David Cortez - Publications, H-index & Citations

David Cortez

vanderbilt university

69H指数

164论文数

2.3W被引数

收录论文 93

发表时间

FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability FET蛋白和PAR化依赖性凝聚体促进复制叉反转和基因组稳定性

Nature Communications

IF15.7

2026-06-30

OAAI

Celeste Giansanti; Jack C. Schultz; Jessica Jackson; Alessandro Vindigni; David Cortez

Distinct repair outcomes from single and convergent replication fork collapse 单染色体和汇聚复制叉坍塌的不同修复结果

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2026-05-27

OAAI

Sara C. Conwell; Khushi V. N. Patel; Savannah J. Weeks-Pollenz; Steven N. Dahmen; Matthew T. Cranford; William G. Dunphy; David T. Long; David Cortez; James M. Dewar

Leading and lagging strand abasic sites differentially affect vertebrate replisome progression but involve analogous bypass mechanisms 前导链和滞后链的脱嘌呤/脱嘧啶位点对脊椎动物复制体进程产生差异性影响，但涉及类似的 bypass 机制。

Nucleic Acids Research

IF13.1

2025-09-23

OAAI

Matthew T Cranford; Steven N Dahmen; David Cortez; James M Dewar

SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes SRBD1通过促进拓扑异构酶IIα在有丝分裂染色体上的定位来促进染色体分离

NATURE COMMUNICATIONS

IF15.7

2025-02-16

OAAI

Lovejoy, Courtney A.; Wessel, Sarah R.; Bhowmick, Rahul; Hatoyama, Yuki; Kanemaki, Masato T.; Zhao, Runxiang; Cortez, David

Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-03-11

OAAI

Balakrishnan, Swati; Adolph, Madison; Tsai, Miaw - Sheue; Akizuki, Tae; Gallagher, Kaitlyn; Cortez, David; Chazin, Walter J.

Mechanistic insights into how RADX regulates RAD51 nucleoprotein filaments to maintain genome stability and control replication stress responses

CANCER RESEARCH

IF16.6

2024-01-09

PREAI

Adolph, Madison; Balakrishnan, Swati; Chazin, Walter; Cortez, David

Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells

CELL REPORTS

IF6.9

2023-11-01

OAAI

Rua-Fernandez, Jorge; Lovejoy, Courtney A.; Mehta, Kavi P. M.; Paulin, Katherine A.; Toudji, Yasmine T.; Giansanti, Celeste; Elichman, Brandt F.; Cortez, David

Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability Integrator促进RNAPII去除，以防止转录复制冲突和基因组不稳定性

MOLECULAR CELL

IF16.6

2023-07-01

PREAI

Bhowmick, Rahul; Mehta, Kavi P. M.; Lerdrup, Mads; Cortez, David

DDB1 maintains genome integrity through regulation of Cdt1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

102

OAAI

Lovejoy, Courtney A.; Lock, Kimberli; Yenamandra, Ashwini; Cortez, David

The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

176

OAAI

Xu, Xin; Vaithiyalingam, Sivaraja; Glick, Gloria G.; Mordes, Daniel A.; Chazin, Walter J.; Cortez, David

Function of a conserved checkpoint recruitment domain in ATRIP proteins

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

153

OAAI

Ball, Heather L.; Ehrhardt, Mark R.; Mordes, Daniel A.; Glick, Gloria G.; Chazin, Walter J.; Cortez, David

Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Kavanaugh, Gina; Zhao, Runxiang; Guo, Yan; Mohni, Kareem N.; Glick, Gloria; Lacy, Monica E.; Hutson, M. Shane; Ascano, Manuel; Cortez, David

Replication fork uncoupling causes nascent strand degradation and fork reversal

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2023-01-02

OAAI

Kavlashvili, Tamar; Liu, Wenpeng; Mohamed, Taha M.; Cortez, David; Dewar, James M.

The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites and reversal of its DNA-protein cross-link

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-09-01

OAAI

Paulin, Katherine A.; Cortez, David; Eichman, Brandt F.

Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms

EMBO JOURNAL

IF8.3

2022-05-16

OAAI

Van Ravenstein, Sabrina X.; Mehta, Kavi P.; Kavlashvili, Tamar; Byl, Jo Ann W.; Zhao, Runxiang; Osheroff, Neil; Cortez, David; Dewar, James M.

CHK1 phosphorylates PRIMPOL to promote replication stress tolerance

SCIENCE ADVANCES

IF12.5

2022-04-01

OAAI

Mehta, Kavi P. M.; Thada, Vaughn; Zhao, Runxiang; Krishnamoorthy, Archana; Leser, Micheal; Rose, Kristie Lindsey; Cortez, David

Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-03-01

OAAI

Mohamed, Taha; Adolph, Madison B.; Cortez, David

RADX prevents genome instability by confining replication fork reversal to stalled forks

MOLECULAR CELL

IF16.6

2021-07-01

OAAI

Krishnamoorthy, Archana; Jackson, Jessica; Mohamed, Taha; Adolph, Madison; Vindigni, Alessandro; Cortez, David

Performance of a Point of Care Test for Detecting IgM and IgG Antibodies Against SARS-CoV-2 and Seroprevalence in Blood Donors and Health Care Workers in Panama

FRONTIERS IN MEDICINE

IF3

2021-03-02

OAAI

Villarreal, Alcibiades; Rangel, Giselle; Zhang, Xu; Wong, Digna; Britton, Gabrielle; Fernandez, Patricia L.; Perez, Ambar; Oviedo, Diana; Restrepo, Carlos; Carreirra, Maria B.; Sambrano, Dilcia; Eskildsen, Gilberto A.; De la Guardia, Carolina; Flores-Cuadra, Julio; Carrera, Jean-Paul; Zaldivar, Yamitzel; Franco, Danilo; Lopez-Verges, Sandra; Zhang, Dexi; Fan, Fangjing; Wang, Baojun; Saez-Llorens, Xavier; DeAntonio, Rodrigo; Torres-Atencio, Ivonne; Blanco, Isabel; Subia, Fernando Diaz; Mudarra, Laiss; Benzadon, Aron; Valverde, Walter; Lopez, Lineth; Hurtado, Nicolas; Rivas, Neyla; Jurado, Julio; Carvallo, Aixa; Rodriguez, Juan; Perez, Yaseikiry; Morris, Johanna; Luque, Odemaris; Cortez, David; Ortega-Barria, Eduardo; Kosagisharaf, Rao; Lleonart, Ricardo; Li, Chong; Goodridge, Amador

RADX controls RAD51 filament dynamics to regulate replication fork stability

MOLECULAR CELL

IF16.6

2021-03-01

OAAI

Adolph, Madison B.; Mohamed, Taha M.; Balakrishnan, Swati; Xue, Chaoyou; Morati, Florian; Modesti, Mauro; Greene, Eric C.; Chazin, Walter J.; Cortez, David

研究方向