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D

Donald Küfe

dana-farber cancer institute

123H指数
1.2K论文数
5.0W被引数
收录论文 210
发表时间
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M1C is a druggable target for NSCLC KRAS G12C mutant tumors resistant to KRAS inhibitorsM1C是耐药KRAS抑制剂的非小细胞肺癌KRAS G12C突变肿瘤的可成药靶点
errOncogene
IF7.3
err2026-08-05
err0
errOAAI
errShinkichi Takamori; Naoki Haratake; Atrayee Bhattacharya; Hiroki Ozawa; Keisuke Shigeta; Mai Onishi; Kentaro Nonaka; Takefumi Komiya; Hiroki Komatsuda; Tomoyoshi Takenaka; Tomoharu Yoshizumi; Chendi Li; Jiehui Deng; Aaron N. Hata; Kwok K. Wong; Mark D. Long; Donald Kufe
err分享
err收藏
M1C Mediates LINE-1 Transcription in PARP Inhibitor-Treated Prostate Cancer CellsM1C 介导 PARP 抑制剂处理的 prostate cancer cells 中 LINE-1 的转录
errCancer Letters
IF10.1
err2026-02-12
err0
PREAI
errKeisuke Shigeta; Shinkichi Takamori; Hiroki Ozawa; Naoki Haratake; Mai Onishi; Tatsuaki Daimon; Tomohiro Kitano; Atrayee Bhattacharya; Atsushi Fushimi; Mototsugu Oya; Mark D. Long; Donald Kufe
err分享
err收藏
MUCIN 1 confers inflammatory memory of tyrosine kinase inhibitor resistance in non-small cell lung cancer黏蛋白1赋予非小细胞肺癌酪氨酸激酶抑制剂耐药的炎症记忆
errSignal Transduction and Targeted Therapy
IF52.7
err2025-11-28
err0
errOAAI
errShinkichi Takamori; Naoki Haratake; Atrayee Bhattacharya; Chie Kikutake; Hiroki Ozawa; Keisuke Shigeta; Ayako Nakashoji; Hideko Isozaki; Mototsugu Shimokawa; Mikita Suyama; Asato Hashinokuchi; Kazuki Takada; Gouji Toyokawa; Yuichi Yamada; Tomoyoshi Takenaka; Kenichi Taguchi; Masafumi Yamaguchi; Tomoharu Yoshizumi; Aaron N. Hata; Donald Kufe
err分享
err收藏
Activation of APOBEC3 cytidine deaminases and endogenous retroviruses is integrated by MUC1-C in NSCLC cellsMUC1-C在NSCLC细胞中将APOBEC3胞嘧啶脱氨酶和内源性逆转录病毒的激活进行整合。
errCell Death Discovery
IF7
err2025-08-08
err0
errOAAI
errNaoki Haratake; Shinkichi Takamori; Hideko Isozaki; Keisuke Shigeta; Chie Kikutake; Hiroki Ozawa; Atrayee Bhattacharya; Ayako Nakashoji; Mikita Suyama; Tomoyoshi Takenaka; Tomoharu Yoshizumi; Atsushi Osoegawa; Aaron N. Hata; Donald Kufe
err分享
err收藏
MUC1-C auto-regulatory complex with EBNA1 is responsible for latent Epstein-Barr virus-associated gastric cancer progressionMUC1-C与EBNA1的自调控复合物负责潜伏性EB病毒相关胃癌的进展
errOncogene
IF7.3
err2025-08-05
err0
errOAAI
errHiroki Ozawa; Yin Wang; Henry G. Withers; Naoki Haratake; Ayako Nakashoji; Atrayee Bhattacharya; Atsushi Fushimi; Chie Kikutake; Kazuhiro Yamanoi; Shaowen White; Keyi Wang; Tatsuaki Daimon; Keisuke Shigeta; Kazumasa Fukuda; Hirofumi Kawakubo; Yuko Kitagawa; Mark D. Long; Benjamin E. Gewurz; Donald Kufe
err分享
err收藏
MUC1-C dependency in drug resistant HR+/HER2- breast cancer identifies a new target for antibody-drug conjugate treatmentMUC1-C依赖性在药物耐药的HR+/HER2-乳腺癌中确定了一种新型抗体药物偶联物治疗靶点
