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N

Nagarajan Vaidehi

Beckman Research Institute of the City of Hope

50H指数
251论文数
8.0K被引数
收录论文 127
发表时间
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Conserved Residues in the Gα interface show subtype specificity in Gβγ couplingGα界面中的保守残基在Gβγ偶联中表现出亚型特异性
errJournal of Biological Chemistry
IF3.9
err2026-06-04
err0
errOAAI
errWenyuan Wei; H. Dalton Taylor; Ning Ma; Andrei S. Rodin; Sergio Branciamore; Henrik G. Dohlman; Nagarajan Vaidehi
err分享
err收藏
Selective positive allosteric modulation of β2AR using antibody fragments targeting the third intracellular loop通过靶向第三胞内环的抗体片段选择性正向别构调节β2AR
errNature Communications
IF15.7
err2026-05-06
err0
errOAAI
errEdgardo J. Sánchez Rivas; Fredrik Sadler; Mohammadamin Safdari; Nishaben M. Patel; Michael Ritt; Ning Ma; Sergio Branciamore; Nagarajan Vaidehi; Sivaraj Sivaramakrishnan
err分享
err收藏
DRUMBEAT temporally resolved interpretable machine learning model for characterizing state transitions in protein dynamics时序解析的机器学习模型用于表征蛋白质动力学中的状态转换
errCommunications Biology
IF5.1
err2026-04-15
err0
errOAAI
errBabgen Manookian; Elizaveta Mukhaleva; Grigoriy Gogoshin; Supriyo Bhattacharya; Nagarajan Vaidehi; Andrei S. Rodin; Sergio Branciamore
err分享
err收藏
Allosteric inhibition of RAN decreases miR-126 biogenesis in endothelial cells and controls acute myeloid leukemia growth别构抑制RAN降低内皮细胞中miR-126的生物发生并控制急性髓系白血病生长
errCommunications Biology
IF5.1
err2026-04-14
err0
errOAAI
errMelissa Valerio; Wenyuan Wei; Hyunjun Kang; Ning Ma; Supriyo Bhattacharya; Genevieve Baker; Weidong Hu; Lianjun Zhang; Dinh Hoa Hoang; Jia Feng; Hongyu Zhang; Bin Zhang; J. Jefferson P. Perry; Nagarajan Vaidehi; Le Xuan Truong Nguyen; Guido Marcucci
err分享
err收藏
Allostery between Distant Structural Regions Dictates Selectivity in GPCR:G Protein Coupling远距离结构区域间的别构作用决定了GPCR:G蛋白偶联的选择性
errBiochemistry
IF3
err2026-02-25
err0
errOAAI
errElizaveta Mukhaleva; Edgardo J. Sánchez Rivas; Sergio Branciamore; Andrei S. Rodin; Sivaraj Sivaramakrishnan; Nagarajan Vaidehi
err分享
err收藏
Dynamic feedback control of oncogenic tyrosine kinase signaling in acute leukemia急性白血病中致癌酪氨酸激酶信号通路的动态反馈控制
errScience Signaling
IF6.6
err2026-02-10
err0
PREAI
errJaewoong Lee; Ruifeng Sun; Kohei Kume; Mark E. Robinson; Zhangliang Cheng; Kadriye Nehir Cosgun; Ning Ma; Christian Hurtz; Huimin Geng; Selina M. Luger; Mark R. Litzow; Elisabeth Paietta; Jianjun Chen; Nagarajan Vaidehi; Markus Müschen
err分享
err收藏
Temporally resolved and interpretable machine learning model of GPCR conformational transition时空分辨且可解释的GPCR构象转换机器学习模型
errNature Communications
IF15.7
err2025-12-06
err0
errOAAI
errBabgen Manookian; Elizaveta Mukhaleva; Grigoriy Gogoshin; Supriyo Bhattacharya; Sivaraj Sivaramakrishnan; Nagarajan Vaidehi; Andrei S. Rodin; Sergio Branciamore
err分享
err收藏
Allosteric communication mechanism in the glucagon receptor胰高血糖素受体的别构通讯机制
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-06-01
err0
errOAAI
errvan der Velden, Wijnand J. C.; Mukhaleva, Elizaveta; Vaidehi, Nagarajan
err分享
err收藏
BaNDyT: Bayesian Network Modeling of Molecular Dynamics Trajectories
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-01-23
err0
PREAI
errMukhaleva, Elizaveta; Manookian, Babgen; Chen, Hanyu; Sivaraj, Indira R.; Ma, Ning; Wei, Wenyuan; Urbaniak, Konstancja; Gogoshin, Grigoriy; Bhattacharya, Supriyo; Vaidehi, Nagarajan; Rodin, Andrei S.; Branciamore, Sergio
err分享
err收藏
Insights from protein frustration analysis of BRD4-cereblon degrader ternary complexes show separation of strong from weak degraders
errRSC MEDICINAL CHEMISTRY
IF3.6
err2025-01-01
err0
PREAI
errYang, Tianyi; Mukhaleva, Elizaveta; Wei, Wenyuan; Weiss, Dahlia; Ma, Ning; Shanmugasundaram, Veerabahu; Vaidehi, Nagarajan
err分享
err收藏
Myosin VI drives arrestin-independent internalization and signaling of GPCRs
errNATURE COMMUNICATIONS
IF15.7
err2024-12-06
err0
errOAAI
errPatel, Nishaben M.; Ripoll, Lea; Peach, Chloe J.; Ma, Ning; Blythe, Emily E.; Vaidehi, Nagarajan; Bunnett, Nigel W.; von Zastrow, Mark; Sivaramakrishnan, Sivaraj
err分享
err收藏
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state神经发育障碍突变将g蛋白锁定在短暂的预激活状态
errNATURE COMMUNICATIONS
