Lachlan Coin - Publications, H-index & Citations

Lachlan Coin

University of Melbourne

66H指数

356论文数

7.1W被引数

收录论文 129

发表时间

Interrogating the Escherichia coli Epitranscriptome Via CRISPR Interference and Nanopore Native RNA Sequencing 通过CRISPR干扰和纳米孔原位RNA测序探究大肠杆菌表观转录组

MicrobiologyOpen

IF4.6

2026-09-24

OAAI

Miranda E. Pitt; Jianshu Zhang; An N. T. Nguyen; Michael B. Hall; Leila Jebeli; Leo A. Featherstone; Garry S. A. Myers; Nichollas E. Scott; Lachlan J. M. Coin

Customizable host and viral transcript enrichment using CRISPR–Cas9 long-read sequencing for characterization of low-to-moderate abundance isoforms 利用CRISPR–Cas9长读长测序技术实现宿主和病毒转录本的可定制富集，以表征低至中等丰度的异构体

NAR Genomics and Bioinformatics

IF2.8

2026-09-15

OAAI

An N T Nguyen; Jianshu Zhang; Shuxin Zhang; Miranda E Pitt; Devika Ganesamoorthy; Svenja Fritzlar; Jessie J -Y Chang; Sarah L Londrigan; Lachlan J M Coin

Predicting trajectories of illness using RNA velocity of whole blood 利用全血RNA速度预测疾病轨迹

Nature Communications

IF15.7

2026-05-06

OAAI

Claire Dunican; Clare Wilson; Dominic Habgood-Coote; Suzanna Paterson; Mahdad Noursadeghi; Raymond Moseki; Cari Stek; Robert J. Wilkinson; Philipp K. A. Agyeman; Coco R. Beudeker; Giske Biesbroek; Ulrich von Both; Karen Brengel-Pesce; Enitan D. Carrol; Lachlan J. M. Coin; Giselle D’Souza; Tisham De; Marieke Emonts; Katy Fidler; Colin G. Fink; Michiel van der Flier; Ioanna Georgaki; Laura Kolberg; Mojca Kolnik; Taco Kuijpers; Federico Martinón-Torres; Marine Mommert-Tripon; Samuel Nichols; Stephane Paulus; Marko Pokorn; Andrew J. Pollard; Irene Rivero-Calle; Aleksandra Rudzate; Luregn J. Schlapbach; Nina A. Schweintzger; Ching-Fen Shen; Shrijana Shrestha; Chantal D. Tan; Maria Tsolia; Effua Usuf; Fabian van der Velden; Clementien L. Vermont; Marie Voice; Shunmay Yeung; Dace Zavadska; Werner Zenz; Victoria J. Wright; Michael Levin; Jethro Herberg; Rachel P. J. Lai; Graeme Meintjes; Christopher Chiu; Mauricio Barahona; Myrsini Kaforou; Aubrey J. Cunnington

Genome graphs reveal the importance of structural variation in Mycobacterium tuberculosis evolution and drug resistance 基因组图谱揭示了结构变异在 *Mycobacterium tuberculosis* 进化和药物耐药性中的重要性。

Nature Communications

IF15.7

2025-11-28

OAAI

Aleix Canalda-Baltrons; Matthew Silcocks; Michael B. Hall; Derrick Theys; Xuling Chang 常戌灵; Linda T. Viberg; Norelle L. Sherry; Lachlan Coin; Sarah J. Dunstan

Genome size estimation from long read overlaps 基于长读序列重叠的基因组大小估计

BIOINFORMATICS

IF5.4

2025-11-01

OAAI

Hall, Michael B.; Zhou, Chenxi; Coin, Lachlan J. M.

Invasive Streptococcus dysgalactiae subspecies equisimilis compared with Streptococcus pyogenes in Australia, 2011–23, and the emergence of a multi-continent stG62647 lineage: a retrospective clinical and genomic epidemiology study 侵袭性 Streptococcus dysgalactiae subspecies equisimilis 与 Streptococcus pyogenes 在澳大利亚（2011–23年）的比较，以及一个多大陆 stG62647 谱系的兴起：一项回顾性临床和基因组流行病学研究