errNPJ BREAST CANCER
IF7.6
err2025-04-26
err0
errOAAI
errNakashoji, Ayako; Bhattacharya, Atrayee; Ozawa, Hiroki; Haratake, Naoki; Shigeta, Keisuke; Fushimi, Atsushi; Yamashita, Nami; Matsui, Akira; Kure, Shoko; Kameyama, Tomoe; Takeuchi, Makoto; Fukuda, Kazumasa; Yokoe, Takamichi; Nagayama, Aiko; Hayahsida, Tetsu; Kitagawa, Yuko; Liu, Renyan; Giordano, Antonio; Jeselsohn, Rinath; Shapiro, Geoffrey I.; Kufe, Donald
err分享
err收藏
MUC1-C Dependence for the Progression of Pancreatic Neuroendocrine Tumors Identifies a Druggable Target for the Treatment of This Rare Cancer
errBIOMEDICINES
IF3.9
err2024-07-08
err0
errOAAI
errOzawa, Hiroki; Haratake, Naoki; Nakashoji, Ayako; Daimon, Tatsuaki; Bhattacharya, Atrayee; Wang, Keyi; Shigeta, Keisuke; Fushimi, Atsushi; Fukuda, Kazumasa; Masugi, Yohei; Yamaguchi, Ryo; Kitago, Minoru; Kawakubo, Hirofumi; Kitagawa, Yuko; Kufe, Donald
err分享
err收藏
MUC1-C regulates NEAT1 lncRNA expression and paraspeckle formation in cancer progressionMUC1-C在癌症进展中调节NEAT1 lncRNA表达和副斑点形成
errONCOGENE
IF7.3
err2024-05-27
err2
errOAAI
errBhattacharya, Atrayee; Wang, Keyi; Penailillo, Johany; Chan, Chi Ngai; Fushimi, Atsushi; Yamashita, Nami; Daimon, Tatsuaki; Haratake, Naoki; Ozawa, Hiroki; Nakashoji, Ayako; Shigeta, Keisuke; Morimoto, Yoshihiro; Miyo, Masaaki; Kufe, Donald W.
err分享
err收藏
XIST and MUC1-C form an auto-regulatory pathway in driving cancer progression
errCELL DEATH & DISEASE
IF9.6
err2024-05-13
err5
errOAAI
errWang, Keyi; Bhattacharya, Atrayee; Haratake, Naoki; Daimon, Tatsuaki; Nakashoji, Ayako; Ozawa, Hiroki; Peng, Bo; Li, Wei; Kufe, Donald
err分享
err收藏
MUC1-C INTEGRATES CHRONIC ACTIVATION OF INTERFERON PATHWAYS WITH CHROMATIN REMODELING IN TREATMENT RESISTANCE OF TRIPLE-NEGATIVE BREAST CANCER
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errYamashita, Nami; Morimoto, Yoshihiro; Fushimi, Atsushi; Ahmad, Rehan; Bhattacharya, Atrayee; Inoue, Yuka; Withers, Henry; Shapiro, Geoffrey; Yoshizumi, Tomoharu; Ueno, Takayuki; Ohno, Shinji; Long, Mark; Kufe, Donald
err分享
err收藏
MUC1 is necessary for the inflammatory memory response to osimertinib resistance in NSCLC cells
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHaratake, Naoki; Bhattacharya, Atrayee; Nakashoji, Ayako; Ozawa, Hiroki; Shimokawa, Mototsugu; Kufe, Donald
err分享
err收藏
MUC1-C is a target of salinomycin in inducing ferroptosis of cancer stem cells
errCELL DEATH DISCOVERY
IF7
err2024-01-05
err3
errOAAI
errDaimon, Tatsuaki; Bhattacharya, Atrayee; Wang, Keyi; Haratake, Naoki; Nakashoji, Ayako; Ozawa, Hiroki; Morimoto, Yoshihiro; Yamashita, Nami; Kosaka, Takeo; Oya, Mototsugu; Kufe, Donald W.
