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High 4E-BP1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing sarcoma 高4E-BP1表达与染色体8获得及CDK4/6敏感性在尤因肉瘤中相关联 Funk, Cornelius M.; Ehlers, Anna C.; Orth, Martin F.; Aljakouch, Karim; Li, Jing; Holting, Tilman L. B.; Will, Rainer; Geyer, Florian H.; Ceranski, A. Katharina; Willis, Franziska; Vinca, Endrit; Ohmura, Shunya; Imle, Roland; Siebenlist, Jana; Yershova, Angelina; Knott, Maximilian M. L.; Zahnow, Felina; Sastre, Ana; Alonso, Javier; Sahm, Felix; Peterziel, Heike; Loboda, Anna; Schneider, Martin; Banito, Ana; Leprivier, Gabriel; Hartmann, Wolfgang; Dirksen, Uta; Witt, Olaf; Oehme, Ina; Pfister, Stefan M.; Romero-Perez, Laura; Krijgsveld, Jeroen; Cidre-Aranaz, Florencia; Grunewald, Thomas G. P.; Musa, Julian 分享 收藏
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Establishment of patient-derived 3D in vitro models of sarcomas: literature review and guidelines on behalf of the FORTRESS working group 建立来源于患者的肉瘤3D体外模型：文献综述和FORTRESS工作组指南 De Cock, Lore; Palubeckaite, Ieva; Bersani, Francesca; Faehling, Tobias; Pasquali, Sandro; Umbaugh, Sam; Meister, Michael Torsten; Danks, Molly R.; Manasterski, Piotr; Miallot, Richard; Krumbholz, Manuela; Roohani, Siyer; Heymann, Dominique; Cidre-Aranaz, Florencia; Wozniak, Agnieszka; Schoffski, Patrick; Bovee, Judith V. M. G.; Merlini, Alessandra; Venneker, Sanne 分享 收藏
Multi-omics profiling reveals key factors involved in Ewing sarcoma metastasis 多组学分析揭示尤文肉瘤转移的关键因素 Chicon-Bosch, Mariona; Sanchez-Serra, Sara; Rosas-Lapena, Marta; Costa-Fraga, Nicolas; Besalu-Velazquez, Judit; Illa-Bernadi, Janet; Mateo-Lozano, Silvia; Cidre-Aranaz, Florencia; Gruenewald, Thomas G. P.; Diaz-Lagares, Angel; Lopez-Alemany, Roser; Tirado, Oscar M. 分享 收藏
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A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling 富含棕榈酸酯的转移生态位通过p65乙酰化实现转移生长，从而导致促转移nf-κb信号传导 Altea-Manzano, Patricia; Doglioni, Ginevra; Liu, Yawen; Cuadros, Alejandro M.; Nolan, Emma; Fernandez-Garcia, Juan; Wu, Qi; Planque, Melanie; Laue, Kathrin Julia; Cidre-Aranaz, Florencia; Liu, Xiao-Zheng; Marin-Bejar, Oskar; Van Elsen, Joke; Vermeire, Ines; Broekaert, Dorien; Demeyer, Sofie; Spotbeen, Xander; Idkowiak, Jakub; Montagne, Aurelie; Demicco, Margherita; Alkan, H. Furkan; Rabas, Nick; Riera-Domingo, Carla; Richard, Francois; Geukens, Tatjana; De Schepper, Maxim; Leduc, Sophia; Hatse, Sigrid; Lambrechts, Yentl; Kay, Emily Jane; Lilla, Sergio; Alekseenko, Alisa; Geldhof, Vincent; Boeckx, Bram; de la Calle Arregui, Celia; Floris, Giuseppe; Swinnen, Johannes V.; Marine, Jean-Christophe; Lambrechts, Diether; Pelechano, Vicent; Mazzone, Massimiliano; Zanivan, Sara; Cools, Jan; Wildiers, Hans; Baud, Veronique; Gruenewald, Thomas G. P.; Ben-David, Uri; Desmedt, Christine; Malanchi, Ilaria; Fendt, Sarah-Maria 分享 收藏
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation Orth, Martin F.; Surdez, Didier; Faehling, Tobias; Ehlers, Anna C.; Marchetto, Aruna; Grossetete, Sandrine; Volckmann, Richard; Zwijnenburg, Danny A.; Gerke, Julia S.; Zaidi, Sakina; Alonso, Javier; Sastre, Ana; Baulande, Sylvain; Sill, Martin; Cidre-Aranaz, Florencia; Ohmura, Shunya; Kirchner, Thomas; Hauck, Stefanie M.; Reischl, Eva; Gymrek, Melissa; Pfister, Stefan M.; Strauch, Konstantin; Koster, Jan; Delattre, Olivier; Grunewald, Thomas G. . P. 分享 收藏
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis (Sept, 10.1007/s13402-022-00713-5, 2022) Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Caterina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grunewald, Thomas G. P.; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia 分享 收藏