The Lancet Microbe

IF0

2025-10-07

OAAI

Ouli Xie; Leo Featherstone; An N T Nguyen; Andrew J Hayes; Miranda E Pitt; Stephanie Spring; Alice Liu; Gerry Tonkin-Hill; Ravindra Dotel; Neela Joshi Rai; Alexander Rofe; Sebastian Duchêne; Deborah C Holt; Louise M Judd; Lachlan J M Coin; Vicki L Krause; Matthew V N O’Sullivan; Robert W Baird; Katherine Bond; Benjamin P Howden; Tony M Korman; Bart J Currie; Mark R Davies; Steven Y C Tong

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long-Read RNA Sequencing 利用长读长RNA测序表征欧洲家养雪貂呼吸道组织对干扰素和感染的转录组学应答

IMMUNOLOGY

IF5

2025-10-01

OAAI

Farrukee, Rubaiyea; Chang, Jessie J. -Y.; Zhang, Jianshu; Barnes, James B.; Zhang, Shu Xin; Tan, Sher Maine; Reading, Patrick C.; Coin, Lachlan J. M.

Finding the optimal regimen for Mycobacteroides abscessus treatment (FORMaT) in people with Mycobacteroides abscessus pulmonary disease: a multicentre, randomised, multi-arm, adaptive platform trial 在分枝杆菌脓肿亚种肺部疾病患者中寻找最佳治疗方案（FORMaT）：一项多中心、随机、多臂、自适应平台试验

BMJ OPEN

IF2.3

2025-09-21

OAAI

Jong, Tiffany; Baird, Timothy; Barr, Helen Louise; Bell, Scott; Bigirumurame, Theophile; Brady, Kara; Burke, Andrew; Byrnes, Joshua; Caudri, Daan; Clark, Julia E.; Coin, Lachlan J. M.; Goh, Felicia; Grimwood, Keith; Hicks, Daniel; Jayawardana, Kaushala; Joshi, Sri; Lee, Katherine; Qvist, Tavs; Reid, David; Rice, Megan; Roberts, Jason A.; Rogers, Geraint; Shackleton, Claire; Sly, Peter D.; Smyth, Alan R.; Stevens, Luke; Stockwell, Rebecca; Tarique, Abdullah; Taylor, Steven; Thomson, Rachel; Tiddens, Harm A. W. M.; Wang, Xiao Fang; Wason, James; Wainwright, Claire

Using synthetic RNA to benchmark poly(A) length inference from direct RNA sequencing 利用合成RNA评估直接RNA测序中poly(A)长度的推断

GigaScience

IF3.9

2025-09-03

OAAI

Jessie J -Y Chang; Xuan Yang; Haotian Teng; Jianshu Zhang; Benjamin Reames; Shuxin Zhang; Vincent Corbin; Lachlan J M Coin

Impact of human lifestyle on the pathogenic potential of urban wastewater 人类生活方式对城市废水致病潜力的影晌

Environmental Research

IF7.7

2025-08-12

OAAI

Jiangping Wu; Yan Chen; Jiawei Zhao; Jake William O'Brien; Lachlan Coin; Faisal I. Hai; Martina Sanderson-Smith; Guangming Jiang

Characterisation of in vitro resistance selection against second-/last-line antibiotics in methicillin-resistant Staphylococcus aureus ATCC 43300 strain 甲氧西林耐药金黄色葡萄球菌ATCC 43300菌株对二线/末线抗生素的体外耐药选择特征

JAC-ANTIMICROBIAL RESISTANCE

IF3.3

2025-06-01

OAAI

Prasetyoputri, Anggia; Pitt, Miranda E.; Cao, Minh Duc; Ramu, Soumya; Kavanagh, Angela; Elliott, Alysha G.; Ganesamoorthy, Devika; Monk, Ian R.; Stinear, Timothy P.; Cooper, Matthew A.; Coin, Lachlan J. M.; Blaskovich, Mark A. T.

Utilizing Nanopore direct RNA sequencing of blood from patients with sepsis for discovery of co- and post-transcriptional disease biomarkers 利用纳米孔直接RNA测序分析脓毒症患者血液，以发现共转录和转录后疾病生物标志物

BMC INFECTIOUS DISEASES

IF3

2025-05-13

OAAI

He, Jingni; Ganesamoorthy, Devika; Chang, Jessie J. Y.; Zhang, Jianshu; Trevor, Sharon L.; Gibbons, Kristen S.; McPherson, Stephen J.; Kling, Jessica C.; Schlapbach, Luregn J.; Blumenthal, Antje; Coin, Lachlan J. M.

