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B

Berthold Göttgens

wellcome mrc cambridge stem cell institute
H指数:89
被引数:3.4万

个人简介

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荣誉奖项

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A step-wise, deterministic and fatal mouse model of myeloid neoplasm with spontaneous acquisition of patient-relevant RTK–RAS mutations

分步、确定性且致命的小鼠髓系肿瘤模型，可自发获得与患者相关的RTK–RAS突变

Oncogene
IF7.3
2026-09-040
OA
Marija A. Zarocsinceva; Moosa Qureshi; Nicola K. Wilson; George Giotopoulos; Blaise Musabe; Katherine H. M. Sturgess; M. S. Vijayabaskar; Sarah J. Kinston; Ryan Asby; David J. Adams; Brian J. P. Huntly; Fernando J. Calero-Nieto; Berthold Göttgens
A progeria syndrome links DNA hypermethylation to age-related pathology

早衰综合征将DNA高甲基化与年龄相关的病理学联系起来

Nature Genetics
IF29
2026-06-120
OAAI
Dan Sarni; Gráinne Neary; Paula L. Carroll; Chris S. Vink; Caroline V. Billard; Tomoya Isobe; Xiong Weng; Jordan R. Portman; Daniel L. McCartney; Patricia Heyn; Rob J. van ‘t Hof; Linda R. Morrison; Carol-Anne Martin; Colin Stok; Margaret E. Harley; Andrea Leitch; Maarten van den Ancker; Nic Robertson; Laura Kitto; Richard Clark; Michael Rennie; Anna Popravko; Jessica J. McClure; David A. Parry; Giuseppina Camiolo; Tom Leah; Hélène Jakobczyk; Roly Megaw; Lisa McKie; Grant F. Marshall; Nika Balkic; Jeanne Amiel; Tania Barragán Arévalo; Grace Bronken McCarthy; Catherine A. Buchanan; Alexandre Buffet; Alberto Cascón; Benjamin Cogne; Solene Conrad; Anna Maria Cueto-González; Maria Currás-Freixes; Gunnar Douzgos Houge; Chin-To Fong; Jaya K. George-Abraham; Kate Gibson; Lourdes Ibáñez; Nicola Longo; Charlotte Lussey-Lepoutre; Bradley S. Miller; Alejandro Moles-Fernandez; Nishitha R. Pillai; Tatiana Tvrdik; Marie Vincent; Emiy Yokoyama; Catherine M. Abbott; Francisco Jose Sanchez-Luque; Katrin Ottersbach; Cosimo De Bari; Anke J. Roelofs; Rebekah Tillotson; Kamil R. Kranc; Sara J. Brown; Riccardo E. Marioni; Mihaela Crisan; Berthold Göttgens; Neil C. Henderson; Robert K. Semple; Kevin B. Myant; Elaine Dzierzak; Martin A. M. Reijns; Duncan Sproul; Andrew P. Jackson
Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis

代谢物诱导的DNA损伤驱动随机干细胞丢失和克隆性造血

Cell Stem Cell
IF20.4
2026-03-230
OAAI
Ashley N. Kamimae-Lanning; Jill M. Brown; Matthias Günther; Franziska Esau; Holly Russell; Lise Larcher; Frédéric Langevin; Tomoya Isobe; Nicola K. Wilson; Felix A. Dingler; Rebecca L. Cordell; Meng Wang; Christopher L. Millington; Nina Claudino; Ewa Gogola; Matthew Nicholls; Verena Körber; Berthold Göttgens; Marella F.T.R. de Bruijn; Juan I. Garaycoechea
RNA terminal uridylyl transferases are druggable vulnerabilities in AML but are dispensable for normal hematopoiesis

RNA末端尿苷转移酶是急性髓系白血病中的可成药性易损靶点，但对正常造血是可有可无的

Science Advances
IF12.5
2026-01-010
OA
Christopher Mapperley; Elise Georges; Ali A. Azar; Yuka Kabayama; Hannah Lawson; Iwo Kuciński; Derek George; Joana Campos; Corey Fyfe; Jozef Durko; Wei Yee Chan; Lewis Allen; Babak Jazayeri; Edward Blacker; Louie N. van de Lagemaat; Aurélien Tripp; Theodoros I. Roumeliotis; Giulia Guiducci; Eleanor Herbert; Jasmin Paris; Jyoti S. Choudhary; George Poulogiannis; Robert M. Campbell; Marcos Morgan; Lovorka Stojic; Folkert Jacobus van Werven; Douglas Vernimmen; Berthold Göttgens; Dónal O’Carroll; Kamil R. Kranc
A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space

