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Cockayne syndrome mice reflect human kidney disease and are defective in de novo NAD biosynthesis Cockayne综合征小鼠反映了人类肾脏疾病,并且在新合成的NAD生物合成方面存在缺陷。 Pekhale, Komal; Tiwari, Vinod; Hussain, Mansoor; Bridges, Christy C.; Croteau, Deborah L.; Levi, Moshe; Rosenberg, Avi Z.; Santo, Briana; Yang, Xiaoping; Kulikowicz, Tomasz; Wang, Xiaoxin X.; Lee, Jong-Hyuk; Bohr, Vilhelm A. 分享 收藏
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Nicotinamide riboside modulates the reactive species interactome, bioenergetic status and proteomic landscape in a brain-region-specific manner 烟酰胺核苷以脑区域特异性方式调节反应性物种相互作用组,生物能量状态和蛋白质组学景观 Marmolejo-Garza, Alejandro; Chatre, Laurent; Croteau, Deborah L.; Herron-Bedoya, Alejandro; Luu, Minh Danh Anh; Bernay, Benoit; Pontin, Julien; Bohr, Vilhelm A.; Boddeke, Erik; Dolga, Amalia M. 分享 收藏
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Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions 尿石素A改善阿尔茨海默氏病的认知并恢复线粒体和溶酶体功能 Hou, Yujun; Chu, Xixia; Park, Jae-Hyeon; Zhu, Qing; Hussain, Mansoor; Li, Zhiquan; Madsen, Helena Borland; Yang, Beimeng; Wei, Yong; Wang, Yue; Fang, Evandro F.; Croteau, Deborah L.; Bohr, Vilhelm A. 分享 收藏
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The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops Wang, Yajun; Zhu, Wei; Jang, Yumi; Sommers, Joshua A.; Yi, Gong; Puligilla, Chandrakala; Croteau, Deborah L.; Yang, Yibin; Kai, Mihoko; Liu, Yie 分享 收藏
Long-term NAD plus supplementation prevents the progression of age-related hearing loss in mice Okur, Mustafa N.; Sahbaz, Burcin Duan; Kimura, Risako; Manor, Uri; Patel, Jaimin; Park, Jae-Hyeon; Andrade, Leo; Puligilla, Chandrakala; Croteau, Deborah L.; Bohr, Vilhelm A. 分享 收藏
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DNA Polymerase Beta Participates in Mitochondrial DNA Repair DNA聚合酶 β 参与线粒体DNA修复 Sykora, P.; Kanno, S.; Akbari, M.; Kulikowicz, T.; Baptiste, B. A.; Leandro, G. S.; Lu, H.; Tian, J.; May, A.; Becker, K. A.; Croteau, D. L.; Wilson, D. M., III; Sobol, R. W.; Yasui, A.; Bohr, V. A. 分享 收藏
Loss of smelling is an early marker of aging and is associated with inflammation and DNA damage in C57BL/6J mice Dan, Xiuli; Yang, Beimeng; McDevitt, Ross A.; Gray, Samuel; Chu, Xixia; Claybourne, Quia; Figueroa, David M.; Zhang, Yongqing; Croteau, Deborah L.; Bohr, Vilhelm A. 分享 收藏
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A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets Roberts, Jackson A.; Varma, Vijay R.; An, Yang; Varma, Sudhir; Candia, Julian; Fantoni, Giovanna; Tiwari, Vinod; Anerillas, Carlos; Williamson, Andrew; Saito, Atsushi; Loeffler, Tina; Schilcher, Irene; Moaddel, Ruin; Khadeer, Mohammed; Lovett, Jacqueline; Tanaka, Toshiko; Pletnikova, Olga; Troncoso, Juan C.; Bennett, David A.; Albert, Marilyn S.; Yu, Kaiwen; Niu, Mingming; Haroutunian, Vahram; Zhang, Bin; Peng, Junmin; Croteau, Deborah L.; Resnick, Susan M.; Gorospe, Myriam; Bohr, Vilhelm A.; Ferrucci, Luigi; Thambisetty, Madhav 分享 收藏