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G

Gregory J. Cost

Casebia Therapeutics
H指数:33
被引数:1.2万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Preclinical efficacy and safety assessment of engineered regulatory T cells for treatment of IPEX and other autoimmune disorders

工程化调节性T细胞治疗IPEX及其他自身免疫性疾病的疗效与安全性评估

Molecular Therapy
IF12
2026-03-130
PRE
Yuchi Honaker; Noelle P. Dahl; Swati Singh; Akhilesh K. Singh; Christina Lopez; David Gruber; Samuel C. Scharffenberger; Shivani Patel; Harold Jones; Iram F. Khan; Michelle L. Christian; Su Jung Yang; Karen Sommer; Troy R. Torgerson; Eric J. Allenspach; Cade Ellis K. Ito; Gene I. Uenishi; Gregory J. Cost; Peter J. Cook; David J. Rawlings
Integration of therapeutic cargo into the human genome with programmable type V-K CAST

利用可编程V-K型CAST将治疗性载荷整合到人类基因组中

NATURE COMMUNICATIONS
IF15.7
2025-03-131
OA
Liu, Jason; Goltsman, Daniela S. Aliaga; Alexander, Lisa M.; Khayi, Khak Khak; Hong, Jennifer H.; Dunham, Drew T.; Romano, Christine A.; Temoche-Diaz, Morayma M.; Chadha, Shailaja; Ocampo, Rodrigo Fregoso; Oki-O'Connell, Jennifer; Janson, Owen P.; Turcios, Keirstinne; Gonzalez-Osorio, Liliana; Muysson, Jared; Rahman, Jenat; Laperriere, Sarah M.; Devoto, Audra E.; Castelle, Cindy J.; Butterfield, Cristina N.; Cost, Gregory J.; Brown, Christopher T.; Thomas, Brian C.
AFNT-212: A TRAC-knocked-in KRASG12D-specific TCR-T cell product enhanced with CD8αß and a chimeric cytokine receptor for treatment of solid cancers
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Drain, Allison; Rouillard, Nicholas; Swanson, Nathaniel; Canestraro, Martina; Narayan, Santosh; Warner, Tyler; Danek, Nicole; Gareau, Ken; Liang, Jinsheng; Shen, Luhua; Tetrault, Tanya; Priyata, Iqraa; Vidyasagar, Sarah; Riggins-Walker, Taylor; Liu, Hui-Wen; Pechhold, Klaus; Brown, Lauren; Francis, Joshua; He, Xingyue; Browne, Patrick; Lamothe, Rebecca; Storlie, Meghan; Cost, Gregory; Schmitt, Thomas M.; Greenberg, Philip D.; Chandran, Smita S.; Klebanoff, Christopher A.; Lam, Hubert; Gupta, Ankit; Hallet, Damien; Shapiro, Gary; Nguyen, Kim; Vincent, Loic
Non-viral engineered T cell therapy specific for the hotspot mutation p53 R175H that integrates signal 1 (TCR), signal 2 ( co-stimulation) and signal 3 (cytokine) and co-opts FasL-dependent apoptosis to achieve a coordinated antitumor CD4/8 T cell response
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Narayan, Santosh; Gareau, Ken; Gupta, Ankit; Ferrell, Josh; Rouillard, Nicholas; Warner, Tyler; Liang, Jinsheng; Shen, Luhua; Tetrault, Tanya; Francis, Joshua; He, Xingyue; Browne, Patrick J.; Lamothe, Rebecca; Storlie, Meghan D.; Cost, Gregory J.; Schmitt, Thomas M.; Greenberg, Philip D.; Chandran, Smita S.; Hallet, Damien; Gormally, Michael; Klebanoff, Chistopher A.; Shapiro, Gary; Nguyen, Kim; Vincent, Loic
Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability
CRISPR JOURNAL
IF4
2023-06-012
OAAI
Alexander, Lisa M. M.; Goltsman, Daniela S. Aliaga S.; Liu, Jason; Lin, Jyun-Liang; Temoche-Diaz, Morayma M. M.; Laperriere, Sarah M. M.; Neerincx, Andreas; Bednarski, Christien; Knyphausen, Philipp; Cohnen, Andre; Albers, Justine; Gonzalez-Osorio, Liliana; Ocampo, Rodrigo Fregoso; Oki, Jennifer; Devoto, Audra E. E.; Castelle, Cindy J. J.; Lamothe, Rebecca C. C.; Cost, Gregory J. J.; Butterfield, Cristina N. N.; Thomas, Brian C. C.; Brown, Christopher T. T.
Correction of the Sickle-Cell Disease Mutation in Human Hematopoietic Stem/Progenitor Cells
MOLECULAR THERAPY
IF12
2015-05-010
OAAI
Hoban, Megan D.; Mendel, Matthew C.; Romero, Zulema; Kaufman, Michael L.; Joglekar, Alok V.; Ho, Michelle; Lumaquin, Dianne; Gray, David; Lill, Georgia R.; Cooper, Aaron R.; Urbinati, Fabrizia; Senadheera, Shantha; Zhu, Allen; Liu, Pei-Qi; Paschon, David E.; Zhang, Lei; Rebar, Edward J.; Wilber, Andrew; Wang, Xiaoyan; Gregory, Philip D.; Holmes, Michael C.; Reik, Andreas; Hollis, Roger P.; Kohn, Donald B.; Cost, Gregory J.

研究方向

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P
Philip D. Gregory
H 指数:78论文数:230被引数:3.6万
M
Michael C. Holmes
H 指数:57论文数:156被引数:2.3万
Y
Yolanda Santiago
H 指数:13论文数:30被引数:3,448
F
Fyodor D. Urnov
H 指数:54论文数:213被引数:2.4万
J
Jeffrey C. Miller
H 指数:56论文数:163被引数:2.2万
E
Edward J. Rebar
H 指数:52论文数:116被引数:2.2万
R
Rebecca Lamothe
H 指数:7论文数:26被引数:522
C
Cristina N. Butterfield
H 指数:13论文数:34被引数:3,799
B
Brian C. Thomas
H 指数:70论文数:171被引数:2.3万
C
Christopher T. Brown
H 指数:41论文数:149被引数:1.4万