未登录 CDK6 inactivation counteracts CALR-mutant-induced MPN evolution and sensitizes MPN stem cells to interferon-α treatment CDK6失活对抗CALR突变诱导的MPN演化并使MPN干细胞对干扰素-α治疗敏感 Ringhofer, Brian; Polzer, Wolfram; Prchal-Murphy, Michaela; Doma, Eszter; Kollmann, Sebastian; Gamper, Elisabeth; Kendler, Jonatan; Maw, Belinda S.; Zebedin-Brandl, Eva; Li, Juan; Green, Anthony R.; Krauth, Maria-Theresa; Hadzijusufovic, Emir; Ivanov, Daniel; Valent, Peter; Hoermann, Gregor; Klampfl, Thorsten; Sexl, Veronika; Kollmann, Karoline 分享 收藏
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Comparative in vivo toxicology of ATR inhibitors ceralasertib, elimusertib, and berzosertib alone and in combination with ionizing radiation ATR抑制剂的体内比较毒理学研究：ceralasertib、elimusertib和berzosertib单药及与电离辐射联合使用的比较 Deppas, Joshua J.; Kiesel, Brian F.; Guo, Jianxia; Rigatti, Lora H.; Latoche, Joseph D.; Green, Anthony; Knizner, Paul; Clump, D. Andy; Pandya, Pinakin; Vendetti, Frank P.; Bakkenist, Christopher J. 分享 收藏
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment 致癌钙网蛋白通过刺激骨髓微环境中tgf β 表达和调节性T细胞扩增诱导免疫逃逸 Schmidt, Dominik; Endres, Cornelia; Hoefflin, Rouven; Andrieux, Geoffroy; Zwick, Melissa; Karantzelis, Nikolaos; Staehle, Hans F.; Vinnakota, Janaki Manoja; Duquesne, Sandra; Mozaffari Jovein, Miriam; Pfeifer, Dietmar; Becker, Heiko; Blazar, Bruce R.; Zaehringer, Alexander; Duyster, Justus; Brummer, Tilman; Boerries, Melanie; Baumeister, Julian; Shoumariyeh, Khalid; Li, Juan; Green, Anthony R.; Heidel, Florian H.; Tirosh, Itay; Pahl, Heike L.; Leimkuehler, Nils; Koehler, Natalie; de Toledo, Marcelo A. S.; Koschmieder, Steffen; Zeiser, Robert 分享 收藏
Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia Haage, Tobias Ronny; Charakopoulos, Emmanouil; Bhuria, Vikas; Baldauf, Conny K.; Korthals, Mark; Handschuh, Juliane; Mueller, Peter; Li, Juan; Harit, Kunjan; Nishanth, Gopala; Frey, Stephanie; Boettcher, Martin; Fischer, Klaus-Dieter; Dudeck, Jan; Dudeck, Anne; Lipka, Daniel B.; Schraven, Burkhart; Green, Anthony R.; Mueller, Andreas J.; Mougiakakos, Dimitrios; Fischer, Thomas 分享 收藏
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes Isobe, Tomoya; Kucinski, Iwo; Barile, Melania; Wang, Xiaonan; Hannah, Rebecca; Bastos, Hugo P.; Chabra, Shirom; Vijayabaskar, M. S.; Sturgess, Katherine H. M.; Williams, Matthew J.; Giotopoulos, George; Marando, Ludovica; Li, Juan; Rak, Justyna; Gozdecka, Malgorzata; Prins, Daniel; Shepherd, Mairi S.; Watcham, Sam; Green, Anthony R.; Kent, David G.; Vassiliou, George S.; Huntly, Brian J. P.; Wilson, Nicola K.; Gottgens, Berthold 分享 收藏
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms Grockowiak, Elodie; Korn, Claudia; Rak, Justyna; Lysenko, Veronika; Hallou, Adrien; Panvini, Francesca M.; Williams, Matthew; Fielding, Claire; Fang, Zijian; Khatib-Massalha, Eman; Garcia-Garcia, Andres; Li, Juan; Khorshed, Reema A.; Gonzalez-Anton, Sara; Baxter, E. Joanna; Kusumbe, Anjali; Wilkins, Bridget S.; Green, Anna; Simons, Benjamin D.; Harrison, Claire N.; Green, Anthony R.; Lo Celso, Cristina; Theocharides, Alexandre P. A.; Mendez-Ferrer, Simon 分享 收藏
