Christopher Wells - Publications, H-index & Citations

Christopher Wells

Harvard University

28H指数

91论文数

6.1K被引数

收录论文 36

发表时间

Healthcare Resources Utilization and Costs of Patients with Non-IPF Progressive Fibrosing Interstitial Lung Disease Based on Insurance Claims in the USA 基于美国保险索赔的非IPF进行性纤维化间质性肺疾病患者的医疗资源利用和成本

ADVANCES IN THERAPY

IF4

2020-05-21

OAAI

Olson, Amy L.; Maher, Toby M.; Acciai, Valentina; Mounir, Baher; Quaresma, Manuel; Zouad-Lejour, Leila; Wells, Christopher D.; De Loureiro, Lou

Alternative transcription cycle for bacterial RNA polymerase

NATURE COMMUNICATIONS

IF15.7

2020-01-23

OAAI

Harden, Timothy T.; Herlambang, Karina S.; Chamberlain, Mathew; Lalanne, Jean-Benoit; Wells, Christopher D.; Li, Gene-Wei; Landick, Robert; Hochschild, Ann; Kondev, Jane; Gelles, Jeff

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

SCIENCE ADVANCES

IF12.5

2016-10-07

OAAI

Picaud, Sarah; Leonards, Katharina; Lambert, Jean-Philippe; Dovey, Oliver; Wells, Christopher; Fedorov, Oleg; Monteiro, Octovia; Fujisawa, Takao; Wang, Chen-Yi; Lingard, Hannah; Tallant, Cynthia; Nikbin, Nikzad; Guetzoyan, Lucie; Ingham, Richard; Ley, Steven V.; Brennan, Paul; Muller, Susanne; Samsonova, Anastasia; Gingras, Anne-Claude; Schwaller, Juerg; Vassiliou, George; Knapp, Stefan; Filippakopoulos, Panagis

Bacterial RNA polymerase can retain σ70 throughout transcription

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-01-05

OAAI

Harden, Timothy T.; Wells, Christopher D.; Friedman, Larry J.; Landick, Robert; Hochschild, Ann; Kondev, Jane; Gelles, Jeff

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

CANCER RESEARCH

IF16.6

2015-11-30

201

OAAI

Picaud, Sarah; Fedorov, Oleg; Thanasopoulou, Angeliki; Leonards, Katharina; Jones, Katherine; Meier, Julia; Olzscha, Heidi; Monteiro, Octovia; Martin, Sarah; Philpott, Martin; Tumber, Anthony; Filippakopoulos, Panagis; Yapp, Clarence; Wells, Christopher; Che, Ka Hing; Bannister, Andrew; Robson, Samuel; Kumar, Umesh; Parr, Nigel; Lee, Kevin; Lugo, Dave; Jeffrey, Philip; Taylor, Simon; Vecellio, Matteo L.; Bountra, Chas; Brennan, Paul E.; O'Mahony, Alison; Velichko, Sharlene; Mueller, Susanne; Hay, Duncan; Daniels, Danette L.; Urh, Marjeta; La Thangue, Nicholas B.; Kouzarides, Tony; Prinjha, Rab; Schwaller, Juerg; Knapp, Stefan

Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance

SCIENCE ADVANCES

IF12.5

2015-11-06

122

OAAI

Fedorov, Oleg; Castex, Josefina; Tallant, Cynthia; Owen, Dafydd R.; Martin, Sarah; Aldeghi, Matteo; Monteiro, Octovia; Filippakopoulos, Panagis; Picaud, Sarah; Trzupek, John D.; Gerstenberger, Brian S.; Bountra, Chas; Willmann, Dominica; Wells, Christopher; Philpott, Martin; Rogers, Catherine; Biggin, Philip C.; Brennan, Paul E.; Bunnage, Mark E.; Schuele, Roland; Guenther, Thomas; Knapp, Stefan; Mueller, Susanne

The primary σ factor in Escherichia coli can access the transcription elongation complex from solution in vivo

ELIFE

IF0

2015-09-15

OAAI

Goldman, Seth R.; Nair, Nikhil U.; Wells, Christopher D.; Nickels, Bryce E.; Hochschild, Ann

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-08-10

219

OAAI

Hammitzsch, Ariane; Tallant, Cynthia; Fedorov, Oleg; O'Mahony, Alison; Brennan, Paul E.; Hay, Duncan A.; Martinez, Fernando O.; Al-Mossawi, M. Hussein; de Wit, Jelle; Vecellio, Matteo; Wells, Christopher; Wordsworth, Paul; Mueller, Susanne; Knapp, Stefan; Bowness, Paul

Bacterial Transcript Elongation Complexes can Retain Sigma Factor throughout RNA Synthesis

BIOPHYSICAL JOURNAL

IF3.1

2015-01-01

OAAI

Harden, Timothy T.; Friedman, Larry J.; Wells, Christopher D.; Hochschild, Ann; Kondev, Jane; Gelles, Jeff

Dual kinase/bromodomain inhibitors for rationally designed polypharmacology

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Quinn, Elizabeth R.; Ciceri, Pietro; Mueller-Knapp, Susanne; O'Mahony, Alison; Fedorov, Oleg; Filippakopoulos, Panagis; Hunt, Jeremy P.; Lasater, Elisabeth A.; Pallares, Gabriel; Picaud, Sarah; Wells, Christopher; Wodicka, Lisa M.; Shah, Neil P.; Knapp, Stefan; Treiber, Daniel K.

