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S

Shoukat Dedhar

Department of Basic and Translational Research

100H指数
446论文数
3.5W被引数
收录论文 163
发表时间
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Survival of cancer cells following taxol-induced apoptosis is supported by ZEB1-mediated ferroptosis sensitivityTaxol诱导凋亡后癌细胞的存活受ZEB1介导的铁死亡敏感性的支持
errCell Death & Disease
IF9.6
err2026-09-02
err0
errOAAI
errRachel Hausman; Wells S. Brown; Shannon J. Awrey; Hossein Tavakoli; Denise J. Montell; Paul C. McDonald; Shoukat Dedhar
err分享
err收藏
Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death联合抑制碳酸酐酶IX和谷胱甘肽过氧化物酶4作为铁死亡诱导的肿瘤细胞死亡的新型策略
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-09-02
err0
PREAI
errGioele Renzi; Paul C. McDonald; Shannon Awrey; Hossein Tavakoli; Zahra Bokhari; Michael Lyle; Zaihui Zhang; Marta Ferraroni; Shoukat Dedhar; Claudiu T. Supuran; Andrea Angeli
err分享
err收藏
Neutrophil extracellular trap gene expression signatures identify prognostic and targetable signaling axes for inhibiting pancreatic tumour metastasis中性粒细胞胞外陷阱基因表达特征识别用于抑制胰腺肿瘤转移的预后和可靶向信号轴
errCommunications Biology
IF5.1
err2025-07-04
err0
errOAAI
errPaul C. McDonald; James T. Topham; Shannon Awrey; Hossein Tavakoli; Rebekah Carroll; Wells S. Brown; Zachary J. Gerbec; Steve E. Kalloger; Joanna M. Karasinska; Patricia Tang; Rachel Goodwin; Steven J. M. Jones; Janessa Laskin; Marco A. Marra; Gregg B. Morin; Daniel J. Renouf; David F. Schaeffer; Shoukat Dedhar
err分享
err收藏
Identification of intratumoral bacteria that enhance breast tumor metastasis
errMBIO
IF4.7
err2025-02-11
err0
errOAAI
errGerbec, Zachary J.; Serapio-Palacios, Antonio; Metcalfe-Roach, Avril; Krekhno, Zakhar; Bar-Yoseph, Haggai; Woodward, Sarah E.; Pena-Diaz, Jorge; Nemirovsky, Oksana; Awrey, Shannon; Moreno, Sebastian H.; Beatty, Sean; Kong, Esther; Radisavljevic, Nina; Cirstea, Mihai; Chafe, Shawn; Mcdonald, Paul C.; Aparicio, Sam; Finlay, B. Brett; Dedhar, Shoukat
err分享
err收藏
Several birds with one stone: exploring the potential of AI methods for multi-target drug design
errMOLECULAR DIVERSITY
IF3.8
err2024-11-24
err0
PREAI
errMukaidaisi, Muhetaer; Ahmed, Madiha; Grantham, Karl; Al-Jumaily, Aws; Dedhar, Shoukat; Organ, Michael; Tchagang, Alain; Hou, Jinqiang; Ahmed, Syed Ejaz; Dividino, Renata; Li, Yifeng
err分享
err收藏
Pancreatic cancer tumor organoids exhibit subtype-specific differences in metabolic profiles胰腺癌肿瘤类器官在代谢谱中表现出亚型特异性差异
errCANCER & METABOLISM
IF5.3
err2024-10-03
err0
errOAAI
errAli, Hassan A.; Karasinska, Joanna M.; Topham, James T.; Johal, Danisha; Kalloger, Steve; Metcalfe, Andrew; Warren, Cassia S.; Miyagi, Anthony; Tao, Lan V.; Kevorkova, Maya; Chafe, Shawn C.; Mcdonald, Paul C.; Dedhar, Shoukat; Parker, Seth J.; Renouf, Daniel J.; Schaeffer, David F.