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Matzek, Dana; Popper, Bastian; Jacobi, Severin J.; Funk, Cornelius M.; Geyer, Florian H.; Li, Jing; Piseddu, Ignazio; Cadilha, Bruno L.; Ledderose, Stephan; Zwilling, Jennifer; Ohmura, Shunya; Anz, David; Kuenkele, Annette; Klauschen, Frederick; Gruenewald, Thomas G. P.; Knott, Maximilian M. L. 分享 收藏
ABCA6 affects the malignancy of Ewing sarcoma cells via cholesterol-guided inhibition of the IGF1R/AKT/MDM2 axis Pasello, Michela; Giudice, Anna Maria; Cristalli, Camilla; Manara, Maria Cristina; Mancarella, Caterina; Parra, Alessandro; Serra, Massimo; Magagnoli, Giovanna; Cidre-Aranaz, Florencia; Grunewald, Thomas G. P.; Bini, Carla; Lollini, Pier-Luigi; Longhi, Alessandra; Donati, Davide Maria; Scotlandi, Katia 分享 收藏
Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1 Deng, Qu; Natesan, Ramakrishnan; Cidre-Aranaz, Florencia; Arif, Shehbeel; Liu, Ying; Rasool, Reyaz ur; Wang, Pei; Mitchell-Velasquez, Erick; Das, Chandan Kanta; Vinca, Endrit; Cramer, Zvi; Grohar, Patrick J.; Chou, Margaret; Kumar-Sinha, Chandan; Weber, Kristy; Eisinger-Mathason, T. S. Karin; Grillet, Nicolas; Gruenewald, Thomas; Asangani, Irfan A. 分享 收藏
Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma Berthold, Ruth; Isfort, Ilka; Erkut, Cihan; Heinst, Lorena; Gruenewald, Inga; Wardelmann, Eva; Kindler, Thomas; Aman, Pierre; Gruenewald, Thomas G. P.; Cidre-Aranaz, Florencia; Trautmann, Marcel; Froehling, Stefan; Scholl, Claudia; Hartmann, Wolfgang 分享 收藏
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma Cidre-Aranaz, Florencia; Li, Jing; Hoelting, Tilman L. B.; Orth, Martin F.; Imle, Roland; Kutschmann, Stefanie; Ammirati, Giuli; Ceranski, Katharina; Carreno-Gonzalez, Martha Julia; Kasan, Merve; Marchetto, Aruna; Funk, Cornelius M.; Bestvater, Felix; Bersini, Simone; Arrigoni, Chiara; Moretti, Matteo; Thiel, Uwe; Baumhoer, Daniel; Sahm, Felix; Pfister, Stefan M.; Hartmann, Wolfgang; Dirksen, Uta; Romero-Perez, Laura; Banito, Ana; Ohmura, Shunya; Musa, Julian; Kirchner, Thomas; Knott, Maximilian M. L.; Grunewald, Thomas G. P. 分享 收藏
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer Li, Jing; Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Imle, Roland; Dallmayer, Marlene; Musa, Julian; Knott, Maximilian M. L.; Holting, Tilman L. B.; Stein, Stefanie; Funk, Cornelius M.; Sastre, Ana; Alonso, Javier; Bestvater, Felix; Kasan, Merve; Romero-Perez, Laura; Hartmann, Wolfgang; Ranft, Andreas; Banito, Ana; Dirksen, Uta; Kirchner, Thomas; Cidre-Aranaz, Florencia; Gruenewald, Thomas G. P. 分享 收藏
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma RRM2作为尤文肉瘤预后生物标志物和治疗靶点的翻译证据 Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Li, Jing; Jabar, Susanne; Ranft, Andreas; Vinca, Endrit; Ceranski, Katharina; Carreno-Gonzalez, Martha J.; Romero-Perez, Laura; Wehweck, Fabienne S.; Musa, Julian; Bestvater, Felix; Knott, Maximilian M. L.; Hoelting, Tilman L. B.; Hartmann, Wolfgang; Dirksen, Uta; Kirchner, Thomas; Cidre-Aranaz, Florencia; Grunewald, Thomas G. P. 分享 收藏
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma (vol 11, 2423, 2020) Marchetto, Aruna; Ohmura, Shunya; Orth, Martin F.; Knott, Maximilian M. L.; Colombo, Maria V.; Arrigoni, Chiara; Bardinet, Victor; Saucier, David; Wehweck, Fabienne S.; Li, Jing; Stein, Stefanie; Gerke, Julia S.; Baldauf, Michaela C.; Musa, Julian; Dallmayer, Marlene; Romero-Perez, Laura; Holting, Tilman L. B.; Amatruda, James F.; Cossarizza, Andrea; Henssen, Anton G.; Kirchner, Thomas; Moretti, Matteo; Cidre-Aranaz, Florencia; Sannino, Giuseppina; Grunewald, Thomas G. P. 分享 收藏
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