John Sondek - Publications, H-index & Citations

John Sondek

University of North Carolina Chapel Hill

59H指数

210论文数

1.3W被引数

收录论文 61

发表时间

Optogenetic control of PLC-γ1 activity directs cell motility 光遗传学控制PLC-γ1活性指导细胞运动

Journal of Cell Biology

IF6.4

2026-05-05

PREAI

Appalabhotla, Ravikanth; Siesser, Priscila F.; Truscott, Harrison; Hajicek, Nicole; Sondek, John; Bear, James E.; Haugh, Jason M.

Genetic variants of phospholipase C-g2 alter the phenotype and function of microglia and confer differential risk for Alzheimer's disease

IMMUNITY

IF26.3

2023-09-01

OAAI

Tsai, Andy P.; Dong, Chuanpeng; Lin, Peter Bor-Chian; Oblak, Adrian L.; Di Prisco, Gonzalo Viana; Wang, Nian; Hajicek, Nicole; Carr, Adam J.; Lendy, Emma K.; Hahn, Oliver; Atkins, Micaiah; Foltz, Aulden G.; Patel, Jheel; Xu, Guixiang; Moutinho, Miguel; Sondek, John; Zhang, Qisheng; Mesecar, Andrew D.; Liu, Yunlong; Atwood, Brady K.; Wyss-Coray, Tony; Nho, Kwangsik; Bissel, Stephanie J.; Lamb, Bruce T.; Landreth, Gary E.

Inhibition of NF-κB activity by Iκ-Bβ in association with κB-Ras

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Chen, Y; Vallee, S; Wu, J; Vu, D; Sondek, J; Ghosh, G

RhoGEF specificity mutants implicate RhoA as a target for Dbs transforming activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Cheng, L; Rossman, KL; Mahon, GM; Worthylake, DK; Korus, M; Sondek, J; Whitehead, IP

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

ELIFE

IF0

2022-06-16

OAAI

Siraliev-Perez, Edhriz; Stariha, Jordan T. B.; Hoffmann, Reece M.; Temple, Brenda R. S.; Zhang, Qisheng; Hajicek, Nicole; Jenkins, Meredith L.; Burke, John E.; Sondek, John

Designer proteins that competitively inhibit Gαq by targeting its effector site

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-12-01

OAAI

Hussain, Mahmud; Cummins, Matthew C.; Endo-Streeter, Stuart; Sondek, John; Kuhlman, Brian

Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis 多重GTPase和GEF生物传感器成像可实现网络连接分析

NATURE CHEMICAL BIOLOGY

IF13.7

2020-05-18

OAAI

Marston, Daniel J.; Vilela, Marco; Huh, Jaewon; Ren, Jinqi; Azoitei, Mihai L.; Glekas, George; Danuser, Gaudenz; Sondek, John; Hahn, Klaus M.

Dynamics of allosteric activation in PLC-γ isozymes

FASEB JOURNAL

IF4.2

2020-04-16

OAAI

Siraliev-Perez, Edhriz; Hoffmann, Reece; Stariha, Jordan; Hajicek, Nicole; Burke, John; Sondek, John

Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancerassociated mutations

ELIFE

IF0

2019-12-31

OAAI

Hajicek, Nicole; Keith, Nicholas C.; Siraliev-Perez, Edhriz; Temple, Brenda R. S.; Huang, Weigang; Zhang, Qisheng; Harden, T. Kendall; Sondek, John

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways 由微管和Src介导的途径控制的GEF-H1激活的时空动力学

JOURNAL OF CELL BIOLOGY

IF6.4

2019-08-16

OAAI

Azoitei, Mihai L.; Noh, Jungsik; Marston, Daniel J.; Roudot, Philippe; Marshall, Christopher B.; Daugird, Timothy A.; Lisanza, Sidney L.; Sandi, Maria-Jose; Ikura, Mitsu; Sondek, John; Rottapel, Robert; Hahn, Klaus M.; Danuser, Gaudenz

Calcium-induced structural rearrangements release autoinhibition in the Rap-GEF CalDAG-GEFI

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-06-01

OAAI

Cook, Aaron A.; Deng, Wei; Ren, Jinqi; Li, Renhao; Sondek, John; Bergmeier, Wolfgang