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Combination treatment with histone deacetylase and carbonic anhydrase 9 inhibitors shows therapeutic potential in experimental diffuse intrinsic pontine glioma组蛋白去乙酰化酶和碳酸酐酶9抑制剂的联合治疗在实验性弥漫性内生性脑桥胶质瘤中显示出治疗潜力
errBrain Tumor Pathology
IF3
err2024-09-24
err0
PREAI
errNaohide Fujita; Andrew Bondoc; Sergio Simoes; Joji Ishida; Michael S. Taccone; Amanda Luck; Dilakshan Srikanthan; Robert Siddaway; Adrian Levine; Nesrin Sabha; Stacey Krumholtz; Akihide Kondo; Hajime Arai; Christian Smith; Paul McDonald; Cynthia Hawkins; Shoukat Dedhar; James Rutka
err分享
err收藏
PrP© controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up
errONCOGENE
IF7.3
err2024-08-15
err0
errOAAI
errLailler, Claire; Didelot, Audrey; Garinet, Simon; Berthou, Hugo; Sroussi, Marine; de Reynies, Aurelien; Dedhar, Shoukat; Martin-Lanneree, Severine; Fabre, Elizabeth; Le Pimpec-Barthes, Francoise; Perrier, Alexandre; Poindessous, Virginie; Mansuet-Lupo, Audrey; Djouadi, Fatima; Launay, Jean-Marie; Laurent-Puig, Pierre; Blons, Helene; Mouillet-Richard, Sophie
err分享
err收藏
Increased ferroptosis sensitivity and epithelial to mesenchymal transition of breast cancer cells overcoming chemotherapeutic mediated apoptotic caspase activation
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHausman, Rachel; Brown, Wells; McDonald, Paul; Awrey, Shannon; Sun, Gongping; Montell, Denise; Dedhar, Shoukat
err分享
err收藏
Neutrophil extracellular trap (NET)-induced pancreatic tumor metastasis requires integrin-linked kinase (ILK) signaling
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errMcDonald, Paul C.; Awrey, Shannon J.; Tavakoli, Hossein; Carroll, Rebekah; Gerbec, Zachary J.; Karasinska, Joanna M.; Schaeffer, David F.; Renouf, Daniel J.; Dedhar, Shoukat
err分享
err收藏
Persister cell plasticity in tumour drug resistance
errSEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
IF6
err2024-03-01
err6
PREAI
errMcdonald, Paul C.; Dedhar, Shoukat
err分享
err收藏
Co-vulnerabilities of inhibiting carbonic anhydrase IX in ferroptosis-mediated tumor cell death抑制碳酸酐酶IX在铁死亡介导的肿瘤细胞死亡中的共同脆弱性
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-11-30
err3
errOAAI
errMcDonald, Paul C.; Dedhar, Shoukat
err分享
err收藏
A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells碳酸酐酶IX/SLC1A5轴调节缺氧肿瘤细胞中谷氨酰胺代谢依赖性铁死亡
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-06-22
err12
errOAAI
errVenkateswaran, Geetha; McDonald, Paul C.; Chafe, Shawn C.; Brown, Wells S.; Gerbec, Zachary J.; Awrey, Shannon J.; Parker, Seth J.; Dedhar, Shoukat
err分享
err收藏
Tumor-derived bacteria drive breast cancer metastasis
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errGerbec, Zachary J.; Serapio-Palacios, Antonio; Woodward, Sarah; Pena-Diaz, Jorge; Finlay, B. Brett; Dedhar, Shoukat
err分享
err收藏
Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err58
errOAAI
errLiu, E; Sinha, S; Williams, C; Cyrille, M; Heller, E; Snapper, SB; Georgopoulos, K; St-Arnaud, R; Force, T; Dedhar, S; Gerszten, RE
err分享
err收藏
Integrin-linked kinase regulates endothelial cell survival and vascular development
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err139
errOAAI
errFriedrich, EB; Liu, E; Sinha, S; Cook, S; Milstone, DS; MacRae, CA; Mariotti, M; Kuhlencordt, PJ; Force, T; Rosenzweig, A; St-Arnaud, R; Dedhar, S; Gerszten, RE
err分享
err收藏
Tumor- derived bacteria drive breast cancer metastasis
errCANCER RESEARCH
IF16.6
err2023-01-15
err0
PREAI
errGerbec, Zachary J.; Serapio-Palacios, Antonio; Woodword, Sarah E.; Diaz, Jorge Pena; Finlay, Brett; Dedhar, Shoukat
err分享
err收藏
Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX
errMABS
IF7.3
err2021-11-23
err3
errOAAI
errSheff, Joey G.; Kelly, John F.; Robotham, Anna; Sulea, Traian; Malenfant, Felix; L'Abbe, Denis; Duchesne, Melanie; Pelletier, Alex; Lefebvre, Jean; Acel, Andrea; Parat, Marie; Gosselin, Mylene; Wu, Cunle; Fortin, Yves; Baardsnes, Jason; Van Faassen, Henk; Awrey, Shannon; Chafe, Shawn C.; McDonald, Paul C.; Dedhar, Shoukat; Lenferink, Anne E. G.
