logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
C

Christopher J. Schofield

Liverpool School of Tropical Medicine
H指数:112
被引数:6.2万

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Time-resolved ligand dynamics revealed in a β-lactamase using room-temperature serial crystallography

在β-内酰胺酶中利用室温串行晶体学揭示的时间分辨配体动力学

Communications Chemistry
IF6.2
2026-11-040
OAAI
Philip Hinchliffe; Catherine L. Tooke; Michael Beer; Pierre Aller; Jos J. A. G. Kamps; Laura Parkinson; Tiankun Zhou; Nicholas Devenish; Do-Heon Gu; Anastasya Shilova; Matthew J. Rodrigues; Abbey Telfer; Agata Butryn; Marko Hanževački; Emily I. Freeman; Sehan Park; Christopher J. Schofield; Jaehyun Park; Robin L. Owen; Adrian J. Mulholland; Allen M. Orville; James Spencer
Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies

异噁唑霉素N合成酶催化过程中通过时间分辨X射线自由电子激光研究鉴定出的非预期中间体

Nature Catalysis
IF44.6
2026-10-090
OAAI
Patrick Rabe; Hiroki Makita; Rebecca Southwart; Midhun George Thomas; Mihails Kazaks; Shyam Basak; Tiankun Zhou; William K. Myers; Margaret D. Doyle; Philipp S. Simon; Shusaku Hayama; J. Frederick W. Mosselmans; Alexander T. Stead; Abraham O. Oluwole; Malkit Sami; Ian Clifton; Pierre Aller; Asmit Bhowmick; Anthony Tumber; Jos J. A. G. Kamps; Karina Calvopiña; Agata Butryn; Robert Bosman; Arjun Cheema; Jordan Welsh; James D. S. Linyard; Frederick J. H. Foster; Pauline A. Lang; Mariska de Munnik; Stephen M. Keable; Medhanjali Dasgupta; In-Sik Kim; Isabel Bogacz; Kuntal Chatterjee; Kyle D. Sutherlin; Corey J. Kaminsky; Jürgen Brem; Michael A. McDonough; Christina Redfield; James R. D. Montgomery; Coral Mycroft; Anastasya Shilova; Nicholas Devenish; Frederic P. Poitevin; Sebastian Dehe; Vandana Tiwari; Humberto Sanchez; Daniel J. Rosenberg; Mark S. Hunter; Leland B. Gee; Uwe Bergmann; Roberto Alonso-Mori; Jaehyun Park; Shigeki Owada; Kensuke Tono; Danny Axford; Robin L. Owen; Daniel W. Paley; Nicholas K. Sauter; David Mittan-Moreau; Aaron S. Brewster; Carol V. Robinson; Vittal K. Yachandra; Junko Yano; Edgars Suna; Christo Z. Christov; Allen M. Orville; Jan F. Kern; Christopher J. Schofield
Substrate-Selective Inhibition of the SARS-CoV-2 Papain-Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

底物选择性抑制SARS-CoV-2木瓜蛋白酶样蛋白酶：抑制人源底物相对于病毒底物的水解

Chemistry – A European Journal
IF0
2026-06-120
OAAI
Sakshi Sharma; Peter A. C. Wing; Wojtek Trede; Shyam Basak; Simeon D. Draganov; Taylah Andrews-Clark; Eidarus Salah; Petra Lukacik; Claire Strain-Damerell; Adán Pinto-Fernández; Martin A. Walsh; Fernanda Duarte; Christopher J. Schofield; Lennart Brewitz
Development of Water-Trapping Pyrrole-2-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors

水捕获吡咯-2-羧酸类化合物的开发作为广谱金属β-内酰胺酶抑制剂

Journal of Medicinal Chemistry
IF6.8
2026-05-140
OA
Monisha Singha; Liam A. Wilson; Elisabete C. C. M. Moura; Maria M. Trush; Karina Calvopina; Gurleen Kaur; Greta Zaborskytė; Toms Kalniņš; Tharindi Panduwawala; Matthew J. Bowen; Matthew J. Beech; Jürgen Brem; Peter J. McHugh; Edgars Suna; Timothy R. Walsh; Christopher J. Schofield; Alistair J. M. Farley
β-Lactam antibiotics and β-lactamases: historical perspectives and a review of β-lactamase inhibitors derived from natural products