A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes 哺乳动物磷脂酶C同工酶的膜相关荧光报告基因

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-02-01

OAAI

Huang, Weigang; Wang, Xiaoyang; Endo-Streeter, Stuart; Barrett, Matthew; Waybright, Jarod; Wohlfeld, Christian; Hajicek, Nicole; Harden, T. Kendall; Sondek, John; Zhang, Qisheng

TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-01-30

133

OAAI

Nishimura, Marc T.; Anderson, Ryan G.; Cherkis, Karen A.; Law, Terry F.; Liu, Qingli L.; Machius, Mischa; Nimchuk, Zachary L.; Yang, Li; Chung, Eui-Hwan; El Kasmi, Farid; Hyunh, Michael; Nishimura, Erin Osborne; Sondek, John E.; Dangl, Jeffery L.

Potent and Selective Peptide-based Inhibition of the G Protein Gq

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-12-01

OAAI

Charpentier, Thomas H.; Waldo, Gary L.; Lowery-Gionta, Emily G.; Krajewski, Krzysztof; Strahl, Brian D.; Kash, Thomas L.; Harden, T. Kendall; Sondek, John

Simultaneous Imaging of Rho GTPase and RhoGEF Activation using Novel GEF Biosensors Reveals Relationships between GEF and GTPase Activation in Cell Motility

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Marston, Daniel J.; Vilela, Marco; Glekas, George; Danuser, Gaudenz; Sondek, John; Hahn, Klaus M.

The experimental power of FR900359 to study Gq-regulated biological processes

NATURE COMMUNICATIONS

IF15.7

2015-12-14

296

OAAI

Schrage, Ramona; Schmitz, Anna-Lena; Gaffal, Evelyn; Annala, Suvi; Kehraus, Stefan; Wenzel, Daniela; Buellesbach, Katrin M.; Bald, Tobias; Inoue, Asuka; Shinjo, Yuji; Galandrin, Segolene; Shridhar, Naveen; Hesse, Michael; Grundmann, Manuel; Merten, Nicole; Charpentier, Thomas H.; Martz, Matthew; Butcher, Adrian J.; Slodczyk, Tanja; Armando, Sylvain; Effern, Maike; Namkung, Yoon; Jenkins, Laura; Horn, Velten; Stoessel, Anne; Dargatz, Harald; Tietze, Daniel; Imhof, Diana; Gales, Celine; Drewke, Christel; Mueller, Christa E.; Hoelzel, Michael; Milligan, Graeme; Tobin, Andrew B.; Gomeza, Jesus; Dohlman, Henrik G.; Sondek, John; Harden, T. Kendall; Bouvier, Michel; Laporte, Stephane A.; Aoki, Junken; Fleischmann, Bernd K.; Mohr, Klaus; Koenig, Gabriele M.; Tueting, Thomas; Kostenis, Evi

Membrane-induced Allosteric Control of Phospholipase C-β Isozymes 膜诱导的磷脂酶c-β 同工酶的变构控制

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2014-10-01

OAAI

Charpentier, Thomas H.; Waldo, Gary L.; Barrett, Matthew O.; Huang, Weigang; Zhang, Qisheng; Harden, T. Kendall; Sondek, John

Small Molecule Inhibitors of Phospholipase C from a Novel High-throughput Screen

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2013-02-01

OAAI

Huang, Weigang; Barrett, Matthew; Hajicek, Nicole; Hicks, Stephanie; Harden, T. Kendall; Sondek, John; Zhang, Qisheng

The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2012-11-15

OAAI

Fernandez-Pinar, Pablo; Aleman, Ainel; Sondek, John; Dohlman, Henrik G.; Molina, Maria; Martin, Humberto

A PLCβ/PI3Kγ-GSK3 Signaling Pathway Regulates Cofilin Phosphatase Slingshot2 and Neutrophil Polarization and Chemotaxis

DEVELOPMENTAL CELL

IF8.7

2011-12-01

OAAI

Tang, Wenwen; Zhang, Yong; Xu, Wenwen; Harden, T. Kendall; Sondek, John; Sun, Le; Li, Lin; Wu, Dianqing

研究方向