小鼠原肠形成和早期器官发生的时间-空间图谱，用于探索轴模式并将体外模型投射到体内空间

Cell Reports
IF6.9
2025-07-280
OA
Luke T.G. Harland; Tim Lohoff; Noushin Koulena; Nico Pierson; Constantin Pape; Farhan Ameen; Jonathan Griffiths; Bart Theeuwes; Nicola K. Wilson; Anna Kreshuk; Wolf Reik; Jennifer Nichols; Long Cai; John C. Marioni; Berthold Göttgens; Shila Ghazanfar
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes
GENOME RESEARCH
IF5.5
2024-07-010
OAAI
Xiang, Guanjue; He, Xi; Giardine, Belinda M.; Isaac, Kathryn J.; Taylor, Dylan J.; Mccoy, Rajiv C.; Jansen, Camden; Keller, Cheryl A.; Wixom, Alexander Q.; Cockburn, April; Miller, Amber; Qi, Qian; He, Yanghua; Li, Yichao; Lichtenberg, Jens; Heuston, Elisabeth F.; Anderson, Stacie M.; Luan, Jing; Vermunt, Marit W.; Yue, Feng; Sauria, Michael E. G.; Schatz, Michael C.; Taylor, James; Goettgens, Berthold; Hughes, Jim R.; Higgs, Douglas R.; Weiss, Mitchell J.; Cheng, Yong; Blobel, Gerd A.; Bodine, David M.; Zhang, Yu; Li, Qunhua; Mahony, Shaun; Hardison, Ross C.
Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells

自噬对抗衰老造血干细胞中炎症驱动的糖酵解障碍

CELL STEM CELL
IF20.4
2024-07-016
OAAI
V. Dellorusso, Paul; Proven, Melissa A.; Calero-Nieto, Fernando J.; Wang, Xiaonan; Mitchell, Carl A.; Hartmann, Felix; Amouzgar, Meelad; Favaro, Patricia; Devilbiss, Andrew; Swann, James W.; Ho, Theodore T.; Zhao, Zhiyu; Bendall, Sean C.; Morrison, Sean; Gottgens, Berthold; Passegue, Emmanuelle
A spatiotemporal atlas of mouse liver homeostasis and regeneration

小鼠肝脏稳态和再生的时空图谱

NATURE GENETICS
IF31.8
2024-04-166
PRE
Xu, Jiangshan; Guo, Pengcheng; Hao, Shijie; Shangguan, Shuncheng; Shi, Quan; Volpe, Giacomo; Huang, Keke; Zuo, Jing; An, Juan; Yuan, Yue; Cheng, Mengnan; Deng, Qiuting; Zhang, Xiao; Lai, Guangyao; Nan, Haitao; Wu, Baihua; Shentu, Xinyi; Wu, Liang; Wei, Xiaoyu; Jiang, Yujia; Huang, Xin; Pan, Fengyu; Song, Yumo; Li, Ronghai; Wang, Zhifeng; Liu, Chuanyu; Liu, Shiping; Li, Yuxiang; Yang, Tao; Xu, Zhicheng; Du, Wensi; Li, Ling; Ahmed, Tanveer; You, Kai; Dai, Zhen; Li, Li; Qin, Baoming; Li, Yinxiong; Lai, Liangxue; Qin, Dajiang; Chen, Junling; Fan, Rong; Li, Yongyin; Hou, Jinlin; Ott, Michael; Sharma, Amar Deep; Cantz, Tobias; Schambach, Axel; Kristiansen, Karsten; Hutchins, Andrew P.; Goettgens, Berthold; Maxwell, Patrick H.; Hui, Lijian; Xu, Xun; Liu, Longqi; Chen, Ao; Lai, Yiwei; Esteban, Miguel A.

研究方向

暂未获取到该数据
N
Nicola K. Wilson
H 指数:41论文数:150被引数:7,563
A
Anthony R. Green
H 指数:100论文数:596被引数:6.0万
F
Fernando J. Calero‐Nieto
H 指数:33论文数:96被引数:6,476
S
Sarah Kinston
H 指数:36论文数:101被引数:4,337
R
Rebecca Hannah
H 指数:27论文数:71被引数:4,107
V
Victoria Moignard
H 指数:18论文数:33被引数:2,509
J
John C. Marioni
H 指数:103论文数:401被引数:5.6万
X
Xiaonan Wang
H 指数:34论文数:257被引数:5,693
J
Jennifer Nichols
H 指数:76论文数:230被引数:4.0万
F
Fiona Hamey
H 指数:16论文数:45被引数:4,068