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Transcriptional link between blood and bone:: the stem cell leukemia gene and its+19 stem cell enhancer are active in bone cells Pimanda, JE; Silberstein, L; Dominici, M; Dekel, B; Bowen, M; Oldham, S; Kallianpur, A; Brandt, SJ; Tannahill, D; Göttgens, B; Green, AR 分享 收藏
The scl +18/19 stem cell enhancer is not required for hematopoiesis:: Identification of a 5′ bifunctional hematopoietic-endothelial enhancer bound by Fli-1 and Elf-1 Göttgens, B; Broccardo, C; Sanchez, MJ; Deveaux, S; Murphy, G; Göthert, JR; Kotsopoulou, E; Kinston, S; Delaney, L; Piltz, S; Barton, LM; Knezevic, K; Erber, WN; Begley, CG; Frampton, J; Green, AR 分享 收藏
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cis-Regulatory Remodeling of the SCL Locus during Vertebrate Evolution Goettgens, Berthold; Ferreira, Rita; Sanchez, Maria-Jose; Ishibashi, Shoko; Li, Juan; Spensberger, Dominik; Lefevre, Pascal; Ottersbach, Katrin; Chapman, Michael; Kinston, Sarah; Knezevic, Kathy; Hoogenkamp, Maarten; Follows, George A.; Bonifer, Constanze; Amaya, Enrique; Green, Anthony R. 分享 收藏
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A primary nasopharyngeal three-dimensional air-liquid interface cell culture model of the pseudostratified epithelium reveals differential donor- and cell type-specific susceptibility to Epstein-Barr virus infection Ziegler, Phillip; Tian, Yarong; Bai, Yulong; Abrahamsson, Sanna; Baeckerholm, Alan; Reznik, Alex S.; Green, Anthony; Moore, John A.; Lee, Stella E.; Myerburg, Michael M.; Park, Hyun Jung; Tang, Ka-Wei; Shair, Kathy Ho Yen 分享 收藏
Broad Severe Acute Respiratory Syndrome Coronavirus 2 Cell Tropism and Immunopathology in Lung Tissues From Fatal Coronavirus Disease 2019 da Silva, Suzane Ramos; Ju, Enguo; Meng, Wen; Mondolfi, Alberto E. Paniz; Dacic, Sanja; Green, Anthony; Bryce, Clare; Grimes, Zachary; Fowkes, Mary; Sordillo, Emilia M.; Cordon-Cardo, Carlos; Guo, Haitao; Gao, Shou-Jiang 分享 收藏
Zinc-dependent multimerization of mutant calreticulin is required for MPL binding and MPN pathogenesis Rivera, Jeanne F.; Baral, April J.; Nadat, Fatima; Boyd, Grace; Smyth, Rachael; Patel, Hershna; Burman, Emma L.; Alameer, Ghadah; Boxall, Sally A.; Jackson, Brian R.; Baxter, E. Joanna; Laslo, Peter; Green, Anthony R.; Kent, David G.; Mullally, Ann; Chen, Edwin 分享 收藏
Hematopoietic stem cell heterogeneity is linked to the initiation and therapeutic response of myeloproliferative neoplasms (vol 28, pg 502, 2021) Tong, Jingyuan; Sun, Ting; Ma, Shihui; Zhao, Yanhong; Ju, Mankai; Gao, Yuchen; Zhu, Ping; Tan, Puwen; Fu, Rongfeng; Zhang, Anqi; Wang, Ding; Wang, Di; Xiao, Zhijian; Zhou, Jiaxi; Yang, Renchi; Loughran, Stephen J.; Li, Juan; Green, Anthony R.; Bresnick, Emery H.; Wang, Dong; Cheng, Tao; Zhang, Lei; Shi, Lihong 分享 收藏
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