Sivaraj Sivaramakrishnan

university of minnesota system

H指数:33

被引数:3,627

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β-arrestin and myosin VI cooperatively control glucose-dependent insulinotropic peptide receptor (GIPR) internalization and signaling dynamics

β-arrestin和肌球蛋白VI协同调控葡萄糖依赖性促胰岛素肽受体(GIPR)的内吞及信号动力学

Journal of Biological Chemistry

IF3.9

2026-08-010

PRE

Kinetic Model of Partial Agonism Reveals Cellular Basis of Ligand Efficacy

部分激动剂动力学模型揭示了配体效力的细胞基础

Journal of Biological Chemistry

IF3.9

2026-05-210

OAAI

Selective positive allosteric modulation of β2AR using antibody fragments targeting the third intracellular loop

通过靶向第三胞内环的抗体片段选择性正向别构调节β2AR

Nature Communications

IF15.7

2026-05-060

OAAI

Allostery between Distant Structural Regions Dictates Selectivity in GPCR:G Protein Coupling

远距离结构区域间的别构作用决定了GPCR:G蛋白偶联的选择性

Biochemistry

IF3

2026-02-250

Temporally resolved and interpretable machine learning model of GPCR conformational transition

时空分辨且可解释的GPCR构象转换机器学习模型

Nature Communications

IF15.7

2025-12-060

OAAI

Myosin VI drives arrestin-independent internalization and signaling of GPCRs

NATURE COMMUNICATIONS

IF15.7

2024-12-060

OAAI

Tail length and E525K dilated cardiomyopathy mutant alter human β-cardiac myosin super-relaxed state

JOURNAL OF GENERAL PHYSIOLOGY

IF2.9

2024-05-064

OAAI

The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser359 Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-2018

OAAI

Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting-heads motif and super-relaxed state of myosin

人类 β-心肌肌球蛋白中的扩张型心肌病突变E525K稳定了相互作用的头部基序和肌球蛋白的超松弛状态

ELIFE

IF0

2022-11-248

Effect of Ligands and Transducers on the Neurotensin Receptor 1 Conformational Ensemble

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-06-0113

Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions

BIOPHYSICAL JOURNAL

IF3.1

2022-06-016

OAAI

Kinetic model of GPCR-G protein interactions reveals allokairic modulation of signaling

NATURE COMMUNICATIONS

IF15.7

2022-03-089

OAAI

Multimodal regulation of myosin VI ensemble transport by cargo adaptor protein GIPC

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-03-018

OAAI

β2-adrenoceptor ligand efficacy is tuned by a two-stage interaction with the Gαs C terminus

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-03-0816

KIF13A motors are regulated by Rab22A to function as weak dimers inside the cell

SCIENCE ADVANCES

IF12.5

2021-02-0515

OAAI

Kinase inhibitors allosterically disrupt a regulatory interaction to enhance PKCα membrane translocation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-012

OAAI

Dynamic multimerization of Dab2-Myosin VI complexes regulates cargo processivity while minimizing cortical actin reorganization

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-0111

OAAI

Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling

NATURE COMMUNICATIONS

IF15.7

2019-10-2322

OAAI

Conformational plasticity of the intracellular cavity of GPCR-G-protein complexes leads to G-protein promiscuity and selectivity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-05-2871

OAAI

Engaging myosin VI tunes motility, morphology and identity in endocytosis

TRAFFIC

IF2.5

2018-07-162

OAAI

Sivaraj Sivaramakrishnan

个人简介

教育背景

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