Plasma metabolomic signatures for copy number variants and COVID-19 risk loci in Northern Finland populations 血浆代谢组学特征：北芬兰人群中的拷贝数变异和COVID-19风险位点

SCIENTIFIC REPORTS

IF3.9

2025-04-16

OAAI

De, Tisham; Coin, Lachlan; Herberg, Jethro; Johnson, Michael R.; Jarvelin, Marjo-Riitta

DIAGNOSING PEDIATRIC SEPSIS WITH SEPTICYTE RAPID HOST GENE EXPRESSION 利用Septicyte快速宿主基因表达诊断儿科脓毒症

CRITICAL CARE MEDICINE

IF6

2025-01-30

PREAI

Zimmerman, Jerry; Schlapbach, Luregn; Gibbons, Kristen; Cermelli, Silvia; Coin, Lachlan; Davis, Roy; Irwin, Adam; George, Shane; Navalkar, Krupa; Raman, Sainath; Yager, Thomas; Brandon, Richard

Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

ELIFE

IF0

2024-10-10

OAAI

Hall, Michael B.; Wick, Ryan R.; Judd, Louise M.; Nguyen, An N.; Steinig, Eike J.; Xie, Ouli; Davies, Mark; Seemann, Torsten; Stinear, Timothy P.; Coin, Lachlan

Wastewater Microbiome Analysis for Population Alcohol Abuse

WATER

IF3

2024-07-30

OAAI

Wu, Jiangping; Chen, Yan; Zhao, Jiawei; Prosun, Tanjila Alam; O'Brien, Jake William; Coin, Lachlan; Hai, Faisal I.; Sanderson-Smith, Martina; Jiang, Guangming

Sustained transmission over two decades of a previously unrecognised MPT64 negative Mycobacterium tuberculosis strain in Queensland, Australia: a whole genome sequencing study

LANCET REGIONAL HEALTH-WESTERN PACIFIC

IF8.1

2024-06-01

OAAI

Bainomugisa, Arnold; Pandey, Sushil; O'Connor, Bridget; Syrmis, Melanie; Whiley, David; Sintchenko, Vitali; Coin, Lachlan J. M.; Marais, Ben J.; Coulter, Christopher

Host gene expression signatures to identify infection type and organ dysfunction in children evaluated for sepsis: a multicentre cohort study

LANCET CHILD & ADOLESCENT HEALTH

IF15.5

2024-05-01

OAAI

Schlapbach, Luregn J.; Ganesamoorthy, Devika; Wilson, Clare; Raman, Sainath; George, Shane; Snelling, Peter J.; Phillips, Natalie; Irwin, Adam; Sharp, Natalie; Le Marsney, Renate; Chavan, Arjun; Hempenstall, Allison; Bialasiewicz, Seweryn; Macdonald, Anna; Grimwood, Keith; Kling, Jessica C.; Mcpherson, Stephen J.; Blumenthal, Antje; Kaforou, Myrsini; Levin, Michael; Herberg, Jethro A.; Gibbons, Kristen S.; Coin, Lachlan J. M.

Pangenome databases improve host removal and mycobacteria classification from clinical metagenomic data Pangenome数据库从临床宏基因组数据中改善宿主去除和分枝杆菌分类

GIGASCIENCE

IF3.9

2024-04-04

OAAI

Hall, Michael B.; Coin, Lachlan J. M.

Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis (Mar, 10.1007/s00134-024-07353-3, 2024)

INTENSIVE CARE MEDICINE

IF21.2

2024-04-02

OAAI

Chai, Ming G.; Tu, Quyen; Cotta, Menino O.; Bauer, Michelle J.; Balch, Ross; Okafor, Charles; Comans, Tracy; Kruger, Peter; Meyer, Jason; Shekar, Kiran; Brady, Kara; Fourie, Cheryl; Sharp, Natalie; Vlad, Luminita; Whiley, David; Ungerer, Jacobus P. J.; Mcwhinney, Brett C.; Farkas, Andras; Paterson, David L.; Clark, Julia E.; Hajkowicz, Krispin; Raman, Sainath; Bialasiewicz, Seweryn; Lipman, Jeffrey; Forde, Brian M.; Harris, Patrick N. A.; Schlapbach, Luregn J.; Coin, Lachlan; Roberts, Jason A.; Irwin, Adam D.

研究方向