β-内酰胺类抗生素和β-内酰胺酶：历史回顾及源自天然产物的β-内酰胺酶抑制剂的综述

nat. prod. rep.
IF0
2026-04-230
OA
Phanankosi Moyo †; Ikhane O. Albert †; Neo Hlungwani; Thulani Sibanda; Perfoy Lumu; Ndivhuwo Kevin Khorommbi; Gurleen Kaur; Karina Calvopina Tapia; George Siegwart; Nana Kwaku Buabeng; Cynthia A. Danquah; Lyndy J. McGaw; Sekelwa Cosa; Christopher J. Schofield; Vinesh J. Maharaj
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9

KDM3A催化组蛋白H3K9上的乙酰基-赖氨酸氧化为羟基乙酰基-赖氨酸

Nature Chemistry
IF20.2
2026-04-150
OAAI
Roman Belle; John-Paul Bukowski; Rachel Schiller; Ronald Cutler; Eidarus Salah; Robert S. Dawber; Anthony Tumber; Joanna Bonnici; Jessica D. Kindrick; Loane Serrano; Patrick Rabe; Catrine Johansson; Marie-Hélène Ruchaud; Richard J. Hopkinson; William D. Figg, Sr; Paul E. Brennan; David R. Mole; Simone Sidoli; Akane Kawamura; Christopher J. Schofield
Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase

非常规Fe(II)和2-氧戊二酸依赖性人天冬氨酸/天冬酰胺-β-羟化酶的底物不专一性的结构基础

Nature Communications
IF15.7
2026-02-250
OAAI
Mariska de Munnik; Amelia Brasnett; Tiankun Zhou; William Myers; Yicheng Wang; Kuntal Chatterjee; Anthony Tumber; Stephen A. Marshall; Philipp S. Simon; Pierre Aller; Anastasiia Shilova; Danny Axford; Hiroki Makita; Daniel W. Paley; Vandana Tiwari; Alexander T. Stead; Sebastian Dehe; Humberto Sanchez; Daniel J. Rosenberg; Roberto Alonso-Mori; Asmit Bhowmick; Junko Yano; Vittal K. Yachandra; Jaehyun Park; Sehan Park; Allen M. Orville; Lennart Brewitz; Jan F. Kern; Christopher J. Schofield; Patrick Rabe
In Vitro and In Vivo Evaluation of Nitroxoline as an Effective Antimicrobial Alternative to Poultry Production

体外和体内评估：将Nitroxoline作为家禽生产中有效的抗菌替代品

Antibiotics
IF0
2026-01-070
OAAI
Yuqing Zhou; Maria M. Trush; Lewis Ibbotson; Laura Espina; Aditya Kumar Lankapalli; Alistair J. M. Farley; Huangwei Song; Congming Wu; Xingyuan Cao; Xi Xia; Charlotte J. Gray-Hammerton; Alice Moorey; Amelie Delaitre; George Siegwart; Shaolin Wang; Yang Wang; Jianzhong Shen; Christopher J. Schofield; Timothy R. Walsh
Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB

证据表明人类FTO催化<i>N</i><sub>6</sub>-甲基腺苷的羟化作用，而不直接形成脱甲基产物，这与ALKBH5/2/3和细菌AlkB形成对比。

Nucleic Acids Research
IF13.1
2025-08-280
OAAI
Simranjeet Kaur; Pratheesh Maheswaran; Samanpreet Kaur; Yingqi Lai; Eidarus Salah; Dong Zhang; Shifali Shishodia; Christopher J Schofield; Wei Shen Aik

研究方向

暂未获取到该数据
M
M.A. McDonough
H 指数:55论文数:282被引数:1.2万
A
Anthony Tumber
H 指数:41论文数:206被引数:7,482
J
Jürgen Brem
H 指数:35论文数:148被引数:3,725
A
Akane Kawamura
H 指数:43论文数:189被引数:6,765
T
Timothy D. W. Claridge
H 指数:62论文数:519被引数:1.5万
R
Rasheduzzaman Chowdhury
H 指数:40论文数:155被引数:6,984
P
Peter J. Ratcliffe
H 指数:125论文数:634被引数:7.7万
L
Lennart Brewitz
H 指数:21论文数:111被引数:1,474
M
Martine I. Abboud
H 指数:25论文数:81被引数:1,881
J
James Spencer
H 指数:60论文数:326被引数:1.6万