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J

Jochen Spiegel

university of cambridge

H指数:16

被引数:4,402

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Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras

利用G4配体靶向蛋白降解嵌合体降解染色质中的G-四链体结合蛋白

Nature Chemistry

IF20.2

2026-03-011

PRE

Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch

利用靶向DNA G-四链体的可逆光开关对基因表达进行光学控制

NATURE CHEMISTRY

IF20.2

2025-04-030

OA

Chem-map profiles drug binding to chromatin in cells

NATURE BIOTECHNOLOGY

IF41.7

2023-01-2316

OAAI

DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-12-0931

OAAI

Chemical profiling of DNA G-quadruplex-interacting proteins in live cells

NATURE CHEMISTRY

IF20.2

2021-06-2885

OAAI

G-quadruplexes are transcription factor binding hubs in human chromatin

G-四链体是人类染色质中的转录因子结合枢纽

IF9.4

2021-04-23136

OAAI

The regulation and functions of DNA and RNA G-quadruplexes

DNA和RNA G-四链体的调控和功能

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2020-04-20751

OAAI

The Structure and Function of DNA G-Quadruplexes

TRENDS IN CHEMISTRY

IF13.6

2020-02-01557

OAAI

DNA G-quadruplex structures mold the DNA methylome

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2018-10-01181

OAAI

Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing

NATURE PROTOCOLS

IF16

2018-02-22206

PREAI

Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase

ACS CHEMICAL BIOLOGY

IF3.8

2016-07-1173

PREAI

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

NATURE COMMUNICATIONS

IF15.7

2016-04-1490

OAAI

Direct Modulation of Small GTPase Activity and Function

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2015-10-1667

PREAI

Hydrocarbon Stapled Peptides as Modulators of Biological Function

ACS CHEMICAL BIOLOGY

IF3.8

2015-03-31273

PREAI

Small-molecule modulation of Ras signaling

NATURE CHEMICAL BIOLOGY

IF13.7

2014-06-15233

PREAI

Direct Targeting of Rab-GTPase-Effector Interactions**

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2014-01-3183

PREAI

Cyclic Aza-peptide Integrin Ligand Synthesis and Biological Activity

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2012-06-0444

PREAI

Azapeptides and their therapeutic potential

FUTURE MEDICINAL CHEMISTRY

IF3.4

2011-08-01151

PREAI