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T

Tony T. Huang

new york university grossman school of medicine

H指数:35

被引数:6,246

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Positional replication fork instability drives PARP inhibitor cytotoxicity

定位复制叉不稳定性驱动PARP抑制剂细胞毒性

Nature Cell Biology

IF19.1

2026-11-050

PRE

SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress

SLFN11拮抗RFWD3-PRIMPOL DNA损伤耐受轴以抑制复制应激反应中的缺口DNA合成

Nature Communications

IF15.7

2025-12-100

OAAI

Deubiquitinases cleave ubiquitin-fused ribosomal proteins and physically counteract their targeting to the UFD pathway

去泛素化酶切割泛素融合的核糖体蛋白，并物理性地对抗其靶向至UFD通路。

IF16.6

2025-11-200

OAAI

BRCA2 prevents PARPi-mediated PARP1 retention to protect RAD51 filaments

BRCA2通过抑制PARPi介导的PARP1滞留来保护RAD51丝状结构

IF48.5

2025-03-260

PRE

Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency

NATURE COMMUNICATIONS

IF15.7

2024-06-030

OAAI

Transcription-Replication Conflicts as a Source of Genome Instability

ANNUAL REVIEW OF GENETICS

IF8.6

2023-11-2713

OA

Confronting the loss of trophic support

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2023-06-230

OAAI

The zinc finger domain of NEMO is selectively required for NF-κB activation by UV radiation and topoisomerase inhibitors

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-04-01111

OAAI

Postrepression activation of NF-κB requires the amino-terminal nuclear export signal specific to IκBα

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28107

OAAI

Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2731

OAAI

Role of Deubiquitinating Enzymes in DNA Repair

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-1773

OAAI

USP1-trapping lesions as a source of DNA replication stress and genomic instability

NATURE COMMUNICATIONS

IF15.7

2022-04-0128

OAAI

Targeting SARS-CoV-2 Proteases for COVID-19 Antiviral Development

FRONTIERS IN CHEMISTRY

IF4.2

2022-02-0367

OAAI

Single-cell transcriptomics identifies Gadd45b as a regulator of herpesvirus-reactivating neurons

IF6.2

2021-11-2913

OA

A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease

IF6.9

2021-09-0136

OAAI

WEE1i-ATRi combination therapy: a promising low-dose treatment for CCNE1-amplified gynecologic cancers

CELL REPORTS MEDICINE

IF10.6

2021-09-014

OAAI

Fused in sarcoma regulates DNA replication timing and kinetics

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-09-0111

OAAI

FANCI functions as a repair/apoptosis switch in response to DNA crosslinks

DEVELOPMENTAL CELL

IF8.7

2021-08-0111

OA

Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling

NATURE COMMUNICATIONS

IF15.7

2021-05-0565

OAAI

Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian cells

NATURE PROTOCOLS

IF16

2021-01-136

OA