Thanos D. Halazonetis - Publications, H-index & Citations

Thanos D. Halazonetis

university of geneva

61H指数

184论文数

2.4W被引数

收录论文 81

发表时间

OCT4 enhances the firing efficiency of late DNA replication origins in mouse embryonic stem cells OCT4增强小鼠胚胎干细胞中晚期DNA复制起点的点火效率

Nature Communications

IF15.7

2026-01-15

OAAI

Eddie Rodriguez-Carballo; Vasilis S. Dionellis; Sotirios G. Ntallis; Lilia Bernasconi; Ezgi G. Keskin; Thanos D. Halazonetis

CldU sensitizes BRCA2 reverse-mutated cells to PARP inhibitors CldU 使 BRCA2 反向突变细胞对 PARP 抑制剂更敏感

Frontiers in Oncology

IF3.3

2025-11-19

OAAI

Nawel Zouggari†; Camilla Trugenberger†; Valentine Du Bois; Wenwen Wang; Giacomo G. Rossetti; Thanos D. Halazonetis; Intidhar Labidi-Galy

RECQL4 is not critical for firing of human DNA replication origins

SCIENTIFIC REPORTS

IF3.9

2024-04-02

OAAI

Padayachy, Laura; Ntallis, Sotirios G.; Halazonetis, Thanos D.

FoRx-06-428 is a novel PARG inhibitor with potent anti-tumor efficacy in preclinical cancer models

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Querolle, Olivier; Lucking, Ulrich; Iacovino, Luca; Freudenmann, Alena; Rossetti, Giacomo; Gysin, Marina; Bologna, Serena; Dionellis, Vasilis; Malattia, Marta; Potenza, Alessandro; Bocquet, Nicolas; Konstantinova, Irena; Goutopoulos, Andreas; Sotiriou, Sotirios; Halazonetis, Thanos; Bashir, Tarig; Zenke, Frank

Homozygous substitution of threonine 191 by proline in polymerase η causes Xeroderma pigmentosum variant

SCIENTIFIC REPORTS

IF3.9

2024-01-11

OAAI

Ricciardiello, Roberto; Forleo, Giulia; Cipolla, Lina; van Winckel, Geraldine; Marconi, Caterina; Nouspikel, Thierry; Halazonetis, Thanos D.; Zgheib, Omar; Sabbioneda, Simone

Insights into DNA Damage in Regenerating Young and Aged Mouse Livers

BRITISH JOURNAL OF SURGERY

IF8.7

2023-06-09

OAAI

Aldave, A. Asensio; Dommann, N.; Rossetti, G.; Karamichali, A.; Dionellis, V; Keogh, A.; Candinas, D.; Halazonetis, T.; Stroka, D.

DNA damage generated by transcription-replication conflicts explains the synthetic lethality of PARP inhibitors with homologous recombination deficiency

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Halazonetis, Thanos D.; Petropoulos, Michalis; Rossetti, Giacomo G.; Karamichali, Angeliki; Freudenmann, Alena; Iacovino, Luca; Dionellis, Vasilis; Sotiriou, Sotirios K.

An Oligomerized 53BP1 Tudor Domain Suffices for Recognition of DNA Double-Strand Breaks

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

119

OAAI

Zgheib, Omar; Pataky, Kristopher; Brugger, Juergen; Halazonetis, Thanos D.

Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage

JOURNAL OF PATHOLOGY

IF5.2

2022-11-09

OAAI

Petropoulos, Michalis; Tsaniras, Spyridon Champeris; Nikou, Sofia; Maxouri, Styliani; Dionellis, Vasilis S.; Kalogeropoulou, Argyro; Karamichali, Angeliki; Ioannidis, Konstantinos; Danalatos, Iosif-Rodolfos; Obst, Mandy; Naumann, Ronald; Delinasios, George J.; Gorgoulis, Vassilis G.; Roukos, Vassilis; Anastassiadis, Konstantinos; Halazonetis, Thanos D.; Bravou, Vasiliki; Lygerou, Zoi; Taraviras, Stavros

Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells

MOLECULAR CELL

IF16.6

2022-09-01

OAAI

Groelly, Florian J.; Dagg, Rebecca A.; Petropoulos, Michalis; Rossetti, Giacomo G.; Prasad, Birbal; Panagopoulos, Andreas; Paulsen, Teressa; Karamichali, Angeliki; Jones, Samuel E.; Ochs, Fena; Dionellis, Vasilis S.; Lombardi, Emilia Puig; Miossec, Matthieu J.; Lockstone, Helen; Legube, Gaelle; Blackford, Andrew N.; Altmeyer, Matthias; Halazonetis, Thanos D.; Tarsounas, Madalena

RAD51 protects human cells from transcription-replication conflicts RAD51保护人类细胞免受转录复制冲突

MOLECULAR CELL

IF16.6

2022-09-01

OAAI

Bhowmick, Rahul; Lerdrup, Mads; Gadi, Sampath Amitash; Rossetti, Giacomo G.; Singh, Manika I.; Liu, Ying; Halazonetis, Thanos D.; Hickson, Ian D.

Beating cancer one carbon at a time

NATURE CANCER

IF28.5

2022-02-28

PREAI

Dionellis, Vasilis S.; Halazonetis, Thanos D.

Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits

SCIENTIFIC REPORTS

IF3.9

2022-02-15

OAAI

Rossetti, Giacomo G.; Ossorio, Marianna A.; Rempel, Stephan; Kratzel, Annika; Dionellis, Vasilis S.; Barriot, Samia; Tropia, Laurence; Gorgulla, Christoph; Arthanari, Haribabu; Thiel, Volker; Mohr, Peter; Gamboni, Remo; Halazonetis, Thanos D.

Delayed DNA break repair for genome stability

NATURE CELL BIOLOGY

IF19.1

2021-10-06

PREAI

Petropoulos, Michalis; Halazonetis, Thanos D.

A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells

NATURE COMMUNICATIONS

IF15.7

2021-08-13

OAAI

Dagg, Rebecca A.; Zonderland, Gijs; Lombardi, Emilia Puig; Rossetti, Giacomo G.; Groelly, Florian J.; Barroso, Sonia; Tacconi, Eliana M. C.; Wright, Benjamin; Lockstone, Helen; Aguilera, Andres; Halazonetis, Thanos D.; Tarsounas, Madalena

Draining the FEN1s for cancer therapy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-08-18

OAAI

Rossetti, Giacomo G.; Sotiriou, Sotirios K.; Halazonetis, Thanos D.

High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

CELL RESEARCH

IF25.9

2020-06-19

OAAI

Macheret, Morgane; Bhowmick, Rahul; Sobkowiak, Katarzyna; Padayachy, Laura; Mailler, Jonathan; Hickson, Ian D.; Halazonetis, Thanos D.