IF15.7
err2024-08-05
err0
errOAAI
errKnight, Kevin M.; Krumm, Brian E.; Kapolka, Nicholas J.; Ludlam, W. Grant; Cui, Meng; Mani, Sepehr; Prytkova, Iya; Obarow, Elizabeth G.; Lefevre, Tyler J.; Wei, Wenyuan; Ma, Ning; Huang, Xi-Ping; Fay, Jonathan F.; Vaidehi, Nagarajan; Smrcka, Alan V.; Slesinger, Paul A.; Logothetis, Diomedes E.; Martemyanov, Kirill A.; Roth, Bryan L.; Dohlman, Henrik G.
err分享
err收藏
Bayesian network models identify cooperative GPCR:G protein interactions that contribute to G protein coupling
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-06-01
err2
errOAAI
errMukhaleva, Elizaveta; Ma, Ning; Velden, Wijnand J. C. van der; Gogoshin, Grigoriy; Branciamore, Sergio; Bhattacharya, Supriyo; Rodin, Andrei S.; Vaidehi, Nagarajan
err分享
err收藏
Dynamic recruitment of inhibitory complexes by CD25 controls B-cell development and selection
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errSun, Ruifeng; Lee, Jaewoong; Robinson, Mark; Kume, Kohei; Ma, Ning; Cosgun, Kadriye Nehir; Chan, Lai; Antoshkina, Irina; Khanduja, Dhruv; Leveille, Etienne; Katz, Samuel; Vaidehi, Nagarajan; Mueschen, Markus
err分享
err收藏
Stabilization of interdomain interactions in G protein α subunits as a determinant of Gαi subtype signaling specificity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-05-01
err1
errOAAI
errLefevre, Tyler J.; Wei, Wenyuan; Mukhaleva, Elizaveta; Venkata, Sai Pranathi Meda; Chandan, Naincy R.; Abraham, Saji; Li, Yong; Dessauer, Carmen W.; Vaidehi, Nagarajan; V. Smrcka, Alan
err分享
err收藏
Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3
errMOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
err2024-03-01
err5
errOAAI
errHall, Jeremy; Zhang, Zhuoran; Bhattacharya, Supriyo; Wang, Dongfang; Alcantara, Marice; Liang, Yong; Swiderski, Piotr; Forman, Stephen; Kwak, Larry; Vaidehi, Nagarajan; Kortylewski, Marcin
err分享
err收藏
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
errSCIENCE ADVANCES
IF12.5
err2024-02-23
err2
errOAAI
errChan, Anthony K. N.; Han, Li; Delaney, Christopher D.; Wang, Xueer; Mukhaleva, Elizaveta; Li, Mingli; Yang, Lu; Pokharel, Sheela Pangeni; Mattson, Nicole; Garcia, Michelle; Wang, Bintao; Xu, Xiaobao; Zhang, Leisi; Singh, Priyanka; Elsayed, Zeinab; Chen, Renee; Kuang, Benjamin; Wang, Jinhui; Yuan, Yate-Ching; Chen, Bryan; Chan, Lai N.; Rosen, Steven T.; Horne, David; Muschen, Markus; Chen, Jianjun; Vaidehi, Nagarajan; Armstrong, Scott A.; Su, Rui; Chen, Chun-Wei
err分享
err收藏
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-02-05
err5
errOAAI
errMattson, Nicole M.; Chan, Anthony K. N.; Miyashita, Kazuya; Mukhaleva, Elizaveta; Chang, Wen-Han; Yang, Lu; Ma, Ning; Wang, Yingyu; Pokharel, Sheela Pangeni; Li, Mingli; Liu, Qiao; Xu, Xiaobao; Chen, Renee; Singh, Priyanka; Zhang, Leisi; Elsayed, Zeinab; Chen, Bryan; Keen, Denise; Pirrotte, Patrick; Rosen, Steven. T.; Chen, Jianjun; Labarge, Mark A.; Shively, John E.; Vaidehi, Nagarajan; Rockne, Russell C.; Feng, Mingye; Chen, Chun-Wei
err分享
err收藏
Molecular annotation of G protein variants in a neurological disorder (vol 42, 113462, 2023)
errCELL REPORTS
IF6.9
err2023-12-01
err0
errOAAI
errKnight, Kevin M.; Obarow, Elizabeth G.; Wei, Wenyuan; Mani, Sepehr; Esteller, Maria I.; Cui, Meng; Ma, Ning; Martin, Sarah A.; Brinson, Emily; Hewitt, Natalie; Soden, Gaby M.; Logothetis, Diomedes E.; Vaidehi, Nagarajan; Dohlman, Henrik G.
err分享
err收藏
Molecular annotation of G protein variants in a neurological disorder
errCELL REPORTS
IF6.9
err2023-12-01
err5
errOAAI
errKnight, Kevin M.; Obarow, Elizabeth G.; Wei, Wenyuan; Mani, Sepehr; Esteller, Maria I.; Cui, Meng; Ma, Ning; Martin, Sarah A.; Brinson, Emily; Hewitt, Natalie; Soden, Gaby M.; Logothetis, Diomedes E.; Vaidehi, Nagarajan; Dohlman, Henrik G.
err分享
err收藏

研究方向

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合作学者
合作期刊
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William A. Goddard
H 指数: 184 · 论文数: 2.4K
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B
Brian K. Kobilka
H 指数: 140 · 论文数: 520
B
Bryan L. Roth
H 指数: 139 · 论文数: 971
S
Stephen J. Forman
H 指数: 127 · 论文数: 1.8K
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