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The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states 儿童癌症分层医学儿科计划: 无细胞DNA和连续肿瘤测序确定亚型特异性进化和表观遗传状态 George, Sally L.; Lynn, Claire; Stankunaite, Reda; Hughes, Debbie; Chalker, Jane; Ahmed, Saira Waqar; Oostveen, Minou; Proszek, Paula; Yuan, Lina; Shaikh, Ridwan; Jamal, Sabri; Tall, Jennifer; Shipley, Janet; Tweddle, Deborah; Marshall, Lynley; Jones, Chris; Gatz, Susanne; Vedi, Aditi; Angelini, Paola; Anderson, John; Cresswell, George; Graham, Trevor A.; Al-Lazikani, Bissan; Kearns, Pamela; Hutchinson, J. Ciaran; Hargrave, Darren; Jacques, Thomas; Hubank, Michael; Sottoriva, Andrea; Chesler, Louis 分享 收藏
Reappraisal of prognostic factors used in the European Pediatric Soft Tissue Sarcoma Study Group RMS 2005 study for localized rhabdomyosarcoma to optimize risk stratification and generate a prognostic nomogram De Salvo, Gian Luca; Del Bianco, Paola; Minard-Colin, Veronique; Chisholm, Julia; Jenney, Meriel; Guillen, Gabriela; Devalck, Christine; Van Rijn, Rick; Shipley, Janet; Orbach, Daniel; Kelsey, Anna; Rogers, Timothy; Guerin, Florent; Scarzello, Giovanni; Ferrari, Andrea; Cesen Mazic, Maja; Merks, Johannes H. M.; Bisogno, Gianni 分享 收藏
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting Pomella, Silvia; Cassandri, Matteo; D'Archivio, Lucrezia; Porrazzo, Antonella; Cossetti, Cristina; Phelps, Doris; Perrone, Clara; Pezzella, Michele; Cardinale, Antonella; Wachtel, Marco; Aloisi, Sara; Milewski, David; Colletti, Marta; Sreenivas, Prethish; Walters, Zoe S.; Barillari, Giovanni; Di Giannatale, Angela; Milano, Giuseppe Maria; De Stefanis, Cristiano; Alaggio, Rita; Rodriguez-Rodriguez, Sonia; Carlesso, Nadia; Vakoc, Christopher R.; Velardi, Enrico; Schafer, Beat W.; Guccione, Ernesto; Gatz, Susanne A.; Wasti, Ajla; Yohe, Marielle; Ignatius, Myron; Quintarelli, Concetta; Shipley, Janet; Miele, Lucio; Khan, Javed; Houghton, Peter J.; Marampon, Francesco; Gryder, Berkley E.; De Angelis, Biagio; Locatelli, Franco; Rota, Rossella 分享 收藏
Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells O'Brien, Eleanor; Tse, Carmen; Tracy, Ian; Reddin, Ian; Selfe, Joanna; Gibson, Jane; Tapper, William; Pengelly, Reuben J.; Gao, Jinhui; Aladowicz, Ewa; Petts, Gemma; Thway, Khin; Popov, Sergey; Kelsey, Anna; Underwood, Timothy J.; Shipley, Janet; Walters, Zoe S. 分享 收藏
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Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue sarcoma Study Group, Children's Oncology Group and Cooperative Weichteilsarkom-Studiengruppe Hettmer, Simone; Linardic, Corinne M.; Kelsey, Anna; Rudzinski, Erin R.; Vokuhl, Christian; Selfe, Joanna; Ruhen, Olivia; Shern, Jack F.; Khan, Javed; Kovach, Alexander R.; Lupo, Philip J.; Gatz, Susanne A.; Schaefer, Beat W.; Volchenboum, Samuel; Minard-Colin, Veronique; Koscielniak, Ewa; Hawkins, Douglas S.; Bisogno, Gianni; Sparber-Sauer, Monika; Venkatramani, Rajkumar; Merks, Johannes H. M.; Shipley, Janet 分享 收藏
FGF7-FGFR2 autocrine signaling increases growth and chemoresistance of fusion-positive rhabdomyosarcomas Milton, Christopher I.; Selfe, Joanna; Aladowicz, Ewa; Man, Stella Y. K.; Bernauer, Carolina; Missiaglia, Edoardo; Walters, Zoe S.; Gatz, Susanne A.; Kelsey, Anna; Generali, Melanie; Box, Gary; Valenti, Melanie; de Haven-Brandon, Alexis; Galiwango, David; Hayes, Angela; Clarke, Matthew; Izquierdo, Elisa; Gonzalez De Castro, David; Raynaud, Florence I.; Kirkin, Vladimir; Shipley, Janet M. 分享 收藏