err分享
err收藏
MUC1-C is a common driver of acquired osimertinb resistance in NSCLC
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errHaratake, Naoki; Ozawa, Hiroki; Morimoto, Yoshihiro; Yamashita, Nami; Daimon, Tatsuaki; Bhattacharya, Atrayee; Wang, Keyi; Nakashoji, Ayako; Isozaki, Hideko; Hata, Aaron; Kufe, Donald
err分享
err收藏
MUC1-C intersects chronic inflammation with epigenetic reprogramming by regulating the set1a compass complex in cancer progressionMUC1-C通过调节set1a compass复合物在癌症进展中将慢性炎症与表观遗传重编程交叉
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-10-11
err12
errOAAI
errBhattacharya, Atrayee; Fushimi, Atsushi; Wang, Keyi; Yamashita, Nami; Morimoto, Yoshihiro; Ishikawa, Satoshi; Daimon, Tatsuaki; Liu, Tao; Liu, Song; Long, Mark D.; Kufe, Donald
err分享
err收藏
The Cancer Moonshot Immuno-Oncology Translational Network at 5: accelerating cancer immunotherapies
errJNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
IF7.2
err2023-08-12
err0
errOAAI
errAnnapragada, Ananth; Sikora, Andrew G.; Marathe, Himangi; Liu, Song; Demetriou, Michael; Fong, Lawrence; Gao, Jinming; Kufe, Donald; Morris, Zachary S.; Vilar, Eduardo; Sharon, Elad; Hutson, Alan; Odunsi, Kunle
err分享
err收藏
4-1bb selection augments DC/AML fusion vaccine-educated T cells for adoptive cell therapy
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errRallis, Kathrine S.; Liegel, Jessica; Cheloni, Giulia; Stroopinsky, Dina; Bindal, Poorva; Dufort, Kenel; Torres, Daniela; Saldarriaga, Isabella; Herzlinger, Samuel; Morin, Abigael; Kesselman, Raphael; Rosenbaum, Jeremy; Chedid, Georges; Adamia, Sophia; Kufe, Donald; Rosenblatt, Jacalyn; Avigan, David
err分享
err收藏
MUC1-C is necessary for SHP2 activation and BRAF inhibitor resistance in BRAF(V600E) mutant colorectal cancerMUC1-C是BRAF(V600E) 突变型结直肠癌中SHP2激活和BRAF抑制剂耐药所必需的
errCANCER LETTERS
IF10.1
err2023-04-01
err10
errOAAI
errMorimoto, Yoshihiro; Yamashita, Nami; Hirose, Haruka; Fushimi, Atsushi; Haratake, Naoki; Daimon, Tatsuaki; Bhattacharya, Atrayee; Ahmad, Rehan; Suzuki, Yozo; Takahashi, Hidekazu; Kufe, Donald W.
err分享
err收藏
Targeting of the c-Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress-induced Apoptosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err135
errOAAI
errIto, Y; Pandey, P; Mishra, N; Kumar, S; Narula, N; Kharbanda, S; Saxena, S; Kufe, D
err分享
err收藏
Inactivation of DNA-dependent protein kinase by protein kinase Cδ:: Implications for apoptosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err227
errOAAI
errBharti, A; Kraeft, SK; Gounder, M; Pandey, P; Jin, SF; Yuan, ZM; Lees-Miller, SP; Weichselbaum, R; Weaver, D; Chen, LB; Kufe, D; Kharbanda, S
err分享
err收藏
Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err85
errOAAI
errKharbanda, S; Pandey, P; Yamauchi, T; Kumar, S; Kaneki, M; Kumar, V; Bharti, A; Yuan, ZM; Ghanem, L; Rana, A; Weichselbaum, R; Johnson, G; Kufe, D
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
K
Kenneth C. Anderson
H 指数: 199 · 论文数: 3.1K
N
Nahum Sonenberg
H 指数: 178 · 论文数: 957
G
Gordon J. Freeman
H 指数: 174 · 论文数: 1.1K
A
Alessandro Sette
H 指数: 174 · 论文数: 1.4K
R
Roger J. Davis
H 指数: 166 · 论文数: 852
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