mandjes, I.; Mann, R. M.; Loo, C. E.; Blank, C. U.; Schumacher, T. N.; Salgado, R. F.; Kok, M.
Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer
NEW ENGLAND JOURNAL OF MEDICINE
IF78.5
2024-06-0634
PRE
Chalabi, Myriam; Verschoor, Yara L.; Tan, Pedro Batista; Balduzzi, Sara; Van Lent, Anja U.; Grootscholten, Cecile; Dokter, Simone; Bueller, Nike V.; Grotenhuis, Brechtje A.; Kuhlmann, Koert; Burger, Jacobus W.; Huibregtse, Inge L.; Aukema, Tjeerd S.; Hendriks, Eduard R.; Oosterling, Steven J.; Snaebjornsson, Petur; Voest, Emile E.; Wessels, Lodewyk F.; Beets-Tan, Regina G.; Van Leerdam, Monique E.; Schumacher, Ton N.; van den Berg, Jose G.; Beets, Geerard L.; Haanen, John B.

研究方向

暂未获取到该数据
J
John B.A.G. Haanen
H 指数:109论文数:931被引数:9.7万
C
Christian U. Blank
H 指数:95论文数:670被引数:5.8万
M
Mireille Toebes
H 指数:34论文数:84被引数:7,141
C
Carsten Linnemann
H 指数:19论文数:54被引数:3,806
P
Pia Kvistborg
H 指数:39论文数:122被引数:1.7万
D
Daniela S. Thommen
H 指数:25论文数:206被引数:7,929
S
Sine Reker Hadrup
H 指数:49论文数:366被引数:1.2万
E
Emile E. Voest
H 指数:92论文数:810被引数:3.7万
K
Karolina Sikorska
H 指数:39论文数:191被引数:1.0万
G
Gavin Bendle
H 指数:19论文数:68被引数:2,206