Non-parameningeal head and neck rhabdomyosarcoma in children, adolescents, and young adults: Experience of the European paediatric Soft tissue sarcoma Study Group (EpSSG)-RMS2005 study Glosli, Heidi; Bisogno, Gianni; Kelsey, Anna; Chisholm, Julia C.; Gaze, Mark; Kolb, Frederic; McHugh, Kieran; Shipley, Janet; Gallego, Soledad; Merks, Johannes H. M.; Smeele, Ludi E.; Mandeville, Henry; Ferrari, Andrea; Minard-Colin, Veronique; Corradini, Nadege; Jenney, Meriel; Zanetti, Ilaria; De Salvo, Gian L.; Orbach, Daniel 分享 收藏
Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response Zhang, Ping; Kitchen-Smith, Isaac; Xiong, Lingyun; Stracquadanio, Giovanni; Brown, Katherine; Richter, Philipp H.; Wallace, Marsha D.; Bond, Elisabeth; Sahgal, Natasha; Moore, Samantha; Nornes, Svanhild; De Val, Sarah; Surakhy, Mirvat; Sims, David; Wang, Xuting; Bell, Douglas A.; Zeron-Medina, Jorge; Jiang, Yanyan; Ryan, Anderson J.; Selfe, Joanna L.; Shipley, Janet; Kar, Siddhartha; Pharoah, Paul D.; Loveday, Chey; Jansen, Rick; Grochola, Lukasz F.; Palles, Claire; Protheroe, Andrew; Millar, Val; Ebner, Daniel, V; Pagadala, Meghana; Blagden, Sarah P.; Maughan, Timothy S.; Domingo, Enric; Tomlinson, Ian; Turnbull, Clare; Carter, Hannah; Bond, Gareth L. 分享 收藏
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Genomic landscape of platinum resistant and sensitive testicular cancers 铂类耐药和敏感睾丸癌的基因组景观 Loveday, Chey; Litchfield, Kevin; Proszek, Paula Z.; Cornish, Alex J.; Santo, Flavia; Levy, Max; Macintyre, Geoff; Holryod, Amy; Broderick, Peter; Dudakia, Darshna; Benton, Barbara; Al Bakir, Maise; Hiley, Crispin; Grist, Emily; Swanton, Charles; Huddart, Robert; Powles, Tom; Chowdhury, Simon; Shipley, Janet; O'Connor, Simon; Brenton, James D.; Reid, Alison; de Castro, David Gonzalez; Houlston, Richard S.; Turnbull, Clare 分享 收藏
Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death Ommer, Johannes; Selfe, Joanna L.; Wachtel, Marco; O'Brien, Eleanor M.; Laubscher, Dominik; Roemmele, Michaela; Kasper, Stephanie; Delattre, Olivier; Surdez, Didier; Petts, Gemma; Kelsey, Anna; Shipley, Janet; Schafer, Beat W. 分享 收藏
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A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations George, Sally L.; Izquierdo, Elisa; Campbell, James; Koutroumanidou, Eleni; Proszek, Paula; Jamal, Sabri; Hughes, Deborah; Yuan, Lina; Marshall, Lynley V.; Carceller, Fernando; Chisholm, Julia C.; Vaidya, Sucheta; Mandeville, Henry; Angelini, Paola; Wasti, Ajla; Bexelius, Tomas; Thway, Khin; Gatz, Susanne A.; Clarke, Matthew; Al-Lazikani, Bissan; Barone, Giuseppe; Anderson, John; Tweddle, Deborah A.; Gonzalez, David; Walker, Brian A.; Barton, Jack; Depani, Sarita; Eze, Jessica; Ahmed, Saira W.; Moreno, Lucas; Pearson, Andrew; Shipley, Janet; Jones, Chris; Hargrave, Darren; Jacques, Thomas S.; Hubank, Michael; Chesler, Louis 分享 收藏
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VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle Figeac, Nicolas; Mohamed, Abdalla D.; Sun, Congshan; Schoenfelder, Martin; Matallanas, David; Garcia-Munoz, Amaya; Missiaglia, Edoardo; Collie-Duguid, Elaina; De Mello, Vanessa; Pobbati, Ajaybabu V.; Pruller, Johanna; Jaka, Oihane; Harridge, Stephen D. R.; Hong, Wanjin; Shipley, Janet; Vargesson, Neil; Zammit, Peter S.; Wackerhage, Henning 分享 收藏
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