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Reuben J. Shaw

Salk Institute for Biological Studies

H指数:62

被引数:4.7万

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AMPK: a master regulator of mitochondrial quality and quantity

AMPK：线粒体质量和数量的主调控因子

Trends in Cell Biology

IF18.1

2026-05-120

OAAI

Modeling lipid homeostasis using stable isotope tracing and flux analysis

利用稳定同位素示踪和通量分析对脂质稳态进行建模

Cell Metabolism

IF30.9

2026-02-200

OAAI

FAM43A coordinates mtDNA replication and mitochondrial biogenesis in response to mtDNA depletion

FAM43A协调mtDNA复制和线粒体生物发生以响应mtDNA耗竭

JOURNAL OF CELL BIOLOGY

IF6.4

2025-01-270

PRE

Transcriptional repression by HDAC3 mediates T cell exclusion from Kras mutant lung tumors

HDAC3的转录抑制介导Kras突变型肺肿瘤的T细胞排斥

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-10-100

PRE

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

CANCER DISCOVERY

IF33.3

2024-01-258

PRE

Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

细胞器间串扰支持代谢应激下的乙酰辅酶a稳态和脂肪生成

SCIENCE ADVANCES

IF12.5

2023-05-0512

OAAI

HDAC3 is critical in tumor development and therapeutic resistance in Kras-mutant non-small cell lung cancer

SCIENCE ADVANCES

IF12.5

2023-03-1718

OAAI

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

CANCER DISCOVERY

IF33.3

2023-01-309

OAAI

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

AMPK介导的RIPK1磷酸化对细胞死亡的代谢协调

IF45.8

2023-01-010

OA

Tao Zhang; Daichao Xu; Elijah Trefts; Mingming Lv; Hiroyuki Inuzuka; Guobin Song; Min Liu; Jianlin Lu; Jianping Liu; Chen Chu; Min Wang; Huibing Wang; Huyan Meng; Hui Liu; Yuan Zhuang; Xingxing Xie; Fabin Dang; Dongxian Guan; Yuqin Men; Shuwen Jiang; Cong Jiang; Xiaoming Dai; Jing Liu; Zhen Wang; Peiqiang Yan; Jingchao Wang; Zhenbo Tu; Mrigya Babuta; Emily C. Erickson; Alissandra L. Hillis; Christian C. Dibble; John M. Asara; Gyongy Szabo; Piotr Siciński; Ji Miao; Yu-Ru Lee; Lifeng Pan; Reuben J. Shaw; Junying Yuan; Wenyi Wei

Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1

FNIP1的AMPK磷酸化诱导溶酶体和线粒体生物发生

IF45.8

2023-01-010

OA

Circadian disruption enhances HSF1 signaling and tumorigenesis in Kras-driven lung cancer

SCIENCE ADVANCES

IF12.5

2022-09-3020

OAAI

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

NATURE COMMUNICATIONS

IF15.7

2022-08-0149

OAAI

Leadership Diversity and Development in the Nation's Cancer Centers

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE

IF7.2

2022-07-2812

OA

Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter

NATURE COMMUNICATIONS

IF15.7

2022-07-0532

OAAI

Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in PolgD257A mice

SCIENCE ADVANCES

IF12.5

2021-10-1512

OAAI

AMPK: restoring metabolic homeostasis over space and time

AMPK: 恢复空间和时间上的代谢稳态

IF16.6

2021-09-01218

OAAI

Spatiotemporal Regulation of AMPK Revealed by a Sensitive Kinase Activity Reporterorter

IF4.2

2021-05-140

PRE

AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy

Parkin ACT结构域的AMPK/ULK1-mediated磷酸化介导线粒体吞噬的早期步骤

SCIENCE ADVANCES

IF12.5

2021-04-0999

OAAI

Inhibition of CAMKK2 impairs autophagy and castration-resistant prostate cancer via suppression of AMPK-ULK1 signaling

IF7.3

2021-02-0242

OAAI

Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-11-1737

OAAI