err分享
err收藏
Isolation and characterization of monoclonal antibodies against human carbonic anhydrase-IX抗人碳酸酐酶-IX单克隆抗体的隔离与鉴定
errMABS
IF7.3
err2021-11-21
err6
errOAAI
errLenferink, Anne E. G.; McDonald, Paul C.; Cantin, Christiane; Grothe, Suzanne; Gosselin, Mylene; Baardsnes, Jason; Banville, Myriam; Lachance, Paul; Robert, Alma; Cepero-Donates, Yuneivy; Radinovic, Stevo; Salois, Patrick; Parat, Marie; Oamari, Hafida; Dulude, Annie; Patel, Mehul; Lafrance, Martin; Acel, Andrea; Bousquet-Gagnon, Nathalie; L'Abbe, Denis; Pelletier, Alex; Malenfant, Felix; Jaramillo, Maria; O'Connor-Mccourt, Maureen; Wu, Cunle; Durocher, Yves; Duchesne, Melanie; Gadoury, Christine; Marcil, Anne; Fortin, Yves; Paul-Roc, Beatrice; Acchione, Maurizio; Chafe, Shawn C.; Nemirovsky, Oksana; Lau, Joseph; Benard, Francois; Dedhar, Shoukat
err分享
err收藏
Guidelines and definitions for research on epithelial-mesenchymal transition (vol 21, pg 341, 2020)上皮-间质转化研究指南和定义 (第21卷，341页，2020)
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2021-10-15
err15
errOAAI
errYang, Jing; Antin, Parker; Berx, Geert; Blanpain, Cedric; Brabletz, Thomas; Bronner, Marianne; Campbell, Kyra; Cano, Amparo; Casanova, Jordi; Christofori, Gerhard; Dedhar, Shoukat; Derynck, Rik; Ford, Heide L.; Fuxe, Jonas; Garcia de Herreros, Antonio; Goodall, Gregory J.; Hadjantonakis, Anna-Katerina; Huang, Ruby Y. J.; Kalcheim, Chaya; Kalluri, Raghu; Kang, Yibin; Khew-Goodall, Yeesim; Levine, Herbert; Liu, Jinsong; Longmore, Gregory D.; Mani, Sendurai A.; Massague, Joan; Mayor, Roberto; McClay, David; Mostov, Keith E.; Newgreen, Donald F.; Nieto, M. Angela; Puisieux, Alain; Runyan, Raymond; Savagner, Pierre; Stanger, Ben; Stemmler, Marc P.; Takahashi, Yoshiko; Takeichi, Masatoshi; Theveneau, Eric; Thiery, Jean Paul; Thompson, Erik W.; Weinberg, Robert A.; Williams, Elizabeth D.; Xing, Jianhua; Zhou, Binhua P.; Sheng, Guojun
err分享
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