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology (vol 10, pg 305, 2014)

NATURE CHEMICAL BIOLOGY

IF13.7

2014-07-18

OAAI

Ciceri, Pietro; Mueller, Susanne; O'Mahony, Alison; Fedorov, Oleg; Filippakopoulos, Panagis; Hunt, Jeremy P.; Lasater, Elisabeth A.; Pallares, Gabriel; Picaud, Sarah; Wells, Christopher; Martin, Sarah; Wodicka, Lisa M.; Shah, Neil P.; Treiber, Daniel K.; Knapp, Stefan

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2014-06-19

286

OAAI

Hay, Duncan A.; Fedorov, Oleg; Martin, Sarah; Singleton, Dean C.; Tallant, Cynthia; Wells, Christopher; Picaud, Sarah; Philpott, Martin; Monteiro, Octovia P.; Rogers, Catherine M.; Conway, Stuart J.; Rooney, Timothy P. C.; Tumber, Anthony; Yapp, Clarence; Filippakopoulos, Panagis; Bunnage, Mark E.; Mueller, Susanne; Knapp, Stefan; Schofield, Christopher J.; Brennan, Paul E.

Untitled Response

PAIN

IF5.5

2014-05-01

PREAI

Dworkin, Robert H.; O'Connor, Alec B.; Kent, Joel; Mackey, Sean C.; Raja, Srinivasa N.; Stacey, Brett R.; Levy, Robert M.; Backonja, Miroslav; Baron, Ralf; Harke, Henning; Loeser, John D.; Treede, Rolf-Detlef; Turk, Dennis C.; Wells, Christopher D.

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

NATURE CHEMICAL BIOLOGY

IF13.7

2014-03-02

315

OAAI

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-11-18

457

OAAI

Picaud, Sarah; Wells, Christopher; Felletar, Ildiko; Brotherton, Deborah; Martin, Sarah; Savitsky, Pavel; Diez-Dacal, Beatriz; Philpott, Martin; Bountra, Chas; Lingard, Hannah; Fedorov, Oleg; Mueller, Susanne; Brennan, Paul E.; Knapp, Stefan; Filippakopoulos, Panagis

Interventional management of neuropathic pain: NeuPSIG recommendations

PAIN

IF5.5

2013-11-01

371

OAAI

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-04-05

150

OAAI

Hewings, David S.; Fedorov, Oleg; Filippakopoulos, Panagis; Martin, Sarah; Picaud, Sarah; Tumber, Anthony; Wells, Christopher; Olcina, Monica M.; Freeman, Katherine; Gill, Andrew; Ritchie, Alison J.; Sheppard, David W.; Russell, Angela J.; Hammond, Ester M.; Knapp, Stefan; Brennan, Paul E.; Conway, Stuart J.

LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap

ONCOGENE

IF7.3

2012-10-01

OAAI

Nguyen, H. B.; Babcock, J. T.; Wells, C. D.; Quilliam, L. A.

Recommendations for the Pharmacological Management of Neuropathic Pain: An Overview and Literature Update

MAYO CLINIC PROCEEDINGS

IF6.7

2010-03-01

999

OAAI

Dworkin, Robert H.; O'Connor, Alec B.; Audette, Joseph; Baron, Ralf; Gourlay, Geoffrey K.; Haanpaa, Maija L.; Kent, Joel L.; Krane, Elliot J.; LeBel, Alyssa A.; Levy, Robert M.; Mackey, Sean C.; Mayer, John; Miaskowski, Christine; Raja, Srinivasa N.; Rice, Andrew S. C.; Schmader, Kenneth E.; Stacey, Brett; Stanos, Steven; Treede, Rolf-Detlef; Turk, Dennis C.; Walco, Gary A.; Wells, Christopher D.

Treatment Considerations for Patients With Neuropathic Pain and Other Medical Comorbidities

MAYO CLINIC PROCEEDINGS

IF6.7

2010-03-01

OAAI

Haanpaa, Maija L.; Gourlay, Geoffrey K.; Kent, Joel L.; Miaskowski, Christine; Raja, Srinivasa N.; Schmader, Kenneth E.; Wells, Christopher D.

研究方向